NKRF

Description		NFKB repressing factor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific ATPase Activator Activity Nucleic Acid Binding DNA Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: ADARB1 DHX15 DHX58 FILNC1 HMOX2 KIFC1 NFKB1 NFKB2 PRKN PRKRA REL RELA STAU1 TARBP2 USP7 ZNF346
Entrez ID		55922
HPRD ID		02341
Ensembl ID		ENSG00000186416
Uniprot IDs		A0AAG2UWQ9 A3F769 O15226
PDB IDs		6SH6 6SH7
Enriched GO Terms of Interacting Partners?		Double-stranded RNA Binding Non-canonical NF-kappaB Signal Transduction Negative Regulation Of Gene Expression Canonical NF-kappaB Signal Transduction Innate Immune Response Response To Virus Antiviral Innate Immune Response NF-kappaB P50/p65 Complex Defense Response To Symbiont Defense Response To Other Organism Positive Regulation Of Viral Genome Replication I-kappaB/NF-kappaB Complex Immune Response Defense Response To Virus NF-kappaB Complex Response To External Biotic Stimulus Immune System Process Response To Stress Response To Oxidative Stress Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Nicotine Enzyme Binding RISC-loading Complex SiRNA Processing Positive Regulation Of Viral Process Pre-miRNA Binding Response To Other Organism Negative Regulation Of Metabolic Process Cellular Response To Oxidative Stress RISC Complex Assembly Negative Regulation Of Macromolecule Biosynthetic Process SiRNA Binding Regulation Of Viral Genome Replication Negative Regulation Of Kinase Activity Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Biosynthetic Process Actinin Binding Pre-miRNA Processing Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Regulatory NcRNA Processing Cellular Response To Angiotensin Cellular Response To Interleukin-6 Cellular Response To Chemical Stress Cytoplasmic Pattern Recognition Receptor Signaling Pathway Defense Response Regulation Of Viral Life Cycle Response To Interleukin-6 Negative Regulation Of Phosphorylation
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