MAP2K1 and ARAF

  • Number of citations of the paper that reports this interaction (PMID 8157000)
  • 111
  • Data Source:
  • BioGRID (affinity chromatography technology, enzymatic study)
  • HPRD (in vitro)

MAP2K1

ARAF

Gene Name mitogen-activated protein kinase kinase 1 A-Raf proto-oncogene, serine/threonine kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 41 interactors: ARAF BANP BIRC6 BRAF CASP9 CDK5 CPNE1 CPNE4 EGFR ELK1 EP300 GRB10 HNRNPD HRAS KSR1 KSR2 LAMTOR3 MAP3K4 MAP3K8 MAPK1 MAPK14 MAPK3 MAPK8 MAPK8IP3 MYC PAK1 PARVA PEBP1 PEBP4 PLK3 PPARG PRKCI PRKCZ RAF1 RPS6KA2 RPS6KA4 SUMO1 TRAF3 TRAF6 TRIB1 WNK1 38 interactors: AGTRAP ASS1 BAD CHD6 COPS3 CPS1 CSNK2B DIDO1 E2F6 EFEMP1 GNA12 HRAS IRAK2 IRF7 KLHL12 KRAS MAP2K1 MAP2K2 MLH1 MYO18A NELFCD NUDT14 PBK PDGFRB PIK3R1 PKM PRPF6 RABGGTB RGS12 RRAS RRAS2 TEKT4P2 TESK1 TIMM44 TIRAP WNK1 YWHAG YWHAZ
Entrez ID 5604 369
HPRD ID 01469 02405
Ensembl ID ENSG00000078061
Uniprot IDs A4QPA9 B4DFY5 Q02750 B4DV85 P10398 Q96II5
PDB IDs 1S9J 2P55 3DV3 3DY7 3E8N 3EQB 3EQC 3EQD 3EQF 3EQG 3EQH 3EQI 3MBL 3ORN 3OS3 3PP1 3SLS 3V01 3V04 3VVH 3ZLS 3ZLW 3ZLX 3ZLY 3ZM4 4AN2 4AN3 4AN9 4ANB 4ARK 1WXM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actionable  adenocarcinomas  akt1  alk  braf  capture  ccdc6  cd74  clip4  deemed  driver  fusions  g719a  genomic  introns  kif5b  nccn  ngs  nras  pack  pik3ca  profiling  rearranged  ret  ros1  socs5  targetable  uniform  v600e 
al  augmentation  braf  craf1  die  differentiated  disruption  dramatically  drosophila  elegans  embryos  enlarged  establish  failed  finding  gestation  interacts  mek  membranes  mid  mutagenesis  programmed  ras  signalling  unlike  unpublished  vessels  w 
Tagcloud (Difference) ?
actionable  adenocarcinomas  akt1  alk  capture  ccdc6  cd74  clip4  deemed  driver  fusions  g719a  genomic  introns  kif5b  nccn  ngs  nras  pack  pik3ca  profiling  rearranged  ret  ros1  socs5  targetable  uniform  v600e 
al  augmentation  craf1  die  differentiated  disruption  dramatically  drosophila  elegans  embryos  enlarged  establish  failed  finding  gestation  interacts  mek  membranes  mid  mutagenesis  programmed  ras  signalling  unlike  unpublished  vessels  w 
Tagcloud (Intersection) ?
braf