MYL2 and NHP2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MYL2	NHP2
Gene Name		myosin, light chain 2, regulatory, cardiac, slow	NHP2 ribonucleoprotein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Actin Cytoskeleton Myosin Complex Myofibril Sarcomere A Band	Nucleoplasm Nucleolus Small Nucleolar Ribonucleoprotein Complex Cytoplasm Cajal Body
	Molecular Function	Actin Monomer Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding	SnoRNA Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Striated Muscle Contraction Post-embryonic Development Muscle Filament Sliding Negative Regulation Of Cell Growth Muscle Cell Fate Specification Muscle Fiber Development Cardiac Myofibril Assembly Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction	RRNA Pseudouridine Synthesis
Pathways		Striated Muscle Contraction	Telomere Maintenance Chromosome Maintenance Extension of Telomeres Telomere Extension By Telomerase
Drugs
Diseases
GWAS		Alcohol consumption ( 21270382) Coronary heart disease ( 23364394) Drinking behavior ( 23364009) Gamma glutamyl transpeptidase ( 21909109) Glycemic traits ( 23575436) HDL cholesterol ( 21909109)
Protein-Protein Interactions		9 interactors: CDC42BPA GJB5 LRSAM1 MYOC NHP2 PAK2 PPP1R12C TRIM63 USP6	8 interactors: IKBKG JMJD6 MYL2 NEDD4 NEDD4L NOP10 PRNP UBC
Entrez ID		4633	55651
HPRD ID		01181	07570
Ensembl ID		ENSG00000111245	ENSG00000145912
Uniprot IDs		P10916 Q6IB42	J3QSY4 Q9NX24
PDB IDs
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Adaptation ERBB2-ERBB3 Signaling Pathway Skeletal Muscle Hypertrophy RRNA Pseudouridine Synthesis Ubiquitin-dependent Endocytosis ERBB2 Signaling Pathway Protein Catabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Spongiotrophoblast Differentiation Cellular Protein Modification Process Non-canonical Wnt Signaling Pathway Via JNK Cascade Skeletal Muscle Atrophy Non-canonical Wnt Signaling Pathway Via MAPK Cascade Striated Muscle Atrophy Muscle Atrophy Clustering Of Voltage-gated Sodium Channels Negative Regulation Of Execution Phase Of Apoptosis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Viral Budding Proteasomal Protein Catabolic Process Muscle System Process Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Stress Fiber Assembly Neuronal Ion Channel Clustering Nuclear Migration Negative Regulation Of Actin Filament Bundle Assembly	Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Sodium Ion Transport Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Viral Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Cellular Response To Growth Factor Stimulus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Intracellular Receptor Signaling Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Protein Catabolic Process Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Response To Metal Ion Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Regulation Of DNA-templated Transcription In Response To Stress I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Sodium Ion Transport MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Protein Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Ion Transmembrane Transport Regulation Of Protein Metabolic Process Positive Regulation Of Type I Interferon Production Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Muscle Cell Fate Specification Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Striated Muscle Contraction JNK Cascade Response To Inorganic Substance Positive Regulation Of Protein Metabolic Process
Tagcloud ?		calcium carrier cav1 channel codes computational evidences gla herein knockdown messenger mgp mrfs mscs muscle myh3 myogenesis myogenic myosin myotube retinol satellite signifies t4 thyroxin transportation transthyretin ttr voltage	acd bi boundaries characterised congenita dc directional dkc1 dyskeratosis dystrophic ex1 ex9 exceedingly inherited intron leukoplakia nails nop10 pigmentation pot1 shelterin sixteen telomeres terc terf1 terf2 terf2ip tert tinf2
Tagcloud (Difference) ?		calcium carrier cav1 channel codes computational evidences gla herein knockdown messenger mgp mrfs mscs muscle myh3 myogenesis myogenic myosin myotube retinol satellite signifies t4 thyroxin transportation transthyretin ttr voltage	acd bi boundaries characterised congenita dc directional dkc1 dyskeratosis dystrophic ex1 ex9 exceedingly inherited intron leukoplakia nails nop10 pigmentation pot1 shelterin sixteen telomeres terc terf1 terf2 terf2ip tert tinf2
Tagcloud (Intersection) ?