ANKZF1

Description		ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane
	Molecular Function	Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding Catalytic Activity, Acting On A TRNA
	Biological Process	TRNA 3'-terminal CCA Addition Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins ERAD Pathway TRNA 3'-end Processing Cellular Response To Hydrogen Peroxide Rescue Of Stalled Ribosome
Pathways		Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: APP AURKB CA2 CRK CTTN DNAJB11 NRSN2 STAT6 UBC YWHAE
Entrez ID		55139
HPRD ID		07673
Ensembl ID		ENSG00000163516
Uniprot IDs		B8ZZS4 Q9H8Y5
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Yeast Mitotic Spindle Midzone Regulation Of Immune Response Ephrin Receptor Binding Positive Regulation Of Supramolecular Fiber Organization Regulation Of Innate Immune Response Neuron Projection Organization Regulation Of Toll-like Receptor Signaling Pathway Response To Nerve Growth Factor Dendrite Development Cellular Response To Nerve Growth Factor Stimulus Negative Regulation Of Immune Response Negative Regulation Of Immune System Process Regulation Of T Cell Migration Acetylcholine Receptor Activator Activity Amyloid-beta Complex Regulation Of Defense Response Growth Cone Lamellipodium Regulation Of Immune System Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Lymphocyte Migration Clathrin-coated Pit Response To Fungus Lipoprotein Particle Positive Regulation Of Protein Import Positive Regulation Of Dipeptide Transmembrane Transport Cyanamide Hydratase Activity Helper T Cell Diapedesis Cerebral Cortex Development Hippocampus Development Signaling Adaptor Activity Protein Phosphorylated Amino Acid Binding Ubiquitin Protein Ligase Binding Scaffold Protein Binding Response To Cholecystokinin Mammary Gland Morphogenesis Regulation Of Heart Rate By Hormone Mitotic Sister Chromatid Biorientation Repair Of Mitotic Kinetochore Microtubule Attachment Defect Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Supramolecular Fiber Organization PTB Domain Binding Signaling Receptor Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Monoatomic Cation Homeostasis Regulation Of Monoatomic Ion Transport Enzyme Binding
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