MAP2K1 and BRAF

  • Number of citations of the paper that reports this interaction (PMID 8157000)
  • 111
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, in vivo)

MAP2K1

BRAF

Gene Name mitogen-activated protein kinase kinase 1 B-Raf proto-oncogene, serine/threonine kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to Vitamin E supplementation ( 22437554)
Protein-Protein Interactions 41 interactors: ARAF BANP BIRC6 BRAF CASP9 CDK5 CPNE1 CPNE4 EGFR ELK1 EP300 GRB10 HNRNPD HRAS KSR1 KSR2 LAMTOR3 MAP3K4 MAP3K8 MAPK1 MAPK14 MAPK3 MAPK8 MAPK8IP3 MYC PAK1 PARVA PEBP1 PEBP4 PLK3 PPARG PRKCI PRKCZ RAF1 RPS6KA2 RPS6KA4 SUMO1 TRAF3 TRAF6 TRIB1 WNK1 25 interactors: AKT1 BAD CCDC88A HRAS MAP2K1 MAP2K2 MAPK1 MRAS NEDD4L OIP5 PAK2 PRKACA PRKCE RAF1 RAP1A RAP1GAP RHEB RPS6KB2 SGK1 TERF1 YWHAB YWHAG YWHAH YWHAQ YWHAZ
Entrez ID 5604 673
HPRD ID 01469 01264
Ensembl ID ENSG00000157764
Uniprot IDs A4QPA9 B4DFY5 Q02750 P15056
PDB IDs 1S9J 2P55 3DV3 3DY7 3E8N 3EQB 3EQC 3EQD 3EQF 3EQG 3EQH 3EQI 3MBL 3ORN 3OS3 3PP1 3SLS 3V01 3V04 3VVH 3ZLS 3ZLW 3ZLX 3ZLY 3ZM4 4AN2 4AN3 4AN9 4ANB 4ARK 1UWH 1UWJ 2FB8 2L05 3C4C 3D4Q 3IDP 3II5 3NY5 3OG7 3PPJ 3PPK 3PRF 3PRI 3PSB 3PSD 3Q4C 3Q96 3SKC 3TV4 3TV6 4DBN 4E26 4E4X 4EHE 4EHG 4FK3 4G9C 4G9R 4H58 4JVG 4KSP 4KSQ 4MBJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actionable  adenocarcinomas  akt1  alk  braf  capture  ccdc6  cd74  clip4  deemed  driver  fusions  g719a  genomic  introns  kif5b  nccn  ngs  nras  pack  pik3ca  profiling  rearranged  ret  ros1  socs5  targetable  uniform  v600e 
al  araf  augmentation  craf1  die  differentiated  disruption  dramatically  drosophila  elegans  embryos  enlarged  establish  failed  finding  gestation  interacts  mek  membranes  mid  mutagenesis  programmed  ras  signalling  unlike  unpublished  vessels  w 
Tagcloud (Difference) ?
actionable  adenocarcinomas  akt1  alk  capture  ccdc6  cd74  clip4  deemed  driver  fusions  g719a  genomic  introns  kif5b  nccn  ngs  nras  pack  pik3ca  profiling  rearranged  ret  ros1  socs5  targetable  uniform  v600e 
al  araf  augmentation  craf1  die  differentiated  disruption  dramatically  drosophila  elegans  embryos  enlarged  establish  failed  finding  gestation  interacts  mek  membranes  mid  mutagenesis  programmed  ras  signalling  unlike  unpublished  vessels  w 
Tagcloud (Intersection) ?
braf