MYL2 and CDC42BPA

Number of citations of the paper that reports this interaction (PMID 9418861)
59

Data Source:
HPRD (in vitro)

		MYL2	CDC42BPA
Gene Name		myosin, light chain 2, regulatory, cardiac, slow	CDC42 binding protein kinase alpha (DMPK-like)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Actin Cytoskeleton Myosin Complex Myofibril Sarcomere A Band	Cytoplasm Cell-cell Junction Cell Leading Edge Actomyosin Extracellular Vesicular Exosome
	Molecular Function	Actin Monomer Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Regulation Of Striated Muscle Contraction Post-embryonic Development Muscle Filament Sliding Negative Regulation Of Cell Growth Muscle Cell Fate Specification Muscle Fiber Development Cardiac Myofibril Assembly Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction	Microtubule Cytoskeleton Organization Protein Phosphorylation Nuclear Migration Cell Migration Actomyosin Structure Organization Actin Cytoskeleton Reorganization Intracellular Signal Transduction Regulation Of Catalytic Activity
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS		Alcohol consumption ( 21270382) Coronary heart disease ( 23364394) Drinking behavior ( 23364009) Gamma glutamyl transpeptidase ( 21909109) Glycemic traits ( 23575436) HDL cholesterol ( 21909109)
Protein-Protein Interactions		9 interactors: CDC42BPA GJB5 LRSAM1 MYOC NHP2 PAK2 PPP1R12C TRIM63 USP6	6 interactors: CDC42 LIMK1 LIMK2 MYL2 MYL9 PPP1R12C
Entrez ID		4633	8476
HPRD ID		01181	04562
Ensembl ID		ENSG00000111245	ENSG00000143776
Uniprot IDs		P10916 Q6IB42	F5H5N0 Q5VT25
PDB IDs
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Adaptation ERBB2-ERBB3 Signaling Pathway Skeletal Muscle Hypertrophy RRNA Pseudouridine Synthesis Ubiquitin-dependent Endocytosis ERBB2 Signaling Pathway Protein Catabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Spongiotrophoblast Differentiation Cellular Protein Modification Process Non-canonical Wnt Signaling Pathway Via JNK Cascade Skeletal Muscle Atrophy Non-canonical Wnt Signaling Pathway Via MAPK Cascade Striated Muscle Atrophy Muscle Atrophy Clustering Of Voltage-gated Sodium Channels Negative Regulation Of Execution Phase Of Apoptosis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Viral Budding Proteasomal Protein Catabolic Process Muscle System Process Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Stress Fiber Assembly Neuronal Ion Channel Clustering Nuclear Migration Negative Regulation Of Actin Filament Bundle Assembly	Ephrin Receptor Signaling Pathway Axon Guidance Heart Contraction Movement Of Cell Or Subcellular Component Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Actin Cytoskeleton Organization Cell Development Neuron Projection Morphogenesis Actin Filament-based Process Muscle Cell Fate Specification Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Projection Development Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of Muscle Contraction Cell Projection Morphogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Part Morphogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Actin Filament Branching Submandibular Salivary Gland Formation Neuron Development Cardiac Muscle Tissue Development Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Muscle Contraction Cell Morphogenesis Neuron Differentiation Cytoskeleton Organization Cell Projection Organization Establishment Of Golgi Localization Phagocytosis Muscle System Process Fc Receptor Signaling Pathway Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Cell Projection Organization Locomotion Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Fate Commitment Blood Circulation Positive Regulation Of Cellular Component Biogenesis Striated Muscle Tissue Development Neuron Fate Determination
Tagcloud ?		calcium carrier cav1 channel codes computational evidences gla herein knockdown messenger mgp mrfs mscs muscle myh3 myogenesis myogenic myosin myotube retinol satellite signifies t4 thyroxin transportation transthyretin ttr voltage
Tagcloud (Difference) ?		calcium carrier cav1 channel codes computational evidences gla herein knockdown messenger mgp mrfs mscs muscle myh3 myogenesis myogenic myosin myotube retinol satellite signifies t4 thyroxin transportation transthyretin ttr voltage
Tagcloud (Intersection) ?