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GOLGA2 and PSMA1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
GOLGA2
PSMA1
Description
golgin A2
proteasome 20S subunit alpha 1
Image
GO Annotations
Cellular Component
Golgi Cis Cisterna
Golgi Membrane
Spindle Pole
Cytoplasm
Golgi Apparatus
Cis-Golgi Network
Cytoskeleton
Microtubule
Membrane
COPII-coated ER To Golgi Transport Vesicle
Golgi Cisterna Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Mitotic Spindle
Proteasome Complex
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Proteasome Core Complex
Proteasome Core Complex, Alpha-subunit Complex
Extracellular Exosome
Molecular Function
Protein Binding
Microtubule Binding
Protein Kinase Binding
Syntaxin Binding
Identical Protein Binding
Cadherin Binding
Importin-alpha Family Protein Binding
Lipopolysaccharide Binding
Protein Binding
Biological Process
Protein Glycosylation
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Microtubule Nucleation
Golgi Organization
Centrosome Cycle
Asymmetric Cell Division
Negative Regulation Of Autophagy
Protein Transport
Negative Regulation Of Protein Binding
Spindle Assembly
Protein Homotetramerization
Cell Division
Positive Regulation Of Protein Glycosylation
Golgi Ribbon Formation
Golgi Disassembly
Meiotic Spindle Assembly
Mitotic Spindle Assembly
Immune System Process
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Pathways
Golgi Cisternae Pericentriolar Stack Reorganization
Golgi Cisternae Pericentriolar Stack Reorganization
COPII-mediated vesicle transport
COPI-mediated anterograde transport
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Activation of NF-kappaB in B cells
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
ER-Phagosome pathway
ER-Phagosome pathway
Cross-presentation of soluble exogenous antigens (endosomes)
Autodegradation of Cdh1 by Cdh1:APC/C
SCF-beta-TrCP mediated degradation of Emi1
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Vpu mediated degradation of CD4
Vif-mediated degradation of APOBEC3G
SCF(Skp2)-mediated degradation of p27/p21
Degradation of beta-catenin by the destruction complex
Downstream TCR signaling
Regulation of activated PAK-2p34 by proteasome mediated degradation
Separation of Sister Chromatids
FCERI mediated NF-kB activation
Autodegradation of the E3 ubiquitin ligase COP1
Regulation of ornithine decarboxylase (ODC)
ABC-family proteins mediated transport
AUF1 (hnRNP D0) binds and destabilizes mRNA
Asymmetric localization of PCP proteins
Degradation of AXIN
Degradation of DVL
Hedgehog ligand biogenesis
Hh mutants are degraded by ERAD
Dectin-1 mediated noncanonical NF-kB signaling
CLEC7A (Dectin-1) signaling
Degradation of GLI1 by the proteasome
Degradation of GLI2 by the proteasome
GLI3 is processed to GLI3R by the proteasome
Hedgehog 'on' state
Regulation of RAS by GAPs
TNFR2 non-canonical NF-kB pathway
NIK-->noncanonical NF-kB signaling
Defective CFTR causes cystic fibrosis
MAPK6/MAPK4 signaling
UCH proteinases
Ub-specific processing proteases
Assembly of the pre-replicative complex
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
G2/M Checkpoints
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
