CMTM6 and DUSP10

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CMTM6	DUSP10
Gene Name		CKLF-like MARVEL transmembrane domain containing 6	dual specificity phosphatase 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus
	Molecular Function	Cytokine Activity	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Phosphatase Activity
	Biological Process	Chemotaxis	Inactivation Of MAPK Activity Regulation Of Adaptive Immune Response Protein Dephosphorylation Response To Stress JNK Cascade Response To Lipopolysaccharide Peptidyl-tyrosine Dephosphorylation Negative Regulation Of JUN Kinase Activity Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Negative Regulation Of JNK Cascade Oligodendrocyte Differentiation Negative Regulation Of Oligodendrocyte Differentiation Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Regulation Of Brown Fat Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Colorectal cancer ( 20972440)
Protein-Protein Interactions		7 interactors: ATP13A2 DNMT3B DUSP10 FAM9B PPBP SUMO2 XRCC6	12 interactors: CMTM6 FHL2 FN1 HTT MAPK10 MAPK11 MAPK14 MAPK3 MAPK8 RPS11 SLX1B SNX2
Entrez ID		54918	11221
HPRD ID		06987	12320
Ensembl ID		ENSG00000091317	ENSG00000143507
Uniprot IDs		Q9NX76	B4DDQ0 Q9Y6W6
PDB IDs			1ZZW 2OUC 2OUD 3TG1
Enriched GO Terms of Interacting Partners?		Regulation Of Neurogenesis Response To Ionizing Radiation Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Cellular Hyperosmotic Salinity Response S-adenosylmethioninamine Metabolic Process Regulation Of Cell Development DNA Methylation On Cytosine Within A CG Sequence Cellular Response To Manganese Ion Cellular Response To X-ray C-5 Methylation Of Cytosine Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation S-adenosylhomocysteine Metabolic Process Regulation Of Brown Fat Cell Differentiation Methylation-dependent Chromatin Silencing Establishment Of Integrated Proviral Latency Cellular Hyperosmotic Response Hyperosmotic Salinity Response Establishment Of Viral Latency Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Regulation Of Respiratory Burst Cellular Response To Salt Stress Negative Regulation Of Histone H3-K9 Methylation DNA Methylation On Cytosine Negative Regulation Of JUN Kinase Activity DNA Ligation Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Neurogenesis Leukocyte Migration Involved In Inflammatory Response Response To Manganese Ion Protein Complex Localization Negative Regulation Of Histone Methylation Generation Of Neurons Regulation Of Cell Differentiation Response To Radiation Negative Regulation Of Oligodendrocyte Differentiation Double-strand Break Repair Via Nonhomologous End Joining Neurogenesis Regulation Of Histone H3-K4 Methylation Hyperosmotic Response Response To Bacterium Protein Sumoylation Positive Regulation Of Cell Development Regulation Of Gene Expression By Genetic Imprinting Hexose Transmembrane Transport V(D)J Recombination Cellular Response To Osmotic Stress Cellular Response To Stimulus Response To X-ray Negative Regulation Of JNK Cascade	Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response MAPK Cascade Regulation Of Innate Immune Response Signal Transduction By Phosphorylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Activation Of MAPK Activity Immune Response-regulating Signaling Pathway JUN Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Neurotrophin Signaling Pathway Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Immune Response Regulation Of MAP Kinase Activity Positive Regulation Of Signal Transduction Vascular Endothelial Growth Factor Receptor Signaling Pathway Defense Response Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Immune Response Cellular Response To Lipid Cellular Response To Stress Positive Regulation Of Catalytic Activity Positive Regulation Of Immune System Process Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Positive Regulation Of MAPK Cascade Cellular Response To Lipopolysaccharide Response To Radiation Response To Stress Cellular Response To Molecule Of Bacterial Origin Positive Regulation Of Protein Kinase Activity
Tagcloud ?			bc bcs dephosphorylate differentially distant dmfs dusp4 dusp6 enpp1 erbb2 erk ihc inpp4b microarray microarrays motility multiphosphatase phosphatases phosphatome phospho ppapdc1a relevance seemed series sharing signature subgroups unlike warranted
Tagcloud (Difference) ?			bc bcs dephosphorylate differentially distant dmfs dusp4 dusp6 enpp1 erbb2 erk ihc inpp4b microarray microarrays motility multiphosphatase phosphatases phosphatome phospho ppapdc1a relevance seemed series sharing signature subgroups unlike warranted
Tagcloud (Intersection) ?