LAX1 and NDN

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		LAX1	NDN
Gene Name		lymphocyte transmembrane adaptor 1	necdin, melanoma antigen (MAGE) family member
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane Membrane Raft	Nucleus Centrosome Cytosol Cell Projection Perikaryon
	Molecular Function	Protein Binding Protein Kinase Binding SH2 Domain Binding	DNA Binding Gamma-tubulin Binding
	Biological Process	Inactivation Of MAPK Activity Immune Response Intracellular Signal Transduction B Cell Activation Immunoglobulin Secretion Antigen Receptor-mediated Signaling Pathway Negative Regulation Of T Cell Activation	Neuron Migration Respiratory System Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nervous System Development Axonal Fasciculation Central Nervous System Development Negative Regulation Of Cell Proliferation Glial Cell Migration Post-embryonic Development Sensory Perception Of Pain Regulation Of Growth Neurotrophin TRK Receptor Signaling Pathway Axon Extension Multicellular Organismal Homeostasis Genetic Imprinting
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: GRAP2 GRB2 GRB7 LCK NDN STAMBPL1 SYK ZAP70	43 interactors: APBB1IP ARSE BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 LAX1 LPXN MIER2 MKRN2 MPP6 N6AMT2 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PJA1 PPFIA1 SERTAD3 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B
Entrez ID		54900	4692
HPRD ID		08312	03667
Ensembl ID		ENSG00000122188	ENSG00000182636
Uniprot IDs		Q8IWV1	Q99608
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Leukocyte Migration Positive Regulation Of Cell-cell Adhesion Immune Response-activating Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Cell Migration Regulation Of Lymphocyte Activation Antigen Receptor-mediated Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Beta Selection Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Peptidyl-tyrosine Autophosphorylation Fc-epsilon Receptor Signaling Pathway Locomotion Positive Regulation Of Signal Transduction Regulation Of Cell Adhesion Positive Regulation Of Immune Response Fc Receptor Signaling Pathway Movement Of Cell Or Subcellular Component T Cell Costimulation Innate Immune Response Positive Regulation Of T Cell Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Regulation Of Immune Response Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of Immune System Process Positive Regulation Of Gamma-delta T Cell Activation Cell Surface Receptor Signaling Pathway T Cell Receptor Signaling Pathway Blood Coagulation Hemostasis Regulation Of Gamma-delta T Cell Differentiation Regulation Of T Cell Differentiation Positive Regulation Of Alpha-beta T Cell Proliferation Immune System Process Regulation Of Lymphocyte Differentiation T Cell Differentiation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Body Fluid Levels Immune Response Regulation Of Immune System Process	Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Anterograde Axon Cargo Transport Regulation Of Fibroblast Proliferation Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels RNA Metabolic Process Cellular Response To Oxygen Levels Axon Transport Of Mitochondrion Wound Healing Involved In Inflammatory Response Gene Expression Response To Wounding Regulation Of Gene Expression Transcription, DNA-templated Microtubule-based Movement RNA Biosynthetic Process Cellular Localization Positive Regulation Of Fibroblast Proliferation Circadian Rhythm MRNA Transcription From RNA Polymerase II Promoter Cell Differentiation Wound Healing Regulation Of Thymocyte Apoptotic Process MRNA Transcription Transcription From RNA Polymerase II Promoter Developmental Process Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Anterograde Synaptic Vesicle Transport Regulation Of Establishment Of Protein Localization Establishment Of Localization In Cell Positive Regulation Of Natural Killer Cell Activation Melanosome Organization Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Pigment Granule Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transport Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Embryonic Placenta Development Regulation Of Cellular Localization Tissue Remodeling Iron Ion Homeostasis MRNA Stabilization Cell Morphogenesis Microtubule-based Process Anatomical Structure Development
Tagcloud ?			biallelically cancerous cdkn1c coordinately deregulated deregulating deregulation dmr dmrs exclusive h19 hoxc6 hyper hypo igf2 ign imprinted imprinting lit1 meg3 plagl1 ppp1r9a presumptive prostatic pyrosequencing qrt silico wondered zac1
Tagcloud (Difference) ?			biallelically cancerous cdkn1c coordinately deregulated deregulating deregulation dmr dmrs exclusive h19 hoxc6 hyper hypo igf2 ign imprinted imprinting lit1 meg3 plagl1 ppp1r9a presumptive prostatic pyrosequencing qrt silico wondered zac1
Tagcloud (Intersection) ?