CHPT1 and TLCD4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CHPT1	TLCD4
Description		choline phosphotransferase 1	TLC domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Endomembrane System Membrane Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Membrane
	Molecular Function	Diacylglycerol Cholinephosphotransferase Activity Protein Binding Transferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Diacylglycerol Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of Cell Growth Lipid Metabolic Process Phosphatidylcholine Biosynthetic Process CDP-choline Pathway Platelet Activating Factor Biosynthetic Process Phospholipid Biosynthetic Process	Lipid Homeostasis
Pathways		Synthesis of PC
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Orofacial clefts ( 33137956) Vitamin C levels ( 33203707)
Interacting Genes		4 interacting genes: DRD2 HTR2B LTB4R2 TLCD4	72 interacting genes: ADGRB3 ADGRE2 ARV1 ATP13A1 BNIP3 CACNG1 CCDC167 CDIPT CFTR CHPT1 CLCN7 CLEC7A CMTM5 COMT CTXN3 CXCL16 CYP4F2 CYP4F22 DHRSX EBP EMC6 EMP1 ERG28 FA2H FDFT1 FXYD6 FXYD6-FXYD2 GJB2 GOSR2 GYPA HMOX1 IGFBP5 KRT1 LNPEP MS4A13 MYG1 NAT8 NDUFA3 NINJ1 NKG7 ORMDL1 PMP22 PRAF2 PRRT2 REEP6 SCAMP5 SCD SEC22A SEC22B SERP1 SFXN1 SFXN3 SLC41A1 SLC67A1 SMAGP STATH STX12 SYNDIG1 SYNJ2BP TIMM23 TMEM115 TMEM120B TMEM19 TMEM229B TMEM237 TMEM60 TMIE TVP23B UBE2J1 VEZT YIPF1 YIPF4
Entrez ID		56994	148534
HPRD ID		13052	08110
Ensembl ID		ENSG00000111666	ENSG00000152078
Uniprot IDs		Q8WUD6	Q96MV1
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Alpha-subunit Binding Release Of Sequestered Calcium Ion Into Cytosol Smooth Muscle Contraction G Protein-coupled Receptor Activity Negative Regulation Of Sequestering Of Calcium Ion Regulation Of Behavior Calcium Ion Transmembrane Import Into Cytosol Positive Regulation Of Cell Division Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Calcium Ion Transmembrane Transport Chemical Homeostasis Negative Regulation Of Circadian Sleep/wake Cycle, Sleep G Protein-coupled Receptor Complex Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Division Cell Migration Negative Regulation Of Dopamine Secretion Calcium Ion Homeostasis Muscle Contraction Intracellular Calcium Ion Homeostasis Negative Regulation Of Dopamine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cell Motility Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process G Protein-coupled Serotonin Receptor Complex Intestine Smooth Muscle Contraction Ameboidal-type Cell Migration Leukotriene Signaling Pathway Leukotriene B4 Receptor Activity Leukotriene Receptor Activity Dopamine Binding Dopamine Neurotransmitter Receptor Activity Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Negative Regulation Of Dephosphorylation Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Branching Morphogenesis Of A Nerve Calcium Ion Transport Positive Regulation Of Neurotransmitter Uptake Muscle System Process Regulation Of Locomotion Involved In Locomotory Behavior	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Sterol Biosynthetic Process Lipid Biosynthetic Process Cholesterol Biosynthetic Process SNAP Receptor Activity Steroid Biosynthetic Process Membrane Fusion Serine Import Into Mitochondrion Lipid Metabolic Process Sterol Metabolic Process Cholesterol Transport Establishment Of Protein Localization Sterol Transport Membrane Organization Organic Cation Transport Import Into The Mitochondrion Protein Transport L-serine Transmembrane Transporter Activity L-serine Transport Protein Binding Bleb Assembly Serine Transport Vesicle Fusion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?