DOK5 and RAI2

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		DOK5	RAI2
Description		docking protein 5	retinoic acid induced 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Differentiation Positive Regulation Of MAPK Cascade Regulation Of Neurotrophin TRK Receptor Signaling Pathway	Embryo Development Ending In Birth Or Egg Hatching Animal Organ Development
Pathways		RET signaling
Drugs
Diseases
GWAS		Celiac disease ( 23936387) Erectile dysfunction ( 30583798) Functional MRI ( 20215924) HDL cholesterol levels in HIV infection ( 33109212)	Prostate-specific antigen levels ( 28139693)
Interacting Genes		20 interacting genes: AHDC1 ATF3 BNIP3L CCDC85B CDCA4 DOK3 EGFR FANCG IGF1R INSR NTRK2 NTRK3 OLIG1 OPRM1 PFDN5 RAI2 RET SCOC TSC1 WIZ	13 interacting genes: APP APPL2 ATXN1 CTBP1 CTBP2 DOK5 FHL2 FXR2 SGTB TRIM55 TRIM63 UBQLN1 UBQLN4
Entrez ID		55816	10742
HPRD ID		16317	02199
Ensembl ID		ENSG00000101134	ENSG00000131831
Uniprot IDs		Q9P104	B2RBE9 B3KPD7 Q9Y5P3
PDB IDs		1J0W	8ARI 8ATI
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activity Receptor Complex Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Insulin Receptor Activity Axon Regulation Of Metabolic Process Enzyme-linked Receptor Protein Signaling Pathway Insulin Receptor Complex Neurotrophin Receptor Activity Neurotrophin Binding Insulin Binding Protein Kinase Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Kinase Activity Dendritic Spine Maintenance Action Potential Propagation Neuronal Action Potential Propagation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Insulin-like Growth Factor I Binding Insulin Receptor Substrate Binding Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Endosome Phosphatidylinositol 3-kinase Binding Myelination Axon Ensheathment Myelination In Peripheral Nervous System Learning Or Memory Positive Regulation Of Cell Junction Assembly Cellular Response To Growth Factor Stimulus Endosome Membrane Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Nervous System Process Protein Autophosphorylation Amyloid-beta Clearance Mechanoreceptor Differentiation Cognition Positive Regulation Of Cell Motility Response To Growth Factor Positive Regulation Of Cell Population Proliferation Neurotrophin Signaling Pathway Positive Regulation Of Locomotion	Identical Protein Binding Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process White Fat Cell Differentiation Viral Genome Replication Regulation Of Signal Transduction Regulation Of Long-term Neuronal Synaptic Plasticity Nucleus Negative Regulation Of Macromolecule Metabolic Process NAD Binding Amyloid-beta Complex Protein Homooligomerization Growth Cone Lamellipodium Postsynapse Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Negative Regulation Of Transcription By RNA Polymerase II Amylin Binding Positive Regulation Of Toll Signaling Pathway Visual Learning Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Cytoplasm Transcription Corepressor Activity Transcription Coregulator Binding Transcription Corepressor Binding Negative Regulation Of Store-operated Calcium Channel Activity Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Regulation Of Neuronal Synaptic Plasticity Regulation Of Primary Metabolic Process Protein Complex Oligomerization Negative Regulation Of Biosynthetic Process Visual Behavior Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Transcription Repressor Complex Regulation Of Carbohydrate Catabolic Process Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Atrial Cardiac Muscle Cell Development Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation TRC Complex Positive Regulation Of Macropinocytosis Nuclear Proteasome Complex Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of ATP Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?