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NDN and EEF1AKMT1
Number of citations of the paper that reports this interaction (PubMedID
24722188
)
69
Data Source:
BioGRID
(two hybrid, two hybrid)
NDN
EEF1AKMT1
Description
necdin, MAGE family member
EEF1A lysine methyltransferase 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Protein-containing Complex
Cell Projection
Perikaryon
Cytoplasm
Cytosol
Molecular Function
DNA Binding
Protein Binding
Gamma-tubulin Binding
Promoter-specific Chromatin Binding
Nucleic Acid Binding
Methyltransferase Activity
Protein-lysine N-methyltransferase Activity
Transferase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Neuron Migration
Respiratory System Process
Regulation Of DNA-templated Transcription
Axonogenesis
Axonal Fasciculation
Central Nervous System Development
Respiratory Gaseous Exchange By Respiratory System
Glial Cell Migration
Post-embryonic Development
Sensory Perception Of Pain
Neuron Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Neurotrophin TRK Receptor Signaling Pathway
Neuron Development
Axon Extension
Multicellular Organismal-level Homeostasis
Genomic Imprinting
Peptidyl-lysine Methylation
Methylation
Pathways
Interleukin-4 and Interleukin-13 signaling
Protein methylation
Drugs
Diseases
Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS
Body size at age 10 (
32376654
)
Depressive symptoms (SSRI exposure interaction) (
25649181
)
HDL cholesterol levels (
32203549
)
Parkinson's disease (age of onset) (
33884653
)
Plasma anti-thyroid peroxidase levels (
29678681
)
Serum metabolite concentrations in chronic kidney disease (
29545352
)
Interacting Genes
47 interacting genes:
APBB1IP
ARSL
BLOC1S6
CALCOCO2
CCDC136
CDR2
DTNBP1
E2F1
E2F4
EEF1AKMT1
EGFR
EID1
EPAS1
FAM131C
FSD2
FXR2
GKAP1
GOLGA2
HIF1A
HNRNPU
IFFO1
IL1A
IL32
IRS4
LAX1
LPXN
MIER2
MKRN2
MYG1
NEFL
NGFR
NUBP1
NUCB1
NUCB2
P4HA3
PALS2
PJA1
PPARGC1A
PPFIA1
SERTAD3
SIRT1
SSX2IP
TFIP11
TP53
U2AF1
ZBTB1
ZBTB7B
1 interacting genes:
NDN
Entrez ID
4692
221143
HPRD ID
03667
14135
Ensembl ID
ENSG00000182636
ENSG00000150456
Uniprot IDs
Q99608
X5D982
B2RE94
Q8WVE0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cis-regulatory Region Sequence-specific DNA Binding
Axo-dendritic Transport
Circadian Rhythm
Transport Along Microtubule
Cellular Response To Hypoxia
Positive Regulation Of MiRNA Metabolic Process
Positive Regulation Of MiRNA Transcription
Neuron Apoptotic Process
Cytoskeleton-dependent Intracellular Transport
Axon Cytoplasm
Microtubule-based Transport
Axonal Transport
Circadian Regulation Of Gene Expression
Regulation Of Brown Fat Cell Differentiation
Positive Regulation Of Insulin Receptor Signaling Pathway
Positive Regulation Of Cellular Response To Insulin Stimulus
Cytoplasm
Cellular Response To Decreased Oxygen Levels
DNA-binding Transcription Activator Activity
Promoter-specific Chromatin Binding
Embryonic Placenta Development
Cellular Homeostasis
Regulation Of MiRNA Transcription
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Connective Tissue Replacement Involved In Inflammatory Response Wound Healing
Rhythmic Process
Cellular Response To Oxygen Levels
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of MiRNA Metabolic Process
Intracellular Chemical Homeostasis
Organelle Transport Along Microtubule
Intracellular Glucose Homeostasis
Regulation Of Fibroblast Proliferation
Positive Regulation Of Biosynthetic Process
Stress-induced Premature Senescence
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Protein-containing Complex
MRNA Metabolic Process
PML Body
Anterograde Axonal Transport
Nuclear Receptor Binding
Connective Tissue Replacement
Microtubule-based Process
Intracellular Oxygen Homeostasis
Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Positive Regulation Of Gene Expression
Protein Domain Specific Binding
Respiratory Gaseous Exchange By Respiratory System
Epigenetic Programming Of Gene Expression
Neurotrophin Signaling Pathway
Glial Cell Migration
Axonal Fasciculation
Respiratory System Process
Gamma-tubulin Binding
Neuron Projection Fasciculation
Genomic Imprinting
Neurotrophin TRK Receptor Signaling Pathway
Axon Extension
Neuron Recognition
Sensory Perception Of Pain
Post-embryonic Development
Promoter-specific Chromatin Binding
Neuron Projection Extension
Perikaryon
Cell Recognition
Developmental Cell Growth
Developmental Growth Involved In Morphogenesis
Axonogenesis
Central Nervous System Development
Neuron Migration
Neuron Development
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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