ANKZF1 and CTTN

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		ANKZF1	CTTN
Gene Name		ankyrin repeat and zinc finger domain containing 1	cortactin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane	Ruffle Cytoplasm Cytoskeleton Actin Filament Coated Pit Focal Adhesion Cell Cortex Voltage-gated Potassium Channel Complex Lamellipodium Growth Cone Cortical Cytoskeleton Dendritic Spine Extracellular Vesicular Exosome Mitotic Spindle Midzone
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process		Intracellular Protein Transport Receptor-mediated Endocytosis Substrate-dependent Cell Migration, Cell Extension Actin Filament Polymerization Regulation Of Axon Extension Positive Regulation Of Actin Filament Polymerization Actin Cytoskeleton Reorganization Focal Adhesion Assembly Neuron Projection Morphogenesis Cell Motility Dendritic Spine Maintenance Lamellipodium Organization Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APP AURKB CA2 CTTN DNAJB11 NRSN2 STAT6	36 interactors: ACD ACTA1 ACTG1 ACTR2 ACTR3 ANKZF1 ARHGAP17 ARHGAP8 CASP3 CD2AP CHD3 CTNND1 CTNND2 CTTNBP2 DNM1 DNM2 FER FGD1 GRB2 HAX1 HDAC6 HIP1R KCNA2 MET MYLK SDC3 SHANK2 SIRT1 SPRR2A SRC SYK TINF2 TJP1 TNK2 WASL WIPF1
Entrez ID		55139	2017
HPRD ID		07673	01268
Ensembl ID		ENSG00000163516	ENSG00000085733
Uniprot IDs		Q9H8Y5	Q14247 Q53HG7
PDB IDs			1X69 2D1X
Enriched GO Terms of Interacting Partners?		T-helper 1 Cell Lineage Commitment Synaptic Growth At Neuromuscular Junction Positive Regulation Of Dipeptide Transmembrane Transport Regulation Of Protein Binding Histone H3-S28 Phosphorylation Collateral Sprouting In Absence Of Injury Positive Regulation Of Cellular PH Reduction Interleukin-4-mediated Signaling Pathway Spindle Stabilization Regulation Of Chloride Transport Positive Regulation Of Isotype Switching To IgE Isotypes Collateral Sprouting Axon Midline Choice Point Recognition Abscission Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Cell Cycle Process Axon Choice Point Recognition Mitotic Spindle Midzone Assembly Cleavage Furrow Formation Mitotic Spindle Elongation T-helper Cell Lineage Commitment Angiotensin-activated Signaling Pathway Dendritic Spine Maintenance Regulation Of Binding T-helper 1 Cell Differentiation Negative Regulation Of Cytokinesis CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Neuron Remodeling Protein Localization To Kinetochore Positive Regulation Of Cell Cycle Anatomical Structure Morphogenesis Response To Abiotic Stimulus Substrate-dependent Cell Migration, Cell Extension Spindle Midzone Assembly Regulation Of Developmental Growth Negative Regulation Of B Cell Apoptotic Process Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Chromosome, Centromeric Region Negative Regulation Of Type 2 Immune Response Cell Adhesion Response To Light Stimulus Cellular Protein Complex Assembly Mammary Gland Epithelial Cell Proliferation Positive Regulation Of Synaptic Transmission, GABAergic Multicellular Organismal Development Positive Regulation Of Bone Resorption Cellular Response To Reactive Nitrogen Species Histone-serine Phosphorylation Cellular Response To Fluid Shear Stress Positive Regulation Of Isotype Switching	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Endocytosis Fc Receptor Signaling Pathway Cellular Response To Stimulus Cellular Component Assembly Regulation Of Cellular Component Organization Actin Cytoskeleton Organization Actin Filament-based Process Anatomical Structure Development Response To External Stimulus Developmental Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Organelle Organization Phagocytosis Cell Communication Positive Regulation Of Organelle Organization Multicellular Organismal Development Immune Response-activating Cell Surface Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Organelle Organization Movement Of Cell Or Subcellular Component Chemotaxis Immune Response-regulating Signaling Pathway System Development Signaling Cytoskeleton Organization Signal Transduction Positive Regulation Of Immune System Process Response To Stimulus Cell Projection Organization Cell Morphogenesis Involved In Differentiation Axon Guidance Locomotion Innate Immune Response Positive Regulation Of Protein Complex Assembly Regulation Of Immune System Process Cell Morphogenesis Actin Filament Organization Positive Regulation Of Immune Response Neuron Projection Morphogenesis Positive Regulation Of Cellular Component Biogenesis Regulation Of Immune Response Peptidyl-tyrosine Autophosphorylation Regulation Of Protein Complex Assembly Positive Regulation Of Cytoskeleton Organization
Tagcloud ?			applicability csmd1 delineate emphasized fadd fgf4 fhit floor gains gata4 imbalances individualized losses mandatory mccc1 mlpa mouth mtus1 multiplex p428 panel probe probemix propensity ptk2 rarb relapses tier wisp1
Tagcloud (Difference) ?			applicability csmd1 delineate emphasized fadd fgf4 fhit floor gains gata4 imbalances individualized losses mandatory mccc1 mlpa mouth mtus1 multiplex p428 panel probe probemix propensity ptk2 rarb relapses tier wisp1
Tagcloud (Intersection) ?