CMTM6 and CD160

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CMTM6	CD160
Description		CKLF like MARVEL transmembrane domain containing 6	CD160 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Membrane Early Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Recycling Endosome Membrane	Extracellular Region Plasma Membrane Membrane Side Of Membrane
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Signaling Receptor Binding Protein Binding Kinase Binding MHC Class I Protein Complex Binding MHC Class I Receptor Activity MHC Class Ib Receptor Activity Activating MHC Class I Receptor Activity
	Biological Process	Protein Transport Regulation Of Protein Stability Endocytic Recycling	Angiogenesis Positive Regulation Of Cytokine Production Adaptive Immune Response Immune System Process Mucosal Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Natural Killer Cell Cytokine Production Regulation Of Adaptive Immune Response Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Negative Regulation Of Angiogenesis T Cell Costimulation Positive Regulation Of Type II Interferon Production Positive Regulation Of Natural Killer Cell Degranulation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Gram-negative Bacterium Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation Negative Regulation Of Adaptive Immune Memory Response Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways		Neutrophil degranulation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) Cholesterol, total ( 24097068) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 28334899 32203549) Low density lipoprotein cholesterol levels ( 32154731) Total cholesterol levels ( 28334899 30275531)	Diastolic blood pressure ( 30224653)
Interacting Genes		23 interacting genes: APOA5 ATP13A2 BPIFA2 CD160 CD40 CIAO2A COQ8A DNMT3B DUSP10 ECPAS EHHADH FAM9B MIEF1 PPBP RBFA RBMX RUSC1 SNRPB2 SPG21 SUMO2 TCEA2 TMED8 XRCC6	8 interacting genes: AGTRAP CMTM5 CMTM6 MAL2 MDM4 SYP THRA TNFRSF14
Entrez ID		54918	11126
HPRD ID		06987	06833
Ensembl ID		ENSG00000091317	ENSG00000117281
Uniprot IDs		Q9NX76	O95971 Q6FH89
PDB IDs			6NG3 6NG9 6NGG 7MSG
Enriched GO Terms of Interacting Partners?
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