PPP1R12C and IL16

Number of citations of the paper that reports this interaction (PMID 12923170)
5

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		PPP1R12C	IL16
Gene Name		protein phosphatase 1, regulatory subunit 12C	interleukin 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Extracellular Space Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding	Cytokine Activity
	Biological Process		Transcription, DNA-templated Regulation Of Transcription, DNA-templated Immune Response Viral Process Leukocyte Chemotaxis Induction Of Positive Chemotaxis
Pathways
Drugs
Diseases
GWAS			Inattentive symptoms ( 18821565)
Protein-Protein Interactions		11 interactors: ATXN7 C1orf109 CACNA1A CDC42BPA IL16 MPRIP MYL2 PAFAH1B2 PPP1CB RBM17 SMAD3	28 interactors: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ1 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A PPP1R12A PPP1R12B PPP1R12C SSSCA1 SUV39H1 USHBP1
Entrez ID		54776	3603
HPRD ID		11452	04329
Ensembl ID		ENSG00000125503	ENSG00000172349
Uniprot IDs		B4DME2 Q9BZL4	Q14005 Q9UME6
PDB IDs			1I16 1X6D
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Positive Chemotaxis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cerebellar Molecular Layer Development Positive Regulation Of Transforming Growth Factor Beta3 Production Muscle Cell Fate Specification Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Chemotaxis Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Vestibular Nucleus Development Actomyosin Structure Organization Positive Regulation Of Behavior Regulation Of Chemotaxis Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Evasion Or Tolerance Of Host Defenses By Virus Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Gamma-aminobutyric Acid Secretion Negative Regulation Of Cell Growth Regulation Of Extracellular Matrix Assembly Regulation Of Acetylcholine Secretion, Neurotransmission Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Behavior Rhythmic Synaptic Transmission Primary MiRNA Processing Response To Transforming Growth Factor Beta Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Regulation Of Glycogen Catabolic Process Negative Regulation Of Osteoblast Proliferation SMAD Protein Complex Assembly Heart Morphogenesis Response To External Stimulus Cellular Chloride Ion Homeostasis Calcium Ion-dependent Exocytosis Of Neurotransmitter Regulation Of Transforming Growth Factor Beta2 Production Chloride Ion Homeostasis Transdifferentiation Gamma-aminobutyric Acid Transport Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Growth Lipid Catabolic Process Positive Regulation Of Catenin Import Into Nucleus Negative Regulation Of Hormone Biosynthetic Process Positive Regulation Of Alkaline Phosphatase Activity Pons Development	Synaptic Transmission Potassium Ion Transmembrane Transport Potassium Ion Transport Potassium Ion Import Cell-cell Signaling Cation Transmembrane Transport Signaling Cell Communication Ion Transmembrane Transport Metal Ion Transport Regulation Of Ion Transmembrane Transport Cation Transport Transmembrane Transport Ion Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Ion Transport Monovalent Inorganic Cation Transport Regulation Of Membrane Potential Regulation Of Cellular Process Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Regulation Of Sensory Perception Of Pain Startle Response Directional Locomotion Protein Homooligomerization Membrane Depolarization Negative Regulation Of Protein Catabolic Process Neuromuscular Process Regulation Of Resting Membrane Potential Regulation Of Neurological System Process Regulation Of Protein Catabolic Process Cell Cycle Regulation Of Excitatory Postsynaptic Membrane Potential Mitotic Cell Cycle Process Regulation Of Postsynaptic Membrane Potential Response To Wounding Protein Complex Assembly Cell Cycle Process Protein Oligomerization Negative Regulation Of Cell Cycle Potassium Ion Homeostasis Mitotic Cell Cycle Negative Regulation Of Chromosome Organization Locomotion G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Process Response To External Stimulus
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