CHPT1

Description		choline phosphotransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Endomembrane System Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Diacylglycerol Cholinephosphotransferase Activity Protein Binding Transferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Diacylglycerol Binding Metal Ion Binding
	Biological Process	Regulation Of Cell Growth Lipid Metabolic Process Phosphatidylcholine Biosynthetic Process CDP-choline Pathway Platelet Activating Factor Biosynthetic Process Phospholipid Biosynthetic Process
Pathways		Synthesis of PC
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Orofacial clefts ( 33137956) Vitamin C levels ( 33203707)
Interacting Genes		4 interacting genes: DRD2 HTR2B LTB4R2 TLCD4
Entrez ID		56994
HPRD ID		13052
Ensembl ID		ENSG00000111666
Uniprot IDs		Q8WUD6
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Alpha-subunit Binding Release Of Sequestered Calcium Ion Into Cytosol Smooth Muscle Contraction G Protein-coupled Receptor Activity Negative Regulation Of Sequestering Of Calcium Ion Regulation Of Behavior Calcium Ion Transmembrane Import Into Cytosol Positive Regulation Of Cell Division Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Calcium Ion Transmembrane Transport Chemical Homeostasis Negative Regulation Of Circadian Sleep/wake Cycle, Sleep G Protein-coupled Receptor Complex Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Division Cell Migration Negative Regulation Of Dopamine Secretion Calcium Ion Homeostasis Muscle Contraction Intracellular Calcium Ion Homeostasis Negative Regulation Of Dopamine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cell Motility Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process G Protein-coupled Serotonin Receptor Complex Intestine Smooth Muscle Contraction Ameboidal-type Cell Migration Leukotriene Signaling Pathway Leukotriene B4 Receptor Activity Leukotriene Receptor Activity Dopamine Binding Dopamine Neurotransmitter Receptor Activity Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Negative Regulation Of Dephosphorylation Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Branching Morphogenesis Of A Nerve Calcium Ion Transport Positive Regulation Of Neurotransmitter Uptake Muscle System Process Regulation Of Locomotion Involved In Locomotory Behavior
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