Ubiquitin-dependent degradation of Cyclin D
The role of GTSE1 in G2/M progression after G2 checkpoint
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Regulation of RUNX2 expression and activity
Regulation of RUNX2 expression and activity
Regulation of RUNX3 expression and activity
Regulation of PTEN stability and activity
Neddylation
Regulation of expression of SLITs and ROBOs
Interleukin-1 signaling
Negative regulation of NOTCH4 signaling
KEAP1-NFE2L2 pathway
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
Degradation of CDH1
Somitogenesis
Antigen processing: Ubiquitination & Proteasome degradation
Proteasome assembly
Proteasome assembly
Antigen processing: Ub, ATP-independent proteasomal degradation
GSK3B-mediated proteasomal degradation of PD-L1(CD274)
SPOP-mediated proteasomal degradation of PD-L1(CD274)
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Degradation of CRY and PER proteins
Degradation of CRY and PER proteins
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Drugs
(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE
Diseases
GWAS
Adult body size (
32376654
)
Body mass index (
26426971
)
Alzheimer's disease (cognitive decline) (
23535033
)
Bipolar disorder (
31043756
)
Diastolic blood pressure (
27841878
)
Femur bone mineral density x serum urate levels interaction (
34046847
)
HDL cholesterol levels (
32203549
)
High chromosomal aberration frequency (total) (
31586183
)
Hip circumference adjusted for BMI (
34021172
)
Hip index (
34021172
)
Skin and soft tissue infections (
33662382
)
Systolic blood pressure (
27841878
)
Triglyceride levels (
32154731
32203549
)
Vitamin D levels (
25208829
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
465 interacting genes:
ABHD17A
ABLIM1
ADAP1
AFF4
AIRIM
ALKBH2
ALKBH3
AMOTL2
ANKHD1
ANKRD11
ANKRD36
ANKRD36BP1
ANKS1A
APC
AQP1
ARFIP2
ARHGAP45
ARHGEF6
ARID5A
ARL16
ARL4A
ARNT2
ARPC3
ATOSA
ATOSB
ATP5PO
ATP6V1C2
ATP6V1D
ATP6V1G1
ATXN7
AXIN1
BAHD1
BARD1
BAZ2B
BCAS2
BCL6
BCL6B
BMS1P1
BYSL
C12orf50
C19orf44
C1orf35
CAB39
CAPN7
CATSPERT
CBX8
CBY2
CCAR1
CCDC120
CCDC13
CCDC146
CCDC150
CCDC17
CCDC185
CCDC187
CCDC198
CCDC70
CCDC87
CCDC92
CCHCR1
CCNC
CCNH
CDC20B
CDC37
CDC5L
CDC7
CDC73
CDCA7L
CDK1
CDK18
CDKL3
CDKN1A
CENPP
CEP55
CEP57L1
CEP95
CHCHD2
CHCHD3
CIC
CINP
CKB
CLIP3
COG6
CORO1A
COX5B
CRACR2A
CRMP1
CSPP1
CSTF2T
CUL5
CWF19L2
CYB5R2
DAXX
DCTN4
DCX
DDX6
DEUP1
DGCR6
DLG4
DLGAP3
DLGAP5
DLX6-AS1
DMTN
DNM2
DRC4
DTX2
DVL2
EAF2
EFCAB6
EFHC1
EGR2
EIF3G
EIF4A2
ENKD1
ENPP7
EP300
ERCC3
ESCO2
EXOC8
EXOSC5
FAM110A
FAM124B
FAM161A
FAM161B
FAM184A
FAM193B
FAM50B
FAM90A1
FANCG
FBF1
FBXL18
FBXO28
FIP1L1
FNDC11
FOXC2
FOXP1
FXR1
FXR2
GADD45GIP1
GAS2L2
GATA1
GATA2
GATAD2B
GCC1
GEM
GFAP
GGA2
GGN
GLYCTK
GMCL1
GNG5
GNL3L
GORASP1
GORASP2
GPANK1
GPKOW
GPS2
GRAP2
GRB14
GSE1
GTPBP10
GZMA
GZMK
HAUS1
HDAC4
HGS
HOXB5
HOXB9
HTRA1
HYCC2
HYLS1
IFT20
IFT27
IGFN1
IHO1
IKZF3
IL16
INPP5J
IQCE
IQUB
ISCU
ITGB5
ITPKB
ITSN2
KANK2
KANSL1
KAT5
KDM1A
KIAA1217
KIFC3
KRT1
KRT18
KRT6A
KRT6B
KRT6C
KRT75
L3MBTL2
LASP1
LATS1
LCOR
LCP2
LENG1
LGALS3
LHX4
LIMS2
LIN7A
LINGO1
LMNB2
LMO1
LMO2
LMO3
LMO4
LYPLA1
LYSMD1
MAB21L2
MAGOH
MAGOHB
MBD3
MCM10
MCM7
MCRS1
MFAP1
MID2
MISP
MNAT1
