GOLGA2 and AES

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GOLGA2	AES
Gene Name		golgin A2	amino-terminal enhancer of split
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Golgi Apparatus Cis-Golgi Network ER To Golgi Transport Vesicle Golgi Cisterna Membrane	Nucleus
	Molecular Function	Protein Binding Protein Kinase Binding Syntaxin Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Mitotic Cell Cycle Negative Regulation Of Protein Binding	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Transcription, DNA-templated Multicellular Organismal Development Organ Morphogenesis Negative Regulation Of Gene Expression Wnt Signaling Pathway Cellular Response To Extracellular Stimulus Negative Regulation Of Protein Binding Regulation Of Growth Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Response To Cytokine Stimulus Response To Interleukin-1 Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Anoikis
Pathways		Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase	APC truncation mutants have impaired AXIN binding misspliced GSK3beta mutants stabilize beta-catenin T41 mutants of beta-catenin aren't phosphorylated phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex AXIN missense mutants destabilize the destruction complex TCF7L2 mutants don't bind CTBP truncated APC mutants destabilize the destruction complex S45 mutants of beta-catenin aren't phosphorylated Signaling by Wnt repression of WNT target genes APC truncation mutants are not K63 polyubiquitinated S37 mutants of beta-catenin aren't phosphorylated Degradation of beta-catenin by the destruction complex deletions in the AMER1 gene destabilize the destruction complex AMER1 mutants destabilize the destruction complex S33 mutants of beta-catenin aren't phosphorylated AXIN mutants destabilize the destruction complex, activating WNT signaling deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling Signaling by WNT in cancer truncations of AMER1 destabilize the destruction complex
Drugs
Diseases
GWAS
Protein-Protein Interactions		281 interactors: ABLIM1 ADAP1 AES AFF4 ALKBH3 ALS2CR11 AMOTL2 ANKRD11 ANKRD36BP1 APC ARID5A ARL16 ARL4A ARNT2 ARPC3 ATP6V1C2 ATP6V1D ATP6V1G1 ATXN7 BAHD1 BARD1 BCAS2 BCL6B BMS1P5 BYSL C12orf50 C14orf105 C1orf109 C1orf35 C20orf195 CBX8 CCAR1 CCDC146 CCDC150 CCDC17 CCDC53 CCDC67 CCDC70 CCDC87 CCDC94 CCHCR1 CCNC CCNH CDC20B CDC5L CDC73 CDK1 CDK18 CDKL3 CENPP CEP57L1 CHCHD2 CHCHD3 CINP CORO1A CRMP1 CSPP1 CUL5 CYB5R2 DAXX DCTN4 DCX DDX6 DGCR6 DLGAP5 DLX6-AS1 DMTN DTX2 EIF3G EP300 EXOSC5 FAM110A FAM124B FAM126B FAM184A FAM193B FAM207A FAM214A FAM50B FAM90A1 FBF1 FBXL18 FBXO28 FIP1L1 GATA2 GATAD2B GCC1 GEM GFAP GLYCTK GNG5 GORASP1 GORASP2 GPANK1 GPKOW GPS2 GSE1 GTPBP10 GZMA GZMK HAUS1 HDAC4 HOXB9 HRASLS5 HTRA1 HYLS1 IFT20 IFT27 INPP5J IQCE ISCU ITPKB ITSN2 KANK2 KANSL1 KAT5 KDM1A KIAA1217 KIFC3 KRT18 KRT6A KRT6B KRT6C LASP1 LATS1 LCOR LCP2 LENG1 LGALS3 LIMS2 LIN7A LINGO1 LMO1 LMO2 LMO4 LYPLA1 LYSMD1 MAB21L2 MAGOH MAGOHB MBD3 MCM10 MCM7 MFAP1 MID2 MORF4L1 MORF4L2 MORN3 MOS MSRB3 MTFR2 MVP MYEF2 NCF2 NDE1 NDEL1 NDN NEBL NME7 NOS3 NUDT21 NXT2 ORC1 PARD6B PATL1 PIAS2 PID1 PIK3R2 PIN1 PKN1 PKP4 POLDIP3 POM121 PPP1R16B PPP1R18 PPP2CA PQBP1 PRKAA1 PRKAB2 PRPF31 PSMA1 PSMA4 RAB1A RAB1B RAB2A RAB2B RAB33B RAB39A RAB39B RAB6A RBL1 RBM17 RBM39 RBM41 RCOR3 RGS8 RHNO1 RIBC1 RITA1 RNF135 RNF213 RNF214 RSPH14 RSRC2 RTP5 RUSC2 SAMD4A SAP30BP SCAF8 SCEL SCNM1 SECISBP2 SELV SH2D4A SH3RF2 SHC3 SLU7 SMARCE1 SMCP SNAP47 SNF8 SNRPB SNRPB2 SNRPC SNTA1 SNW1 SPATA2 SPATA22 SRSF2 STAMBPL1 STK25 STK26 SYT6 TBP TCEA2 TCEANC TCF19 TCL1A TEAD4 TFAP4 THAP7 TMED2 TPM1 TPX2 TRIM29 TRIM42 TSC22D4 TSSC4 