MYL2

Gene Name		myosin, light chain 2, regulatory, cardiac, slow
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Actin Cytoskeleton Myosin Complex Myofibril Sarcomere A Band
	Molecular Function	Actin Monomer Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding
	Biological Process	Regulation Of Striated Muscle Contraction Post-embryonic Development Muscle Filament Sliding Negative Regulation Of Cell Growth Muscle Cell Fate Specification Muscle Fiber Development Cardiac Myofibril Assembly Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS		Alcohol consumption ( 21270382) Coronary heart disease ( 23364394) Drinking behavior ( 23364009) Gamma glutamyl transpeptidase ( 21909109) Glycemic traits ( 23575436) HDL cholesterol ( 21909109)
Protein-protein Interactions		9 interactors: CDC42BPA GJB5 LRSAM1 MYOC NHP2 PAK2 PPP1R12C TRIM63 USP6
Entrez ID		4633
HPRD ID		01181
Ensembl ID		ENSG00000111245
Uniprot IDs		P10916 Q6IB42
PDB IDs
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Adaptation ERBB2-ERBB3 Signaling Pathway Skeletal Muscle Hypertrophy RRNA Pseudouridine Synthesis Ubiquitin-dependent Endocytosis ERBB2 Signaling Pathway Protein Catabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Spongiotrophoblast Differentiation Cellular Protein Modification Process Non-canonical Wnt Signaling Pathway Via JNK Cascade Skeletal Muscle Atrophy Non-canonical Wnt Signaling Pathway Via MAPK Cascade Striated Muscle Atrophy Muscle Atrophy Clustering Of Voltage-gated Sodium Channels Negative Regulation Of Execution Phase Of Apoptosis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Viral Budding Proteasomal Protein Catabolic Process Muscle System Process Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Stress Fiber Assembly Neuronal Ion Channel Clustering Nuclear Migration Negative Regulation Of Actin Filament Bundle Assembly
Tagcloud ?		calcium carrier cav1 channel codes computational evidences gla herein knockdown messenger mgp mrfs mscs muscle myh3 myogenesis myogenic myosin myotube retinol satellite signifies t4 thyroxin transportation transthyretin ttr voltage