CMTM6 and COQ8A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CMTM6	COQ8A
Description		CKLF like MARVEL transmembrane domain containing 6	coenzyme Q8A
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Membrane Early Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Recycling Endosome Membrane	Mitochondrion Membrane Extrinsic Component Of Mitochondrial Inner Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Nucleotide Binding Protein Kinase Activity Protein Binding ATP Binding Enzyme Activator Activity Kinase Activity Transferase Activity ADP Binding
	Biological Process	Protein Transport Regulation Of Protein Stability Endocytic Recycling	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation
Pathways		Neutrophil degranulation	Ubiquinol biosynthesis
Drugs			Fostamatinib
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3) Coenzyme Q10 deficiency
GWAS		Apolipoprotein B levels ( 32203549) Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) Cholesterol, total ( 24097068) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 28334899 32203549) Low density lipoprotein cholesterol levels ( 32154731) Total cholesterol levels ( 28334899 30275531)
Interacting Genes		23 interacting genes: APOA5 ATP13A2 BPIFA2 CD160 CD40 CIAO2A COQ8A DNMT3B DUSP10 ECPAS EHHADH FAM9B MIEF1 PPBP RBFA RBMX RUSC1 SNRPB2 SPG21 SUMO2 TCEA2 TMED8 XRCC6	27 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 LDAF1 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM239 TPD52L2 UBC
Entrez ID		54918	56997
HPRD ID		06987	07375
Ensembl ID		ENSG00000091317	ENSG00000163050
Uniprot IDs		Q9NX76	Q8NI60
PDB IDs			4PED 5I35 7UDP 7UDQ
Enriched GO Terms of Interacting Partners?
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