TSSK3 TTC23 TTC25 TTC9C TUBGCP4 TXLNA UBE2I UBE2U UBE3C USO1 USP2 UTP14C VPS28 VPS37C WDYHV1 YTHDC1 ZBTB16 ZFC3H1 ZFP2 ZFYVE26 ZGPAT ZMAT2 ZNF124 ZNF250 ZNF410 ZNF414 ZNF417 ZNF488 ZNF572 ZNF581 ZNF587 ZNF594 ZNF774	138 interactors: ABI2 AEN AR ARHGAP32 ATN1 BAHD1 BCL6 BHLHE40 BIRC7 BYSL C1orf109 C1orf216 C1orf94 C6orf165 CALCOCO2 CAPN1 CARD9 CCDC57 CCL7 CCNJL CCNK CIB3 CPSF7 CRACR2A CRX CTAGE5 DDX6 DGCR6 DIP2A EAF1 EIF4E2 FAM124A FAM124B FBF1 FOXP2 FRS3 FSD2 GABARAP GFAP GFI1B GOLGA2 GORASP2 GRB2 GTF2E1 HMGB1 HNF1A HNRNPF HOMEZ IKZF3 KANK2 KIFC3 KRT13 KRT15 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 L3MBTL2 LDOC1 LINC00526 LMO1 LMO2 LMO4 LSM2 MAGOHB MAPK14 MBNL1 MED31 MED4 MFAP1 MLX MORF4L2 MSX1 MTUS2 MVP MYO15B NAB2 NCDN NEK6 NOTCH2NL NUDT22 OLIG3 OSGIN1 PARVG POU2F1 PPP1R16A PRDM1 PRKAA1 PRKAA2 PRPF31 PRR3 PTRH2 QARS RBM10 RBPMS REL RELA RFX6 RHOXF2 RIMBP3 RNF31 RPL18A RUNX1 SCNM1 SDCBP SH3GL3 SIX1 SIX2 SIX3 SIX6 SKIL SMAD3 SNCAIP SNRPC SOX5 SRPK2 STK16 STX11 TBX3 TCF4 TMCC2 TRAF1 TRAF2 TRIM26 TRIM27 TRIM41 TSC22D4 TSGA10 TSSK3 U2AF2 UBXN11 VPS37B VPS37C ZBTB24 ZGPAT ZNF576
Entrez ID		2801	166
HPRD ID		03989	02556
Ensembl ID		ENSG00000167110	ENSG00000104964
Uniprot IDs		Q08379	Q08117 Q8WY48
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Cycle Organelle Organization Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process MRNA Metabolic Process MRNA Processing RNA Splicing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Mitotic Cell Cycle RNA Processing Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Metabolic Process Regulation Of Cellular Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Rab Protein Signal Transduction Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Cell Cycle Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Cellular Process Phagosome Maturation Chromosome Organization Cellular Component Assembly Chromatin Modification Chromatin Organization Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Phase Transition	RNA Metabolic Process Gene Expression Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Heterocycle Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Cellular Process Multicellular Organismal Development Cellular Metabolic Process Developmental Process Anatomical Structure Development Positive Regulation Of Cellular Biosynthetic Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Organ Morphogenesis Embryo Development Tissue Development RNA Processing RNA Splicing In Utero Embryonic Development Regulation Of Cell Death Organ Development
Tagcloud ?		5p accounts ameliorated ap1 canx chaperones clamp decoy deleterious deregulation disturbances electrical eliminated erg forced former h2o2 hek293 hsc70 micrornas mirnas myocytes patch reciprocal record seed sequestration trafficking upregulation	auger bonefit branemark depths differently friatec germany goteborg implants imz mannheim nobelpharma osseointegrated osseointegration outermost peaks photoelectron pure shifted spectroscopy speculated spray straumann sweden switzerland tio2 titanium waldenburg xps
Tagcloud (Difference) ?		5p accounts ameliorated ap1 canx chaperones clamp decoy deleterious deregulation disturbances electrical eliminated erg forced former h2o2 hek293 hsc70 micrornas mirnas myocytes patch reciprocal record seed sequestration trafficking upregulation	auger bonefit branemark depths differently friatec germany goteborg implants imz mannheim nobelpharma osseointegrated osseointegration outermost peaks photoelectron pure shifted spectroscopy speculated spray straumann sweden switzerland tio2 titanium waldenburg xps
Tagcloud (Intersection) ?