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PPP1R12C and MYL2
Number of citations of the paper that reports this interaction (PMID
11399775
)
36
Data Source:
HPRD
(in vivo, in vitro)
PPP1R12C
MYL2
Gene Name
protein phosphatase 1, regulatory subunit 12C
myosin, light chain 2, regulatory, cardiac, slow
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoskeleton
Actin Cytoskeleton
Myosin Complex
Myofibril
Sarcomere
A Band
Molecular Function
Protein Binding
Actin Monomer Binding
Calcium Ion Binding
Protein Binding
Structural Constituent Of Muscle
Myosin Heavy Chain Binding
Biological Process
Regulation Of Striated Muscle Contraction
Post-embryonic Development
Muscle Filament Sliding
Negative Regulation Of Cell Growth
Muscle Cell Fate Specification
Muscle Fiber Development
Cardiac Myofibril Assembly
Ventricular Cardiac Muscle Tissue Morphogenesis
Heart Contraction
Cardiac Muscle Contraction
Pathways
Striated Muscle Contraction
Drugs
Diseases
GWAS
Alcohol consumption (
21270382
)
Coronary heart disease (
23364394
)
Drinking behavior (
23364009
)
Gamma glutamyl transpeptidase (
21909109
)
Glycemic traits (
23575436
)
HDL cholesterol (
21909109
)
Protein-Protein Interactions
11 interactors:
ATXN7
C1orf109
CACNA1A
CDC42BPA
IL16
MPRIP
MYL2
PAFAH1B2
PPP1CB
RBM17
SMAD3
9 interactors:
CDC42BPA
GJB5
LRSAM1
MYOC
NHP2
PAK2
PPP1R12C
TRIM63
USP6
Entrez ID
54776
4633
HPRD ID
11452
01181
Ensembl ID
ENSG00000125503
ENSG00000111245
Uniprot IDs
B4DME2
Q9BZL4
P10916
Q6IB42
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Positive Chemotaxis
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Cerebellar Molecular Layer Development
Positive Regulation Of Transforming Growth Factor Beta3 Production
Muscle Cell Fate Specification
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Chemotaxis
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Vestibular Nucleus Development
Actomyosin Structure Organization
Positive Regulation Of Behavior
Regulation Of Chemotaxis
Cerebellum Maturation
Musculoskeletal Movement, Spinal Reflex Action
Evasion Or Tolerance Of Host Defenses By Virus
Energy Reserve Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Positive Regulation Of Extracellular Matrix Assembly
Gamma-aminobutyric Acid Secretion
Negative Regulation Of Cell Growth
Regulation Of Extracellular Matrix Assembly
Regulation Of Acetylcholine Secretion, Neurotransmission
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Behavior
Rhythmic Synaptic Transmission
Primary MiRNA Processing
Response To Transforming Growth Factor Beta
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Regulation Of Glycogen Catabolic Process
Negative Regulation Of Osteoblast Proliferation
SMAD Protein Complex Assembly
Heart Morphogenesis
Response To External Stimulus
Cellular Chloride Ion Homeostasis
Calcium Ion-dependent Exocytosis Of Neurotransmitter
Regulation Of Transforming Growth Factor Beta2 Production
Chloride Ion Homeostasis
Transdifferentiation
Gamma-aminobutyric Acid Transport
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Growth
Lipid Catabolic Process
Positive Regulation Of Catenin Import Into Nucleus
Negative Regulation Of Hormone Biosynthetic Process
Positive Regulation Of Alkaline Phosphatase Activity
Pons Development
Skeletal Muscle Adaptation
ERBB2-ERBB3 Signaling Pathway
Skeletal Muscle Hypertrophy
RRNA Pseudouridine Synthesis
Ubiquitin-dependent Endocytosis
ERBB2 Signaling Pathway
Protein Catabolic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Spongiotrophoblast Differentiation
Cellular Protein Modification Process
Non-canonical Wnt Signaling Pathway Via JNK Cascade
Skeletal Muscle Atrophy
Non-canonical Wnt Signaling Pathway Via MAPK Cascade
Striated Muscle Atrophy
Muscle Atrophy
Clustering Of Voltage-gated Sodium Channels
Negative Regulation Of Execution Phase Of Apoptosis
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Viral Budding
Proteasomal Protein Catabolic Process
Muscle System Process
Positive Regulation Of Mitochondrial Depolarization
Negative Regulation Of Stress Fiber Assembly
Neuronal Ion Channel Clustering
Nuclear Migration
Negative Regulation Of Actin Filament Bundle Assembly
Tagcloud
?
calcium
carrier
cav1
channel
codes
computational
evidences
gla
herein
knockdown
messenger
mgp
mrfs
mscs
muscle
myh3
myogenesis
myogenic
myosin
myotube
retinol
satellite
signifies
t4
thyroxin
transportation
transthyretin
ttr
voltage
Tagcloud (Difference)
?
calcium
carrier
cav1
channel
codes
computational
evidences
gla
herein
knockdown
messenger
mgp
mrfs
mscs
muscle
myh3
myogenesis
myogenic
myosin
myotube
retinol
satellite
signifies
t4
thyroxin
transportation
transthyretin
ttr
voltage
Tagcloud (Intersection)
?