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NKRF and HMOX2
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
NKRF
HMOX2
Description
NFKB repressing factor
heme oxygenase 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Specific Granule Membrane
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
ATPase Activator Activity
Nucleic Acid Binding
DNA Binding
RNA Binding
Protein Binding
Heme Oxygenase (decyclizing) Activity
Protein Binding
Oxidoreductase Activity
Heme Binding
Metal Ion Binding
Biological Process
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Response To Hypoxia
Heme Oxidation
Response To Oxidative Stress
Heme Catabolic Process
Pathways
Heme degradation
Neutrophil degranulation
RHOA GTPase cycle
Iron uptake and transport
Cytoprotection by HMOX1
Drugs
NADH
Stannsoporfin
Diseases
GWAS
Erectile dysfunction (
30583798
)
Interacting Genes
16 interacting genes:
ADARB1
DHX15
DHX58
FILNC1
HMOX2
KIFC1
NFKB1
NFKB2
PRKN
PRKRA
REL
RELA
STAU1
TARBP2
USP7
ZNF346
67 interacting genes:
A2M
APP
AQP6
ARL13B
ASGR2
ATP5F1B
BCL2L13
BIK
BLOC1S2
CCR2
CD79A
CEBPZ
CEP126
COPS6
CRB3
CSNK2A1
EBP
EEF1G
EIF3C
ELOVL4
ERGIC3
F2RL1
FAM209A
FAM210B
GET1
GIT1
GPR152
GPRASP1
GPX8
HAP1
IMMT
INPP5K
ITFG1
JADE1
KCNJ6
KCNMA1
LAPTM5
LRIF1
MED31
MGST3
MTNR1A
NDUFS2
NKRF
NR3C1
PCNT
PLXNB2
PTGER4
RBBP4
RETREG3
RNASEK
SAR1A
SETDB1
SGPL1
SHC1
SKA2
SLC30A8
SMO
SNX5
SNX7
SSMEM1
STOM
SYT1
TMEM14B
TMX2
VMA21
ZFP28
ZNF746
Entrez ID
55922
3163
HPRD ID
02341
00783
Ensembl ID
ENSG00000186416
ENSG00000103415
Uniprot IDs
A0AAG2UWQ9
A3F769
O15226
A0A087WT44
B3KSE0
P30519
PDB IDs
6SH6
6SH7
2Q32
2QPP
2RGZ
4WMH
5UC8
5UC9
5UCA
Enriched GO Terms of Interacting Partners
?
Double-stranded RNA Binding
Non-canonical NF-kappaB Signal Transduction
Negative Regulation Of Gene Expression
Canonical NF-kappaB Signal Transduction
Innate Immune Response
Response To Virus
Antiviral Innate Immune Response
NF-kappaB P50/p65 Complex
Defense Response To Symbiont
Defense Response To Other Organism
Positive Regulation Of Viral Genome Replication
I-kappaB/NF-kappaB Complex
Immune Response
Defense Response To Virus
NF-kappaB Complex
Response To External Biotic Stimulus
Immune System Process
Response To Stress
Response To Oxidative Stress
Regulation Of Retrograde Transport, Endosome To Golgi
Negative Regulation Of Macromolecule Metabolic Process
Cellular Response To Nicotine
Enzyme Binding
RISC-loading Complex
SiRNA Processing
Positive Regulation Of Viral Process
Pre-miRNA Binding
Response To Other Organism
Negative Regulation Of Metabolic Process
Cellular Response To Oxidative Stress
RISC Complex Assembly
Negative Regulation Of Macromolecule Biosynthetic Process
SiRNA Binding
Regulation Of Viral Genome Replication
Negative Regulation Of Kinase Activity
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Negative Regulation Of Biosynthetic Process
Actinin Binding
Pre-miRNA Processing
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Regulation Of Regulatory NcRNA Processing
Cellular Response To Angiotensin
Cellular Response To Interleukin-6
Cellular Response To Chemical Stress
Cytoplasmic Pattern Recognition Receptor Signaling Pathway
Defense Response
Regulation Of Viral Life Cycle
Response To Interleukin-6
Negative Regulation Of Phosphorylation
Membrane
Protein Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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