MAPK8IP2 and ZNF593

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		MAPK8IP2	ZNF593
Description		mitogen-activated protein kinase 8 interacting protein 2	zinc finger protein 593
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GO Annotations	Cellular Component	Cytoplasm Postsynaptic Density Protein-containing Complex Neuronal Cell Body	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Amyloid-beta Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding JUN Kinase Binding Kinesin Binding Protein Kinase Binding Protein Kinase Activator Activity Protein-containing Complex Binding	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Ribonucleoprotein Complex Binding Metal Ion Binding Preribosome Binding
	Biological Process	MAPK Cascade Behavioral Fear Response Signal Complex Assembly JNK Cascade Mating Behavior Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Modulation Of Excitatory Postsynaptic Potential Negative Regulation Of Apoptotic Signaling Pathway	Ribosome Biogenesis Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Pathways
Drugs
Diseases
GWAS		Cutaneous leishmaniasis ( 32830257) Gut microbiota relative abundance (Prevotella) ( 33208821) Hip circumference ( 28552196)
Interacting Genes		86 interacting genes: ADRB2 AFG3L2 ANAPC10 APP ASRGL1 BBS10 C1QTNF3 C22orf39 C8orf33 CFL1 CHN1 CRMP1 CRP CTNNBL1 DUSP16 DUSP18 EGFR ERBB2 ERG28 EZH2 FGF12 FGF13 FSCN1 GALNT3 GBP2 HLA-C HOXC8 IGIP ING4 ITSN1 KIFC2 KLC1 LEFTY2 LRP1 LRP2 LRP8 LSM8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 MNDA MRE11 MSRB3 NDUFS6 NUMB PLXNA3 POLR1H PRSS23 RAI1 RBM4 RBX1 RPS6KB2 RSPH1 RYBP SCLT1 SH2D1B SLC39A13 SLPI SMARCB1 SMS SPINK2 SPSB3 SRP19 SYNE2 TARBP2 TIAM1 TMEM128 TP53BP2 UNC119 USP46 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF670 ZNF784	10 interacting genes: DDIT4L GPR3 LNX1 MAP3K20 MAP3K7 MAPK8IP2 PICK1 POLR1H RAB1A SRPK2
Entrez ID		23542	51042
HPRD ID		09674	15866
Ensembl ID		ENSG00000008735	ENSG00000142684
Uniprot IDs		Q13387	O00488
PDB IDs		8RPP	1ZR9 6LSS 6LU8 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8IDT 8IDY 8IE3 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR3 8RL2
Enriched GO Terms of Interacting Partners?		MAPK Cascade JNK Cascade Intracellular Signaling Cassette Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process JUN Kinase Activity Regulation Of Apoptotic Process Growth Cone Regulation Of Programmed Cell Death Cellular Senescence MAP Kinase Activity Positive Regulation Of MAPK Cascade Regulation Of MAPK Cascade Response To Light Stimulus MAP Kinase Kinase Kinase Activity Fc-epsilon Receptor Signaling Pathway Protein Kinase Activity Signal Transduction Protein Serine Kinase Activity Positive Regulation Of JNK Cascade Regulation Of Cellular Component Organization Positive Regulation Of Protein Modification Process Regulation Of MAP Kinase Activity JUN Kinase Binding Regulation Of Cell Communication Regulation Of Intracellular Signal Transduction Cellular Response To Oxygen-containing Compound Positive Regulation Of Phosphate Metabolic Process Clathrin-coated Pit Hippocampus Development Positive Regulation Of MAP Kinase Activity Regulation Of Protein Kinase Activity Protein Serine/threonine Kinase Activity Regulation Of Kinase Activity Perinuclear Region Of Cytoplasm Regulation Of Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Low-density Lipoprotein Particle Receptor Activity MAP Kinase Kinase Activity Receptor Complex Kinase Activity Kinesin Binding Regulation Of Signaling Response To Radiation Positive Regulation Of Kinase Activity Regulation Of Voltage-gated Sodium Channel Activity Positive Regulation Of Apoptotic Process Apolipoprotein Binding Regulation Of Protein Modification Process Regulation Of JNK Cascade	JNK Cascade Phosphorylation Protein Phosphorylation P38MAPK Cascade Stress-activated MAPK Cascade MAP Kinase Kinase Kinase Activity Stress-activated Protein Kinase Signaling Cascade Magnesium Ion Binding Regulation Of Stress-activated Protein Kinase Signaling Cascade Protein Kinase Activator Activity MAPK Cascade Positive Regulation Of Mitotic DNA Damage Checkpoint Mannosyltransferase Complex Defense Response Phosphate-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Protein Serine Kinase Activity Alpha-1,6-mannosyltransferase Activity Intracellular Signaling Cassette Protein Serine/threonine Kinase Activity Negative Regulation Of Signaling I-kappaB Phosphorylation Linear Polyubiquitin Binding Negative Regulation Of Cell Communication Termination Of RNA Polymerase I Transcription Negative Regulation Of Translation In Response To Endoplasmic Reticulum Stress GPI Mannosyltransferase Activity
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