NDN and APBB1IP

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		NDN	APBB1IP
Gene Name		necdin, melanoma antigen (MAGE) family member	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centrosome Cytosol Cell Projection Perikaryon	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium
	Molecular Function	DNA Binding Gamma-tubulin Binding	Protein Binding
	Biological Process	Neuron Migration Respiratory System Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nervous System Development Axonal Fasciculation Central Nervous System Development Negative Regulation Of Cell Proliferation Glial Cell Migration Post-embryonic Development Sensory Perception Of Pain Regulation Of Growth Neurotrophin TRK Receptor Signaling Pathway Axon Extension Multicellular Organismal Homeostasis Genetic Imprinting	Signal Transduction Blood Coagulation Platelet Activation
Pathways			p130Cas linkage to MAPK signaling for integrins Integrin alphaIIb beta3 signaling GRB2:SOS provides linkage to MAPK signaling for Integrins Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation)
Drugs
Diseases
GWAS			Inflammatory biomarkers ( 22228203) Response to angiotensin II receptor blocker therapy ( 22566498)
Protein-Protein Interactions		43 interactors: APBB1IP ARSE BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 LAX1 LPXN MIER2 MKRN2 MPP6 N6AMT2 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PJA1 PPFIA1 SERTAD3 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B	8 interactors: EVL GAS7 NDN PFN1 PRPF40A RAP1A VASP ZDHHC17
Entrez ID		4692	54518
HPRD ID		03667	16420
Ensembl ID		ENSG00000182636	ENSG00000077420
Uniprot IDs		Q99608	B4E100 Q7Z5R6
PDB IDs			3ZDL
Enriched GO Terms of Interacting Partners?		Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Anterograde Axon Cargo Transport Regulation Of Fibroblast Proliferation Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels RNA Metabolic Process Cellular Response To Oxygen Levels Axon Transport Of Mitochondrion Wound Healing Involved In Inflammatory Response Gene Expression Response To Wounding Regulation Of Gene Expression Transcription, DNA-templated Microtubule-based Movement RNA Biosynthetic Process Cellular Localization Positive Regulation Of Fibroblast Proliferation Circadian Rhythm MRNA Transcription From RNA Polymerase II Promoter Cell Differentiation Wound Healing Regulation Of Thymocyte Apoptotic Process MRNA Transcription Transcription From RNA Polymerase II Promoter Developmental Process Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Anterograde Synaptic Vesicle Transport Regulation Of Establishment Of Protein Localization Establishment Of Localization In Cell Positive Regulation Of Natural Killer Cell Activation Melanosome Organization Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Pigment Granule Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transport Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Embryonic Placenta Development Regulation Of Cellular Localization Tissue Remodeling Iron Ion Homeostasis MRNA Stabilization Cell Morphogenesis Microtubule-based Process Anatomical Structure Development	Actin Polymerization Or Depolymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Regulation Of Cellular Component Organization Cytoskeleton Organization Regulation Of Ruffle Assembly Nervous System Development Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Actin Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Cytoskeleton Organization Neuron Projection Morphogenesis Actin Filament-based Process Generation Of Neurons Neurogenesis Neuron Projection Development Cell Projection Morphogenesis Positive Regulation Of Stress Fiber Assembly Actin Filament Organization Cell Part Morphogenesis Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Cellular Component Biogenesis Cell Development Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Neuron Development Regulation Of Actin Cytoskeleton Organization Regulation Of Stress Fiber Assembly Protein Homotetramerization Cell Morphogenesis Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Neuron Differentiation Cell Projection Organization Regulation Of Cell Projection Organization Locomotion Anatomical Structure Morphogenesis Regulation Of Cytoskeleton Organization Protein Tetramerization Neural Tube Closure Axonogenesis System Development Regulation Of Cell Projection Assembly Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Neural Tube Formation Response To Growth Factor
Tagcloud ?		biallelically cancerous cdkn1c coordinately deregulated deregulating deregulation dmr dmrs exclusive h19 hoxc6 hyper hypo igf2 ign imprinted imprinting lit1 meg3 plagl1 ppp1r9a presumptive prostatic pyrosequencing qrt silico wondered zac1
Tagcloud (Difference) ?		biallelically cancerous cdkn1c coordinately deregulated deregulating deregulation dmr dmrs exclusive h19 hoxc6 hyper hypo igf2 ign imprinted imprinting lit1 meg3 plagl1 ppp1r9a presumptive prostatic pyrosequencing qrt silico wondered zac1
Tagcloud (Intersection) ?