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CMTM6 and DNMT3B
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
CMTM6
DNMT3B
Gene Name
CKLF-like MARVEL transmembrane domain containing 6
DNA (cytosine-5-)-methyltransferase 3 beta
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Membrane
Integral Component Of Membrane
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Nuclear Heterochromatin
Cytoplasm
Intracellular Membrane-bounded Organelle
Molecular Function
Cytokine Activity
Transcription Corepressor Activity
DNA (cytosine-5-)-methyltransferase Activity
Protein Binding
DNA-methyltransferase Activity
Unmethylated CpG Binding
Metal Ion Binding
DNA (cytosine-5-)-methyltransferase Activity, Acting On CpG Substrates
Biological Process
Chemotaxis
Negative Regulation Of Transcription From RNA Polymerase II Promoter
DNA Methylation
Methylation-dependent Chromatin Silencing
Regulation Of Gene Expression By Genetic Imprinting
Response To Ionizing Radiation
DNA Methylation On Cytosine Within A CG Sequence
Gene Expression
Positive Regulation Of Gene Expression
Protein Complex Localization
DNA Methylation On Cytosine
Regulation Of Gene Expression, Epigenetic
Response To Drug
Positive Regulation Of Neuron Differentiation
Negative Regulation Of Gene Expression, Epigenetic
S-adenosylhomocysteine Metabolic Process
S-adenosylmethioninamine Metabolic Process
Positive Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Histone H3-K9 Methylation
Cellular Response To Amino Acid Stimulus
C-5 Methylation Of Cytosine
Pathways
NoRC negatively regulates rRNA expression
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
PRC2 methylates histones and DNA
DNA methylation
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
7 interactors:
ATP13A2
DNMT3B
DUSP10
FAM9B
PPBP
SUMO2
XRCC6
35 interactors:
BAZ2A
CBX1
CBX3
CBX5
CMTM6
DNMT1
DNMT3A
DNMT3L
DUSP23
EED
EZH2
HDAC1
HDAC2
HELLS
KIF4A
MAP1LC3B
MBD4
NCAPG
NEDD8
NRIP1
PAM16
PCYT2
PLEKHJ1
RPS10
SMARCA5
SMC2
SPI1
SUMO1
SUV39H1
TDG
TSC22D1
UBE2I
UBE2W
WARS
ZBTB18
Entrez ID
54918
1789
HPRD ID
06987
04209
Ensembl ID
ENSG00000091317
ENSG00000088305
Uniprot IDs
Q9NX76
Q9UBC3
PDB IDs
3FLG
3QKJ
Enriched GO Terms of Interacting Partners
?
Regulation Of Neurogenesis
Response To Ionizing Radiation
Negative Regulation Of Respiratory Burst Involved In Inflammatory Response
Cellular Hyperosmotic Salinity Response
S-adenosylmethioninamine Metabolic Process
Regulation Of Cell Development
DNA Methylation On Cytosine Within A CG Sequence
Cellular Response To Manganese Ion
Cellular Response To X-ray
C-5 Methylation Of Cytosine
Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation
S-adenosylhomocysteine Metabolic Process
Regulation Of Brown Fat Cell Differentiation
Methylation-dependent Chromatin Silencing
Establishment Of Integrated Proviral Latency
Cellular Hyperosmotic Response
Hyperosmotic Salinity Response
Establishment Of Viral Latency
Response To Lipopolysaccharide
Response To Molecule Of Bacterial Origin
Regulation Of Respiratory Burst
Cellular Response To Salt Stress
Negative Regulation Of Histone H3-K9 Methylation
DNA Methylation On Cytosine
Negative Regulation Of JUN Kinase Activity
DNA Ligation
Positive Regulation Of Histone H3-K4 Methylation
Positive Regulation Of Neurogenesis
Leukocyte Migration Involved In Inflammatory Response
Response To Manganese Ion
Protein Complex Localization
Negative Regulation Of Histone Methylation
Generation Of Neurons
Regulation Of Cell Differentiation
Response To Radiation
Negative Regulation Of Oligodendrocyte Differentiation
Double-strand Break Repair Via Nonhomologous End Joining
Neurogenesis
Regulation Of Histone H3-K4 Methylation
Hyperosmotic Response
Response To Bacterium
Protein Sumoylation
Positive Regulation Of Cell Development
Regulation Of Gene Expression By Genetic Imprinting
Hexose Transmembrane Transport
V(D)J Recombination
Cellular Response To Osmotic Stress
Cellular Response To Stimulus
Response To X-ray
Negative Regulation Of JNK Cascade
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
DNA Modification
Chromatin Modification
Chromosome Organization
Chromatin Silencing
Chromatin Organization
Gene Silencing
Nucleobase-containing Compound Metabolic Process
DNA Methylation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Organelle Organization
Cellular Nitrogen Compound Metabolic Process
DNA Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Nitrogen Compound Metabolic Process
Gene Expression
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Cellular Metabolic Process
Methylation
Transcription, DNA-templated
Histone H3-K9 Modification
Chromatin Remodeling
RNA Metabolic Process
DNA Methylation On Cytosine
Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Silencing At RDNA
Histone Modification
Peptidyl-lysine Modification
Histone H4 Deacetylation
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Rhythmic Process
DNA Packaging
Regulation Of Gene Expression By Genetic Imprinting
Hypermethylation Of CpG Island
C-5 Methylation Of Cytosine
Tagcloud
?
cpg
cues
de
dense
dnmt1
dnmts
enhancers
ensure
ensures
establishment
excluded
guide
lethal
localize
methylated
methylation
methylome
methyltransferase
methyltransferases
novo
nucleosomes
observe
preferential
promoters
pwwp
reflects
setd2
transcribed
Tagcloud (Difference)
?
cpg
cues
de
dense
dnmt1
dnmts
enhancers
ensure
ensures
establishment
excluded
guide
lethal
localize
methylated
methylation
methylome
methyltransferase
methyltransferases
novo
nucleosomes
observe
preferential
promoters
pwwp
reflects
setd2
transcribed
Tagcloud (Intersection)
?