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CMTM6 and PPBP
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
CMTM6
PPBP
Gene Name
CKLF-like MARVEL transmembrane domain containing 6
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Membrane
Integral Component Of Membrane
Extracellular Vesicular Exosome
Extracellular Region
Extracellular Space
Platelet Alpha Granule Lumen
Molecular Function
Cytokine Activity
Glucose Transmembrane Transporter Activity
Chemokine Activity
Growth Factor Activity
CXCR Chemokine Receptor Binding
Biological Process
Chemotaxis
Leukocyte Migration Involved In Inflammatory Response
Platelet Degranulation
Positive Regulation Of Leukocyte Chemotaxis
Inflammatory Response
Immune Response
G-protein Coupled Receptor Signaling Pathway
Blood Coagulation
Glucose Transport
Platelet Activation
Response To Lipopolysaccharide
Regulation Of Cell Proliferation
Defense Response To Bacterium
Positive Regulation Of Cell Division
Cell Chemotaxis
Chemokine-mediated Signaling Pathway
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Class A/1 (Rhodopsin-like receptors)
Platelet degranulation
GPCR ligand binding
Metabolic disorders of biological oxidation enzymes
GPCR downstream signaling
Peptide ligand-binding receptors
Chemokine receptors bind chemokines
Response to elevated platelet cytosolic Ca2+
G alpha (i) signalling events
Platelet activation, signaling and aggregation
Drugs
Ethanesulfonic Acid
Diseases
GWAS
Metabolite levels (
22916037
)
Protein-Protein Interactions
7 interactors:
ATP13A2
DNMT3B
DUSP10
FAM9B
PPBP
SUMO2
XRCC6
21 interactors:
CELF1
CMTM6
COPG1
COPS7A
COX17
CSNK2A1
CTSG
CXCR1
CXCR2
DMWD
EFNA1
MAPK6
MOB3B
NDUFB11
NR4A1
PLEKHJ1
PMAIP1
RAB10
RPS27
SCFD1
STRN4
Entrez ID
54918
5473
HPRD ID
06987
07171
Ensembl ID
ENSG00000091317
Uniprot IDs
Q9NX76
P02775
PDB IDs
1F9P
1NAP
1TVX
Enriched GO Terms of Interacting Partners
?
Regulation Of Neurogenesis
Response To Ionizing Radiation
Negative Regulation Of Respiratory Burst Involved In Inflammatory Response
Cellular Hyperosmotic Salinity Response
S-adenosylmethioninamine Metabolic Process
Regulation Of Cell Development
DNA Methylation On Cytosine Within A CG Sequence
Cellular Response To Manganese Ion
Cellular Response To X-ray
C-5 Methylation Of Cytosine
Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation
S-adenosylhomocysteine Metabolic Process
Regulation Of Brown Fat Cell Differentiation
Methylation-dependent Chromatin Silencing
Establishment Of Integrated Proviral Latency
Cellular Hyperosmotic Response
Hyperosmotic Salinity Response
Establishment Of Viral Latency
Response To Lipopolysaccharide
Response To Molecule Of Bacterial Origin
Regulation Of Respiratory Burst
Cellular Response To Salt Stress
Negative Regulation Of Histone H3-K9 Methylation
DNA Methylation On Cytosine
Negative Regulation Of JUN Kinase Activity
DNA Ligation
Positive Regulation Of Histone H3-K4 Methylation
Positive Regulation Of Neurogenesis
Leukocyte Migration Involved In Inflammatory Response
Response To Manganese Ion
Protein Complex Localization
Negative Regulation Of Histone Methylation
Generation Of Neurons
Regulation Of Cell Differentiation
Response To Radiation
Negative Regulation Of Oligodendrocyte Differentiation
Double-strand Break Repair Via Nonhomologous End Joining
Neurogenesis
Regulation Of Histone H3-K4 Methylation
Hyperosmotic Response
Response To Bacterium
Protein Sumoylation
Positive Regulation Of Cell Development
Regulation Of Gene Expression By Genetic Imprinting
Hexose Transmembrane Transport
V(D)J Recombination
Cellular Response To Osmotic Stress
Cellular Response To Stimulus
Response To X-ray
Negative Regulation Of JNK Cascade
Interleukin-8-mediated Signaling Pathway
Chemotaxis
Response To External Stimulus
Dendritic Cell Chemotaxis
Dendritic Cell Migration
Locomotion
Cell Chemotaxis
Retrograde Vesicle-mediated Transport, Golgi To ER
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Receptor Internalization
Movement Of Cell Or Subcellular Component
Vesicle Docking Involved In Exocytosis
Negative Regulation Of Neutrophil Apoptotic Process
Basolateral Protein Localization
Chemokine-mediated Signaling Pathway
Golgi Vesicle Transport
Vesicle Docking
Neutrophil Mediated Killing Of Gram-positive Bacterium
Receptor Metabolic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity
Membrane Docking
Post-Golgi Vesicle-mediated Transport
Negative Regulation Of Dendritic Spine Morphogenesis
Negative Regulation Of Autophagic Vacuole Assembly
Establishment Of Neuroblast Polarity
Establishment Of Protein Localization To Endoplasmic Reticulum Membrane
Defense Response
Leukocyte Chemotaxis
Establishment Of Protein Localization To Endoplasmic Reticulum
Regulation Of Endopeptidase Activity
Cell Migration
Endocardial Cushion To Mesenchymal Transition Involved In Heart Valve Formation
Membrane Organization
Regulation Of Peptidase Activity
Vesicle-mediated Transport
Immune System Process
Negative Regulation Of Mitochondrial Membrane Potential
Aortic Valve Morphogenesis
Endocardial Cushion To Mesenchymal Transition
Notochord Formation
Cell Motility
Regulation Of Protein Metabolic Process
Protein Localization To Endoplasmic Reticulum
Intracellular Transport
Acute Inflammatory Response To Antigenic Stimulus
Negative Regulation Of Dendritic Spine Development
Mitral Valve Morphogenesis
Mitral Valve Development
Tagcloud
?
10q
4q
another
chemokine
constitutes
cr
cxc
divergent
evolutionary
gcp2
genbridge
gro1
gro2
gro3
il8
inp10
mapped
mentioned
mig
pair
panel
pf4
pf4v1
phylogenetic
physically
primers
scyb5
sdf1
separated
Tagcloud (Difference)
?
10q
4q
another
chemokine
constitutes
cr
cxc
divergent
evolutionary
gcp2
genbridge
gro1
gro2
gro3
il8
inp10
mapped
mentioned
mig
pair
panel
pf4
pf4v1
phylogenetic
physically
primers
scyb5
sdf1
separated
Tagcloud (Intersection)
?