MAPK8IP2 and ASRGL1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MAPK8IP2	ASRGL1
Gene Name		mitogen-activated protein kinase 8 interacting protein 2	asparaginase like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Neuronal Cell Body Protein Complex Neuronal Postsynaptic Density	Nucleus Cytoplasm
	Molecular Function	Beta-amyloid Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding Kinesin Binding Protein Kinase Binding Protein Kinase Activator Activity Protein Complex Binding	N4-(beta-N-acetylglucosaminyl)-L-asparaginase Activity Asparaginase Activity Beta-aspartyl-peptidase Activity
	Biological Process	MAPK Cascade Behavioral Fear Response Signal Complex Assembly JNK Cascade Mating Behavior Regulation Of Receptor Activity Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Positive Regulation Of Protein Kinase Activity Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity	Proteolysis Asparagine Catabolic Process Via L-aspartate
Pathways
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326)
Protein-Protein Interactions		52 interactors: ADRB2 AFG3L2 APP ASRGL1 BBS10 C14orf1 CFL1 CHN1 CRMP1 DUSP16 EGFR ERBB2 EZH2 FGF12 FSCN1 GBP2 ITSN1 KIFC2 KLC1 LRP1 LRP2 LRP8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 NDUFS6 PLXNA3 PRSS23 RAI1 RBX1 RPS6KB2 SMARCB1 SMS SYNE2 TIAM1 TP53BP2 UNC119 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF784	4 interactors: GSK3B MAP2K5 MAPK8IP2 TAB1
Entrez ID		23542	80150
HPRD ID		09674	07006
Ensembl ID		ENSG00000008735	ENSG00000162174
Uniprot IDs		Q13387	Q7L266
PDB IDs			3TKJ 4ET0 4GDT 4GDU 4GDV 4GDW 4HLO 4HLP
Enriched GO Terms of Interacting Partners?		Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade JNK Cascade Signal Transduction By Phosphorylation MAPK Cascade Regulation Of Protein Kinase Activity Regulation Of MAPK Cascade Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Kinase Activity JUN Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of MAP Kinase Activity Response To Stress Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of MAPK Cascade Regulation Of Signal Transduction Response To Light Stimulus Response To External Stimulus Response To Radiation Regulation Of Signaling Intracellular Signal Transduction Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Axon Guidance Regulation Of Intracellular Signal Transduction Signal Transduction Axonogenesis Phosphorylation Cell Part Morphogenesis Axon Development Response To Stimulus Cell Morphogenesis Involved In Neuron Differentiation Response To Abiotic Stimulus Protein Phosphorylation Cellular Response To Stress Signaling	Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process MAPK Cascade Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Cellular Response To Stress Positive Regulation Of Catalytic Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Kinase Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Protein Metabolic Process JNK Cascade Regulation Of Catalytic Activity Positive Regulation Of Cellular Metabolic Process Stress-activated MAPK Cascade Positive Regulation Of Cell Growth Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Activation Of MAPK Activity Enzyme Linked Receptor Protein Signaling Pathway Phosphate-containing Compound Metabolic Process Regulation Of Signaling Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production ERK5 Cascade Superior Temporal Gyrus Development Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of MAP Kinase Activity Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Neurotrophin TRK Receptor Signaling Pathway
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