MAP2K1 and HRAS

  • Number of citations of the paper that reports this interaction (PMID 7969158)
  • 23
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

MAP2K1

HRAS

Gene Name mitogen-activated protein kinase kinase 1 Harvey rat sarcoma viral oncogene homolog
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 41 interactors: ARAF BANP BIRC6 BRAF CASP9 CDK5 CPNE1 CPNE4 EGFR ELK1 EP300 GRB10 HNRNPD HRAS KSR1 KSR2 LAMTOR3 MAP3K4 MAP3K8 MAPK1 MAPK14 MAPK3 MAPK8 MAPK8IP3 MYC PAK1 PARVA PEBP1 PEBP4 PLK3 PPARG PRKCI PRKCZ RAF1 RPS6KA2 RPS6KA4 SUMO1 TRAF3 TRAF6 TRIB1 WNK1 78 interactors: AGTR1 ARAF ARHGEF1 BCL2 BRAF BRAP CAV1 CDC25A CDC25C DEAF1 DGKZ FNTA FNTB FYN GPSM2 GRB2 GRIN1 GRIN2D ICMT IKZF3 IL3 INSR IRAK1 IRAK2 ITSN1 KRT18 LGALS1 MAP2K1 MAPK8 MLLT4 NF1 PDE6D PDGFB PIK3CA PIK3CD PIK3CG PIK3R1 PLCE1 PRKCI PRKCZ RABAC1 RABGEF1 RAF1 RALA RALGDS RAP1B RAP1GDS1 RAPGEF1 RARRES3 RASA1 RASGRF1 RASGRP1 RASGRP4 RASIP1 RASSF1 RASSF2 RASSF5 RGL1 RGL2 RGL4 RGS12 RHOD RIN1 RIT2 RNF115 SHOC2 SNRPE SNX17 SOS1 SOS2 SRC TIAM1 TLR2 TLR9 TP73 TTC1 VAV1 ZBTB12
Entrez ID 5604 3265
HPRD ID 01469 01813
Ensembl ID ENSG00000174775
Uniprot IDs A4QPA9 B4DFY5 Q02750 P01112
PDB IDs 1S9J 2P55 3DV3 3DY7 3E8N 3EQB 3EQC 3EQD 3EQF 3EQG 3EQH 3EQI 3MBL 3ORN 3OS3 3PP1 3SLS 3V01 3V04 3VVH 3ZLS 3ZLW 3ZLX 3ZLY 3ZM4 4AN2 4AN3 4AN9 4ANB 4ARK 121P 1AA9 1AGP 1BKD 1CLU 1CRP 1CRQ 1CRR 1CTQ 1GNP 1GNQ 1GNR 1HE8 1IAQ 1IOZ 1JAH 1JAI 1K8R 1LF0 1LF5 1LFD 1NVU 1NVV 1NVW 1NVX 1P2S 1P2T 1P2U 1P2V 1PLJ 1PLK 1PLL 1Q21 1QRA 1RVD 1WQ1 1XCM 1XD2 1XJ0 1ZVQ 1ZW6 221P 2C5L 2CE2 2CL0 2CL6 2CL7 2CLC 2CLD 2EVW 2GDP 2LCF 2LWI 2Q21 2QUZ 2RGA 2RGB 2RGC 2RGD 2RGE 2RGG 2UZI 2VH5 2X1V 3DDC 3I3S 3K8Y 3K9L 3K9N 3KKM 3KKN 3KUD 3L8Y 3L8Z 3LBH 3LBI 3LBN 3LO5 3OIU 3OIV 3OIW 3RRY 3RRZ 3RS0 3RS2 3RS3 3RS4 3RS5 3RS7 3RSL 3RSO 3TGP 421P 4DLR 4DLS 4DLT 4DLU 4DLV 4DLW 4DLX 4DLY 4DLZ 4DST 4DSU 4EFL 4EFM 4EFN 4G0N 4G3X 4K81 4Q21 521P 5P21 621P 6Q21 721P 821P
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actionable  adenocarcinomas  akt1  alk  braf  capture  ccdc6  cd74  clip4  deemed  driver  fusions  g719a  genomic  introns  kif5b  nccn  ngs  nras  pack  pik3ca  profiling  rearranged  ret  ros1  socs5  targetable  uniform  v600e 
12th  arising  arose  carcinogenic  carrying  clustered  codon  contain  detectable  epithelium  find  fraction  gaa  gga  gland  indirectly  mammary  measure  methylurea  mutants  nitroso  nmu  organ  origin  preexisting  sectors  transition  untreated 
Tagcloud (Difference) ?
actionable  adenocarcinomas  akt1  alk  braf  capture  ccdc6  cd74  clip4  deemed  driver  fusions  g719a  genomic  introns  kif5b  nccn  ngs  nras  pack  pik3ca  profiling  rearranged  ret  ros1  socs5  targetable  uniform  v600e 
12th  arising  arose  carcinogenic  carrying  clustered  codon  contain  detectable  epithelium  find  fraction  gaa  gga  gland  indirectly  mammary  measure  methylurea  mutants  nitroso  nmu  organ  origin  preexisting  sectors  transition  untreated 
Tagcloud (Intersection) ?