LAX1 and STAMBPL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LAX1	STAMBPL1
Gene Name		lymphocyte transmembrane adaptor 1	STAM binding protein-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane Membrane Raft	Membrane
	Molecular Function	Protein Binding Protein Kinase Binding SH2 Domain Binding	Protein Binding Metallopeptidase Activity Metal Ion Binding
	Biological Process	Inactivation Of MAPK Activity Immune Response Intracellular Signal Transduction B Cell Activation Immunoglobulin Secretion Antigen Receptor-mediated Signaling Pathway Negative Regulation Of T Cell Activation	Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: GRAP2 GRB2 GRB7 LCK NDN STAMBPL1 SYK ZAP70	21 interactors: A2M CDC37 CEP72 ECSIT GNPTAB GOLGA2 IKZF3 INCA1 LAX1 MAGEA6 MAST1 PNMA1 PSEN1 RAB2A RNF11 RNF32 SMAD2 SMAD7 TCF4 TRIM27 TRIP13
Entrez ID		54900	57559
HPRD ID		08312	16486
Ensembl ID		ENSG00000122188	ENSG00000138134
Uniprot IDs		Q8IWV1	Q96FJ0
PDB IDs			2ZNR 2ZNV
Enriched GO Terms of Interacting Partners?		Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Leukocyte Migration Positive Regulation Of Cell-cell Adhesion Immune Response-activating Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Cell Migration Regulation Of Lymphocyte Activation Antigen Receptor-mediated Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Beta Selection Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Peptidyl-tyrosine Autophosphorylation Fc-epsilon Receptor Signaling Pathway Locomotion Positive Regulation Of Signal Transduction Regulation Of Cell Adhesion Positive Regulation Of Immune Response Fc Receptor Signaling Pathway Movement Of Cell Or Subcellular Component T Cell Costimulation Innate Immune Response Positive Regulation Of T Cell Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Regulation Of Immune Response Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of Immune System Process Positive Regulation Of Gamma-delta T Cell Activation Cell Surface Receptor Signaling Pathway T Cell Receptor Signaling Pathway Blood Coagulation Hemostasis Regulation Of Gamma-delta T Cell Differentiation Regulation Of T Cell Differentiation Positive Regulation Of Alpha-beta T Cell Proliferation Immune System Process Regulation Of Lymphocyte Differentiation T Cell Differentiation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Body Fluid Levels Immune Response Regulation Of Immune System Process	Cellular Localization Protein Localization Establishment Of Localization In Cell Secretion By Cell Protein Secretion Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Protein Transport Secretion Regulation Of Epithelial To Mesenchymal Transition Establishment Of Protein Localization Negative Regulation Of Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of BMP Signaling Pathway Regulation Of Binding Negative Regulation Of Protein Metabolic Process Cellular Protein Complex Localization Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Complex Localization Negative Regulation Of Cellular Metabolic Process Regulation Of Activin Receptor Signaling Pathway Regulation Of Protein Phosphorylation Post-embryonic Development Mesoderm Development Regulation Of Protein Metabolic Process Regulation Of Protein Binding Regulation Of Protein Kinase Activity Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Kinase Activity Regulation Of Catalytic Activity Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Immune System Process Intracellular Signal Transduction Regulation Of Phosphorylation Regulation Of Cell Morphogenesis Cellular Component Assembly Regulation Of Immune Response Cell Cycle Cellular Protein Localization Negative Regulation Of BMP Signaling Pathway Regulation Of Cellular Protein Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Stem Cell Differentiation
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