MORF4L1
MORF4L2
MORN3
MOS
MSRB3
MTFR2
MVP
MYEF2
NCF2
NDC80
NDE1
NDEL1
NDN
NDUFA5
NEBL
NECAB2
NEFL
NME7
NOS3
NOTCH1
NSMF
NTAQ1
NUDT21
NXT2
OAS1
ODAD4
ORC1
PACRGL
PARD6B
PATL1
PCM1
PIAS2
PIBF1
PID1
PIK3R2
PIMREG
PIN1
PITX1
PKN1
PKN3
PKP1
PKP2
PKP4
PLAAT5
PLEKHA2
POLDIP3
POLR3C
POM121
POU4F3
PPP1R16B
PPP1R18
PPP2CA
PQBP1
PRAM1
PRKAA1
PRKAA2
PRKAB2
PRPF18
PRPF3
PRPF31
PSMA1
PSMA4
PTBP2
PTPN11
PTPN21
RAB1A
RAB1B
RAB2A
RAB2B
RAB33B
RAB39A
RAB39B
RAB6A
RAD18
RAMAC
RANBP3
RANBP3L
RBL1
RBM17
RBM22
RBM25
RBM39
RBM41
RCL1
RCOR3
RGS8
RHNO1
RHOJ
RIBC1
RIN1
RITA1
RNF135
RNF169
RNF213
RNF214
RNF6
RSPH14
RSRC2
RTP5
RUSC2
RXRB
SAMD4A
SAP30BP
SAXO4
SCAF8
SCEL
SCNM1
SECISBP2
SELENOV
SFI1
SH2D4A
SH3GLB2
SH3RF2
SHC3
SHISA6
SLU7
SLX9
SMARCB1
SMARCE1
SMCP
SMG9
SNAP47
SNF8
SNRPB
SNRPB2
SNRPC
SNTA1
SNW1
SNX18
SORBS2
SPATA18
SPATA2
SPATA22
SPG21
SRSF2
SSX2IP
STAC
STAMBPL1
STK25
STK26
STN1
SUDS3
SUGP2
SUPT5H
SYNPO2L
SYT17
SYT6
TBC1D22B
TBC1D30
TBP
TCEA2
TCEANC
TCF19
TCL1A
TDP2
TEAD4
TEPSIN
TEX9
TFAP4
TFIP11
THAP7
THYN1
TLE5
TMED2
TPM1
TPRX1
TPX2
TRAF1
TRAF3IP2
TRAF4
TRAF5
TRIM14
TRIM29
TRIM42
TSC1
TSC22D4
TSGA10
TSGA10IP
TSHZ2
TSHZ3
TSSC4
TSSK3
TTC23
TTC9C
TTPA
TUBGCP4
TXLNA
TXLNB
UBE2H
UBE2I
UBE2U
UBE3C
UBTFL1
USO1
USP15
USP2
UTP14C
UTP23
VPS28
VPS37C
WASHC3
WHRN
WT1
XIAP
YJU2
YTHDC1
ZBTB16
ZBTB4
ZBTB42
ZC2HC1C
ZFC3H1
ZFHX3
ZFP2
ZFYVE26
ZG16B
ZGPAT
ZMAT1
ZMAT2
ZNF124
ZNF250
ZNF280C
ZNF3
ZNF35
ZNF410
ZNF414
ZNF417
ZNF438
ZNF48
ZNF488
ZNF512B
ZNF524
ZNF572
ZNF581
ZNF587
ZNF594
ZNF648
ZNF688
ZNF774
ZNF835
ZZZ3
173 interacting genes:
ABCD3
ABI2
ABI3
ACTN1
ACTN2
AGR2
APIP
APP
BANF2
BLZF1
C22orf39
CABP5
CALCOCO2
CBS
CCDC102B
CCDC136
CCDC85B
CCNH
CDA
CDKN2D
CDR2
CEBPA
CEP70
CEP72
CFAP206
CHMP1A
CINP
CIP2A
COG4
COG6
COIL
CRX
CSTPP1
DCTD
DCTPP1
DDIT4L
DEF6
DLEU1
DRC12
DYDC1
DYNLT1
EHMT2
EIF4A3
EMSY
ERBB2
FNDC11
GNPTAB
GOLGA2
GOLGA6A
GPHN
GSDMD
GUCD1
HEXIM2
HOMER3
HOMEZ
HOOK2
HOXC11
HSD17B14
HSF2BP
IFT20
IKZF1
IKZF3
INO80E
IPO13
KAZN
KCTD1
KCTD13
KCTD17
KCTD6
KCTD7
KCTD9
KHDRBS3
KRT13
KRT15
KRT19
KRT31
KRT34
KRT37
KRT38
KRT40
KRTAP1-1
KRTAP1-3
KRTAP4-1
KRTAP5-9
KRTAP6-3
LDB1
LDOC1
LINC00632
LMO2
LONRF1
LZTFL1
LZTS1
LZTS2
MAD1L1
MAPK1
MAPRE1
MAPRE3
MCM6
MDH2
MID2
MIEF1
MKNK2
MKRN3
MLH1
MRFAP1L1
MSANTD4
MT-CO2
MTUS2
NAB2
NBPF19
NECAB2
NME7
NMI
NOP53
NOTCH2NLA
PCBD1
PCYT2
PICK1
PLK1
PM20D2
PNMA1
PNMA2
PNMA5
POLR1C
PPCDC
PRDM14
PRIMPOL
PRKN
PRPH
PSMA2
PSMA3
PSMA4
PSMA7
PSMB10
PSMB2
PSMB5
RAD54B
RBCK1
REL
RFC2
RGS19
ROPN1
SAT1
SFMBT1
SH3BP4
SH3GLB1
SLF2
SNCA
SPDEF
SSX2IP
TCF12
TCF4
TDO2
TEKT4
TNFAIP1
TNR
TRAF1
TRAF5
TRIM10
TRIM23
TRIM27
TRIM42
TRIM54
TSC22D4
UBD
UBXN11
VCP
VIM
VMAC
WTAP
YPEL5
ZFAND1
ZMYND19
Entrez ID
2801
5682
HPRD ID
03989
04170
Ensembl ID
ENSG00000167110
ENSG00000129084
Uniprot IDs
A0A8I5KNZ1
A0A8I5KZ68
A0A8I5QJQ7
A0A8J9BZL8
Q08379
B4E0X6
P25786
PDB IDs
4REY
6IW8
6IWA
6K06
4R3O
4R67
5A0Q
5GJQ
5GJR
5L4G
5LE5
5LEX
5LEY
5LEZ
5LF0
5LF1
5LF3
5LF4
5LF6
5LF7
5LN3
5M32
5T0C
5T0G
5T0H
5T0I
5T0J
5VFO
5VFP
5VFQ
5VFR
5VFS
5VFT
5VFU
6AVO
6E5B
6KWY
6MSB
6MSD
6MSE
6MSG
6MSH
6MSJ
6MSK
6R70
6REY
6RGQ
6WJD
6WJN
6XMJ
7AWE
7B12
7LXV
7NAN
7NAO
7NAP
7NAQ
7NHT
7PG9
7QXN
7QXP
7QXU
7QXW
7QXX
7QY7
7QYA
7QYB
7V5G
7V5M
7W37
7W38
7W39
7W3A
7W3B
7W3C
7W3F
