CMTM6 and SUMO2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CMTM6	SUMO2
Gene Name		CKLF-like MARVEL transmembrane domain containing 6	small ubiquitin-like modifier 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm PML Body
	Molecular Function	Cytokine Activity	Protein Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding
	Biological Process	Chemotaxis	Protein Sumoylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			SUMO is proteolytically processed Post-translational protein modification SUMOylation SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) Processing and activation of SUMO
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ATP13A2 DNMT3B DUSP10 FAM9B PPBP SUMO2 XRCC6	91 interactors: ALAS1 ARL13A ARNTL ATXN1 ATXN7 AURKB BAD BCL11A BLM BRCC3 BRE C18orf25 CCNE2 CDCA8 CENPC CHAF1A CHD3 CMTM6 CORO2A CSNK2B CUL3 FAM175A FOS HDAC4 HDAC9 HIF1A HIPK2 HNF4A HOMEZ HSF2 JUN KALRN KDM1A KRT14 KRT5 KRT8 LEF1 MAF1 MAST2 MDC1 MSX1 MYB NFKBIA PARP1 PIAS1 PIAS2 PIAS3 PIAS4 PML RAC1 RANGAP1 RB1 RNF111 RNF4 SAE1 SENP1 SENP2 SENP3 SENP5 SENP6 SENP7 SETDB1 SETX SH3KBP1 SLC22A2 SNCA SOX10 SOX6 SP100 STK24 SUMO1 TDG TDP2 TEAD3 TNIP1 TOPORS TP53BP2 TRIM63 UBA2 UBE2I USP25 USPL1 VIM WRN XPC ZBTB1 ZCCHC12 ZCCHC7 ZHX1 ZMYM2 ZMYM5
Entrez ID		54918	6613
HPRD ID		06987	04332
Ensembl ID		ENSG00000091317	ENSG00000188612
Uniprot IDs		Q9NX76	P61956
PDB IDs			1WM2 1WM3 1WZ0 1Z5Q 2AWT 2CKH 2D07 2IO0 2IO3 2IYD 2RPQ 3UIN 3UIO
Enriched GO Terms of Interacting Partners?		Regulation Of Neurogenesis Response To Ionizing Radiation Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Cellular Hyperosmotic Salinity Response S-adenosylmethioninamine Metabolic Process Regulation Of Cell Development DNA Methylation On Cytosine Within A CG Sequence Cellular Response To Manganese Ion Cellular Response To X-ray C-5 Methylation Of Cytosine Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation S-adenosylhomocysteine Metabolic Process Regulation Of Brown Fat Cell Differentiation Methylation-dependent Chromatin Silencing Establishment Of Integrated Proviral Latency Cellular Hyperosmotic Response Hyperosmotic Salinity Response Establishment Of Viral Latency Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Regulation Of Respiratory Burst Cellular Response To Salt Stress Negative Regulation Of Histone H3-K9 Methylation DNA Methylation On Cytosine Negative Regulation Of JUN Kinase Activity DNA Ligation Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Neurogenesis Leukocyte Migration Involved In Inflammatory Response Response To Manganese Ion Protein Complex Localization Negative Regulation Of Histone Methylation Generation Of Neurons Regulation Of Cell Differentiation Response To Radiation Negative Regulation Of Oligodendrocyte Differentiation Double-strand Break Repair Via Nonhomologous End Joining Neurogenesis Regulation Of Histone H3-K4 Methylation Hyperosmotic Response Response To Bacterium Protein Sumoylation Positive Regulation Of Cell Development Regulation Of Gene Expression By Genetic Imprinting Hexose Transmembrane Transport V(D)J Recombination Cellular Response To Osmotic Stress Cellular Response To Stimulus Response To X-ray Negative Regulation Of JNK Cascade	Protein Sumoylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Peptidyl-lysine Modification Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Binding RNA Metabolic Process Cellular Metabolic Process Gene Expression Chromosome Organization Organelle Organization Regulation Of DNA Binding Biosynthetic Process Response To Stimulus Regulation Of Cellular Process Cellular Response To Stimulus Negative Regulation Of Binding Protein Modification By Small Protein Conjugation Peptidyl-amino Acid Modification Regulation Of Cell Differentiation Regulation Of Signal Transduction Cellular Response To Stress
Tagcloud ?			augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief rev1 sensing short specialized starvation suppressor therapies toxic turn
Tagcloud (Difference) ?			augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief rev1 sensing short specialized starvation suppressor therapies toxic turn
Tagcloud (Intersection) ?