POLE4 and HSPA13

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		POLE4	HSPA13
Gene Name		polymerase (DNA-directed), epsilon 4, accessory subunit	heat shock protein 70kDa family, member 13
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Ada2/Gcn5/Ada3 Transcription Activator Complex Epsilon DNA Polymerase Complex	Endoplasmic Reticulum Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	DNA-directed DNA Polymerase Activity Protein Binding Sequence-specific DNA Binding Protein Heterodimerization Activity	ATP Binding
	Biological Process	Histone H3 Acetylation DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: HSPA13 NFYB POLE POLE2 POLE3 UBE3A	8 interactors: BAG6 POLE4 RMI1 SGTA SSR1 UBQLN1 UBQLN2 UBQLN4
Entrez ID		56655	6782
HPRD ID		16238	03061
Ensembl ID			ENSG00000155304
Uniprot IDs		Q9NR33	F5GWS8 P48723
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Biosynthetic Process Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Nuclear DNA Replication Telomere Maintenance Via Recombination Mitotic Recombination DNA Replication Telomere Maintenance Via Telomere Lengthening DNA Replication Initiation Transcription-coupled Nucleotide-excision Repair Telomere Maintenance Nucleotide-excision Repair DNA-dependent DNA Replication Sperm Entry G1/S Transition Of Mitotic Cell Cycle Chromosome Organization Error-prone Translesion Synthesis DNA Metabolic Process DNA Recombination Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Base-excision Repair, Gap-filling Translesion Synthesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA Synthesis Involved In DNA Repair Prostate Gland Growth Postreplication Repair Nucleobase-containing Compound Metabolic Process DNA Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Mitotic Cell Cycle Process Protein K48-linked Ubiquitination Cellular Homeostasis Cellular Nitrogen Compound Metabolic Process Androgen Receptor Signaling Pathway Protein Autoubiquitination Mitotic Cell Cycle Histone H3 Acetylation Cellular Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Base-excision Repair Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cellular Metabolic Process Ovarian Follicle Development Prostate Gland Development Intracellular Steroid Hormone Receptor Signaling Pathway	Response To Endoplasmic Reticulum Stress Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Reduction Of Food Intake In Response To Dietary Excess Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane Regulation Of Protein Metabolic Process Peptidyl-lysine Modification Protein Insertion Into ER Membrane
Tagcloud ?		acetylase acetylating ada ada2 ada3 atac chrac17 coregulators fam48a gcn5 hereafter invertebrates machineries map3 map3k7 mbip nc2beta p38ip paralogous pole3 saga spt spt20 spt3 staf36 staga taf9 wdr5 yeats2	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Difference) ?		acetylase acetylating ada ada2 ada3 atac chrac17 coregulators fam48a gcn5 hereafter invertebrates machineries map3 map3k7 mbip nc2beta p38ip paralogous pole3 saga spt spt20 spt3 staf36 staga taf9 wdr5 yeats2	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Intersection) ?