ARAF and NUDT14

Number of citations of the paper that reports this interaction (PMID 12620389)
9

Data Source:
HPRD (two hybrid)

		ARAF	NUDT14
Gene Name		A-Raf proto-oncogene, serine/threonine kinase	nudix (nucleoside diphosphate linked moiety X)-type motif 14
Image
Gene Ontology Annotations	Cellular Component	Cellular_component	Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Receptor Signaling Protein Activity Protein Binding ATP Binding Metal Ion Binding	Protein Binding UDP-sugar Diphosphatase Activity Metal Ion Binding ADP-ribose Diphosphatase Activity
	Biological Process	Cellular Protein Modification Process Protein Phosphorylation Regulation Of TOR Signaling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Peptidyl-serine Phosphorylation Intracellular Signal Transduction Negative Regulation Of Apoptotic Process	Metabolic Process
Pathways
Drugs		Adenosine triphosphate
Diseases
GWAS
Protein-Protein Interactions		38 interactors: AGTRAP ASS1 BAD CHD6 COPS3 CPS1 CSNK2B DIDO1 E2F6 EFEMP1 GNA12 HRAS IRAK2 IRF7 KLHL12 KRAS MAP2K1 MAP2K2 MLH1 MYO18A NELFCD NUDT14 PBK PDGFRB PIK3R1 PKM PRPF6 RABGGTB RGS12 RRAS RRAS2 TEKT4P2 TESK1 TIMM44 TIRAP WNK1 YWHAG YWHAZ	9 interactors: ARAF LNX1 NIF3L1 RAF1 REL TERF1 TERF2IP WDYHV1 ZCCHC10
Entrez ID		369	256281
HPRD ID		02405	14847
Ensembl ID		ENSG00000078061	ENSG00000183828
Uniprot IDs		B4DV85 P10398 Q96II5	B3KXY7 O95848
PDB IDs		1WXM	3Q91
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Immune Response-regulating Signaling Pathway Cellular Response To Stimulus Regulation Of Phosphorylation Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Kinase Activity Cellular Response To Peptide Hormone Stimulus Innate Immune Response Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Cell Motility Regulation Of Signal Transduction Cellular Response To Peptide Cellular Response To Organonitrogen Compound Immune Response Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Regulation Of Locomotion Fc-epsilon Receptor Signaling Pathway Regulation Of Cellular Component Movement Signaling Response To Hormone Regulation Of Signaling Cell Communication Toll-like Receptor 4 Signaling Pathway Fc Receptor Signaling Pathway Cellular Response To Hormone Stimulus Regulation Of Cell Migration Phosphorylation Response To Stimulus Regulation Of MAPK Cascade Response To Oleic Acid Intrinsic Apoptotic Signaling Pathway Response To Peptide Hormone Defense Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Immune Response Response To Peptide Positive Regulation Of Cell Motility Toll-like Receptor Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Cellular Component Movement Positive Regulation Of MAP Kinase Activity Cellular Response To Insulin Stimulus	Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Peptidyl-serine Phosphorylation Telomere Maintenance Death-inducing Signaling Complex Assembly Negative Regulation Of DNA Recombination At Telomere Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Regulation Of Peptidyl-serine Phosphorylation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Telomeric Loop Formation Age-dependent Telomere Shortening Dihydrobiopterin Metabolic Process Regulation Of Cell Death Regulation Of Proteolysis Cellular Metabolic Process Telomere Maintenance Via Telomere Shortening Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protection From Non-homologous End Joining At Telomere Regulation Of Intracellular Signal Transduction Regulation Of Proteasomal Protein Catabolic Process Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Intracellular Signal Transduction Regulation Of Chromosome Organization Regulation Of I-kappaB Kinase/NF-kappaB Signaling Replicative Cell Aging Protein Homooligomerization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Death Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Telomerase Activity DNA Replication Regulation Of Protein Metabolic Process Regulation Of Telomere Maintenance Via Telomerase Protein Complex Assembly Positive Regulation Of Interleukin-12 Biosynthetic Process Positive Regulation Of Microtubule Polymerization Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Telomerase Activity Regulation Of Protein Complex Assembly Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Proteolysis
Tagcloud ?		al augmentation braf craf1 die differentiated disruption dramatically drosophila elegans embryos enlarged establish failed finding gestation interacts mek membranes mid mutagenesis programmed ras signalling unlike unpublished vessels w
Tagcloud (Difference) ?		al augmentation braf craf1 die differentiated disruption dramatically drosophila elegans embryos enlarged establish failed finding gestation interacts mek membranes mid mutagenesis programmed ras signalling unlike unpublished vessels w
Tagcloud (Intersection) ?