DOK5 and BNIP3L

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DOK5	BNIP3L
Gene Name		docking protein 5	BCL2/adenovirus E1B 19kDa interacting protein 3-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Integral Component Of Membrane Intrinsic Component Of Membrane
	Molecular Function	Receptor Signaling Protein Activity Insulin Receptor Binding	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development	Viral Process Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Defense Response To Virus Mitochondrial Outer Membrane Permeabilization
Pathways
Drugs
Diseases
GWAS		Functional MRI ( 20215924)
Protein-Protein Interactions		9 interactors: BNIP3L CCDC85B EGFR IGF1R INSR NTRK2 NTRK3 OPRM1 RET	23 interactors: BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 DOK5 DUSP3 ECM1 EWSR1 FATE1 GBP2 GNB5 KLHL23 LDLRAD1 MAP1LC3A RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11
Entrez ID		55816	665
HPRD ID		16317	07288
Ensembl ID		ENSG00000101134	ENSG00000104765
Uniprot IDs		Q9P104	B0AZS9 B4DTN1 O60238 Q6IBV1
PDB IDs		1J0W
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Phosphorylation Positive Regulation Of MAPK Cascade Protein Autophosphorylation Regulation Of MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Protein Kinase B Signaling Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Digestive System Development Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-amino Acid Modification Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Organic Substance Exocrine System Development Regulation Of Cell Migration Response To Growth Factor Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Cell Motility Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of DNA Replication Regulation Of Phosphorylation Protein Phosphorylation Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Protein Kinase B Signaling Exocrine Pancreas Development Regulation Of Catalytic Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Positive Regulation Of Cell Proliferation Generation Of Neurons Positive Regulation Of Cellular Biosynthetic Process Neurogenesis Regulation Of Signal Transduction Positive Regulation Of Neurogenesis Regulation Of Intracellular Signal Transduction Male Sex Determination Regulation Of DNA Replication Negative Regulation Of Cell Death Phosphorylation	Mitochondrial Membrane Organization Mitochondrion Organization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Defense Response Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Neuron Death Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Mitochondrial Changes Response To External Stimulus Regulation Of Mitochondrion Organization Ovulation Cycle Process Negative Regulation Of Anoikis Positive Regulation Of Apoptotic Process Regulation Of Autophagy Female Gonad Development Positive Regulation Of Programmed Cell Death Ovulation Cycle Regulation Of Anoikis Development Of Primary Female Sexual Characteristics Positive Regulation Of Cell Death Regulation Of Response To DNA Damage Stimulus Response To Stress Defense Response To Protozoan Regulation Of Signal Transduction Response To Protozoan Response To Other Organism Release Of Cytochrome C From Mitochondria Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Biotic Stimulus Regulation Of Mitotic Cell Cycle Regulation Of Intracellular Signal Transduction Negative Regulation Of Mitochondrion Organization Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Regulation Of Signaling Positive Regulation Of Signal Transduction Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway Cellular Response To Organic Substance Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Calcium Ion Transport Membrane Organization Negative Regulation Of Calcium Ion Transport Cell Communication Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Apoptotic Process
Tagcloud ?		adrenal cdh11 combine copy dsc3 epigenomic etv1 exploration gnas h3k27 h3k27me3 h3k4me3 hoxa9 igf2 insm1 instance mark medulla methylations ntrk1 pheochromocytoma ptpre rassf2 ret silenced tgif1 tnfrsf10b trimethylase trimethylated	abrogates autophagy carried connections endoplasmic er extent hct116 interest ire1 microarray nbr1 nix p62 particular perk regulates reticulum sqstm1 stages still stress subjected transcriptional transmembrane unclear unfolded upr upregulation
Tagcloud (Difference) ?		adrenal cdh11 combine copy dsc3 epigenomic etv1 exploration gnas h3k27 h3k27me3 h3k4me3 hoxa9 igf2 insm1 instance mark medulla methylations ntrk1 pheochromocytoma ptpre rassf2 ret silenced tgif1 tnfrsf10b trimethylase trimethylated	abrogates autophagy carried connections endoplasmic er extent hct116 interest ire1 microarray nbr1 nix p62 particular perk regulates reticulum sqstm1 stages still stress subjected transcriptional transmembrane unclear unfolded upr upregulation
Tagcloud (Intersection) ?