TMA16 and KLHL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TMA16	KLHL2
Gene Name		translation machinery associated 16 homolog (S. cerevisiae)	kelch-like family member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function		Actin Binding Protein Binding
	Biological Process		Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP IKBKG KLHL2 KRTAP10-7 NEDD4L	15 interactors: ACTC1 BCAM CCDC43 CLK2 CUL3 KLHL12 SDCBP TMA16 TNPO2 TXNDC12 UBE2C UBE2D1 WNK1 WNK4 ZNF114
Entrez ID		55319	11275
HPRD ID		07739	09311
Ensembl ID		ENSG00000198498	ENSG00000109466
Uniprot IDs		Q96EY4	O95198
PDB IDs			2XN4
Enriched GO Terms of Interacting Partners?		Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Intracellular Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Positive Regulation Of Protein Metabolic Process Homeostatic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Axon Choice Point Recognition Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Tight Junction Assembly Neuron Remodeling Cellular Metal Ion Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Sodium Ion Transport Cellular Cation Homeostasis Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Sodium Ion Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Regulation Of Protein Metabolic Process Cellular Chemical Homeostasis Ventricular Cardiac Muscle Cell Action Potential Cellular Copper Ion Homeostasis Viral Process Ion Homeostasis Regulation Of Protein Localization To Cell Surface Protein Ubiquitination Negative Regulation Of Potassium Ion Transport Negative Regulation Of Systemic Arterial Blood Pressure Regulation Of Membrane Repolarization Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Copper Ion Homeostasis Suckling Behavior Protein Modification By Small Protein Conjugation Sodium Ion Homeostasis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cardiac Muscle Cell Action Potential Involved In Contraction Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Cellular Homeostasis	Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Pancreatic Juice Secretion Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Segregation Negative Regulation Of Transferase Activity Regulation Of Mitotic Nuclear Division COPII Vesicle Coating Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process COPII-coated Vesicle Budding Positive Regulation Of Cellular Protein Catabolic Process Protein Polyubiquitination Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Vesicle Targeting, To, From Or Within Golgi Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Assembly Checkpoint Regulation Of Chromosome Organization Spindle Assembly Checkpoint Protein K48-linked Ubiquitination Negative Regulation Of Protein Kinase Activity Positive Regulation Of Protein Catabolic Process Protein Ubiquitination Mitotic Spindle Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Mitotic Nuclear Division Protein Monoubiquitination Localization Within Membrane Negative Regulation Of Chromosome Segregation Vesicle Targeting Regulation Of Cell Cycle Phase Transition Negative Regulation Of Kinase Activity Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Spindle Checkpoint Negative Regulation Of Mitotic Nuclear Division Regulation Of Cell Division Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Proteolysis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Protein Phosphorylation Negative Regulation Of Catalytic Activity Cellular Protein Modification Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity
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