7W3G
7W3H
7W3I
7W3J
7W3K
7W3M
8BZL
8CVR
8CVS
8CVT
8CXB
8JRI
8JRT
8JTI
8K0G
8QYJ
8QYL
8QYM
8QYN
8QYO
8QYS
8QZ9
8TM3
8TM4
8TM5
8TM6
8UD9
8USB
8USC
8YIX
8YIY
8YIZ
9E8G
9E8H
9E8I
9E8J
9E8K
9E8L
9E8N
9E8O
9E8Q
9HMN
Enriched GO Terms of Interacting Partners
?
Protein Binding
Nucleus
Nucleoplasm
Centrosome
Cytoskeleton
Spliceosomal Complex
Nuclear Speck
MRNA Processing
RNA Splicing
MRNA Splicing, Via Spliceosome
Regulation Of Nucleobase-containing Compound Metabolic Process
RNA Splicing, Via Transesterification Reactions
Cytoplasm
MRNA Metabolic Process
Nucleic Acid Metabolic Process
Regulation Of RNA Metabolic Process
Organelle Organization
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Nuclear Androgen Receptor Binding
RNA Metabolic Process
Microtubule-based Process
Zinc Ion Binding
Regulation Of Primary Metabolic Process
Spindle Pole
Regulation Of Transcription By RNA Polymerase II
Ciliary Basal Body
Cytoskeleton Organization
Centriole
Organelle Assembly
Negative Regulation Of RNA Metabolic Process
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Nuclear Export
Regulation Of Macromolecule Metabolic Process
Microtubule Cytoskeleton Organization
Negative Regulation Of DNA-templated Transcription
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Intermediate Filament Organization
Intermediate Filament Bundle Assembly
Regulation Of Gene Expression
Regulation Of Metabolic Process
RNA Processing
Negative Regulation Of Macromolecule Metabolic Process
Cilium Organization
Nucleobase-containing Compound Metabolic Process
Golgi Organization
U2-type Catalytic Step 2 Spliceosome
Identical Protein Binding
Protein Binding
Cytoskeleton
Intermediate Filament
Proteasome Core Complex
Keratin Filament
Intermediate Filament Organization
Structural Constituent Of Skin Epidermis
Cytoplasm
Supramolecular Fiber Organization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Organelle Organization
Proteasome Complex
Cytosol
Protein Homooligomerization
Proteasome Core Complex, Alpha-subunit Complex
Protein Complex Oligomerization
Cytoskeleton Organization
Protein Domain Specific Binding
Aggresome Assembly
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Serine/threonine Kinase Binding
Regulation Of Microtubule-based Process
Inclusion Body Assembly
Cytosine Metabolic Process
Structural Molecule Activity
Positive Regulation Of Protein K63-linked Deubiquitination
Cullin Family Protein Binding
Nucleus
Proteasome Core Complex, Beta-subunit Complex
Microtubule-based Process
Positive Regulation Of Organelle Organization
Ficolin-1-rich Granule Lumen
Regulation Of Microtubule Cytoskeleton Organization
Type III Intermediate Filament
Cellular Response To Arsenite Ion
Lung Goblet Cell Differentiation
Mitotic Spindle Astral Microtubule End
Protein Localization To Microtubule
Centrosome
Proteasomal Protein Catabolic Process
Cellular Component Assembly
Glial Cell Development
Mitotic Spindle Pole
Proteolysis Involved In Protein Catabolic Process
Pseudopodium
Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
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Tagcloud (Intersection)
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