EAF2 and TCEA2

Number of citations of the paper that reports this interaction (PMID 12761297)
3

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		EAF2	TCEA2
Gene Name		ELL associated factor 2	transcription elongation factor A (SII), 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Elongation Factor Complex Nuclear Speck ELL-EAF Complex	Nucleoplasm Centrosome Transcription Elongation Factor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Transcription, DNA-templated Apoptotic Process Negative Regulation Of Cell Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development	DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BEND7 BIRC2 ELL TCEA1 TCEA2 TFPT TRIM23	47 interactors: ADAMTSL4 AKT1S1 ALAS1 APP BRCA1 CAMKV CCDC136 CCSER2 CDK11B CENPT CEP44 DAB1 DCAF10 DHRS2 DNAJB9 EAF2 EXOSC8 FAM9B FBF1 GOLGA2 GPKOW GRIPAP1 GTF2B KIAA1958 KRT40 KRTAP10-7 KRTAP5-9 LZTS2 MAGEA11 MARK3 MCM2 MEOX2 MID2 MKRN3 RPA1 SH3GL2 TAX1BP1 TAX1BP3 TCF4 TFCP2 THAP1 TNIP1 TRAF2 TRIM27 TRIM54 TSGA10 WDR47
Entrez ID		55840	6919
HPRD ID		09634	16069
Ensembl ID		ENSG00000145088	ENSG00000171703
Uniprot IDs		B4DWJ3 Q96CJ1	Q15560 Q6IB64 Q86VL0
PDB IDs			2LW4
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription, Elongation DNA-templated Transcription, Elongation Transcription, DNA-templated Positive Regulation Of Viral Transcription RNA Biosynthetic Process Transcription Elongation From RNA Polymerase II Promoter Regulation Of Viral Transcription Positive Regulation Of Viral Process Viral Process RNA Metabolic Process Positive Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Monoubiquitination Positive Regulation Of Protein K48-linked Ubiquitination Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Regulation Of Viral Process Translational Elongation Regulation Of Protein Monoubiquitination Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process SnRNA Transcription From RNA Polymerase III Promoter Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Transcription From RNA Polymerase II Promoter SnRNA Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Nitrogen Compound Metabolic Process SnRNA Transcription Positive Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Negative Regulation Of Necroptotic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Necrotic Cell Death Regulation Of RIG-I Signaling Pathway Regulation Of Necroptotic Process Negative Regulation Of Hydrolase Activity Positive Regulation Of Macromolecule Biosynthetic Process	Regulation Of Protein Binding Protein-DNA Complex Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Death Death Cell Cycle Negative Regulation Of Viral Process Protein Ubiquitination Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Signal Transduction Protein Modification By Small Protein Conjugation Cellular Macromolecular Complex Assembly Negative Regulation Of Signaling Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Cellular Component Assembly Regulation Of Binding Apoptotic Process DNA Strand Elongation Involved In DNA Replication Regulation Of Phosphorylation Programmed Cell Death Regulation Of Protein Kinase Activity Regulation Of Cellular Response To Heat DNA Strand Elongation Mitotic Cell Cycle Cell Cycle Process Protein K63-linked Ubiquitination Protein Trimerization Regulation Of Kinase Activity Positive Regulation Of Histone H4-K20 Methylation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Histone H4-K16 Acetylation Innate Immune Response Immune System Process Protein Autoubiquitination Regulation Of Viral Process Regulation Of Phosphorus Metabolic Process Response To Stress Cellular Response To Stress Protein Polyubiquitination Cerebellum Structural Organization Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Wnt Signaling Pathway Regulation Of Signal Transduction
Tagcloud ?		aberrant aim2 bh3 bik complements constitutive cooperates diffuse dlbcl expansion forkhead foxp1 harakiri lymphoid lymphoma lymphomagenesis lymphomas mucosa next oncogene proapoptotic promote rassf6 regarded relying represses repression tp53inp1 tp63
Tagcloud (Difference) ?		aberrant aim2 bh3 bik complements constitutive cooperates diffuse dlbcl expansion forkhead foxp1 harakiri lymphoid lymphoma lymphomagenesis lymphomas mucosa next oncogene proapoptotic promote rassf6 regarded relying represses repression tp53inp1 tp63
Tagcloud (Intersection) ?