MAPK8IP2 and NDUFS6

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MAPK8IP2	NDUFS6
Gene Name		mitogen-activated protein kinase 8 interacting protein 2	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Neuronal Cell Body Protein Complex Neuronal Postsynaptic Density	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	Beta-amyloid Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding Kinesin Binding Protein Kinase Binding Protein Kinase Activator Activity Protein Complex Binding	NADH Dehydrogenase (ubiquinone) Activity Electron Carrier Activity
	Biological Process	MAPK Cascade Behavioral Fear Response Signal Complex Assembly JNK Cascade Mating Behavior Regulation Of Receptor Activity Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Positive Regulation Of Protein Kinase Activity Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity	Mitochondrial Electron Transport, NADH To Ubiquinone Fatty Acid Metabolic Process Muscle Contraction Multicellular Organismal Aging Respiratory Electron Transport Chain Multicellular Organism Growth Cellular Metabolic Process Small Molecule Metabolic Process Reproductive System Development Mitochondrion Morphogenesis Cardiovascular System Development
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs			NADH
Diseases
GWAS
Protein-Protein Interactions		52 interactors: ADRB2 AFG3L2 APP ASRGL1 BBS10 C14orf1 CFL1 CHN1 CRMP1 DUSP16 EGFR ERBB2 EZH2 FGF12 FSCN1 GBP2 ITSN1 KIFC2 KLC1 LRP1 LRP2 LRP8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 NDUFS6 PLXNA3 PRSS23 RAI1 RBX1 RPS6KB2 SMARCB1 SMS SYNE2 TIAM1 TP53BP2 UNC119 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF784	5 interactors: FGFR3 KCNH2 MAP3K7 MAPK6 MAPK8IP2
Entrez ID		23542	4726
HPRD ID		09674	10356
Ensembl ID		ENSG00000008735
Uniprot IDs		Q13387	O75380 Q6IBC4
PDB IDs
Enriched GO Terms of Interacting Partners?		Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade JNK Cascade Signal Transduction By Phosphorylation MAPK Cascade Regulation Of Protein Kinase Activity Regulation Of MAPK Cascade Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Kinase Activity JUN Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of MAP Kinase Activity Response To Stress Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of MAPK Cascade Regulation Of Signal Transduction Response To Light Stimulus Response To External Stimulus Response To Radiation Regulation Of Signaling Intracellular Signal Transduction Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Axon Guidance Regulation Of Intracellular Signal Transduction Signal Transduction Axonogenesis Phosphorylation Cell Part Morphogenesis Axon Development Response To Stimulus Cell Morphogenesis Involved In Neuron Differentiation Response To Abiotic Stimulus Protein Phosphorylation Cellular Response To Stress Signaling	Signal Transduction By Phosphorylation MAPK Cascade Phosphorylation Intracellular Signal Transduction Phosphate-containing Compound Metabolic Process Protein Phosphorylation Positive Regulation Of MAPK Cascade Positive Regulation Of Kinase Activity Positive Regulation Of Transferase Activity JNK Cascade Regulation Of MAPK Cascade Negative Regulation Of Potassium Ion Export Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Membrane Depolarization Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of Heart Rate By Hormone Positive Regulation Of Phosphorylation Regulation Of JNK Cascade Positive Regulation Of Protein Modification Process Cell-cell Signaling Signal Transduction Peptidyl-amino Acid Modification Regulation Of Stress-activated MAPK Cascade Signaling Regulation Of Protein Phosphorylation Cell Communication Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Nonassociative Learning Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Alveolar Secondary Septum Development Fc Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Membrane Potential Axonogenesis Involved In Innervation Positive Regulation Of Signal Transduction Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Modification Process Regulation Of Phosphorylation Defense Response Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Cellular Response To Stimulus Chondrocyte Proliferation Peptidyl-histidine Phosphorylation
Tagcloud ?			abnormality albuminuria cystatin defects defence deficiency electrochemical excretion f2t glomerular gt hallmarks impairment inner innovation interruption isoprostane juvenile kim mitochondrial modest nitrotyrosine oxidized partial renal respiratory se superoxide
Tagcloud (Difference) ?			abnormality albuminuria cystatin defects defence deficiency electrochemical excretion f2t glomerular gt hallmarks impairment inner innovation interruption isoprostane juvenile kim mitochondrial modest nitrotyrosine oxidized partial renal respiratory se superoxide
Tagcloud (Intersection) ?