VTA1 and LYST

Number of citations of the paper that reports this interaction (PMID 11984006)
18

Data Source:
BioGRID (two hybrid)

		VTA1	LYST
Gene Name		vesicle (multivesicular body) trafficking 1	lysosomal trafficking regulator
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Endosome Membrane Extracellular Vesicular Exosome	Cytosol Endomembrane System Microtubule Cytoskeleton Extrinsic Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Phospholipid Binding
	Biological Process	Protein Transport Viral Process Endosomal Transport Viral Life Cycle Membrane Organization	Neutrophil Mediated Immunity T Cell Mediated Immunity Phospholipid Metabolic Process Microtubule-based Process Lysosome Organization Blood Coagulation Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Response To Drug Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus Phospholipid Homeostasis
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS		Retinal vascular caliber ( 21060863)
Protein-Protein Interactions		17 interactors: APP CBS CDK4 CHMP5 DPPA2 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 NGFRAP1 RABAC1 RPIA SSSCA1 ZBTB16	24 interactors: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DGCR14 DNAJC14 EFS ESRRA HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521
Entrez ID		51534	1130
HPRD ID		09855	06060
Ensembl ID			ENSG00000143669
Uniprot IDs		E7ETQ7 Q9NP79	Q99698
PDB IDs		2LXL 2LXM
Enriched GO Terms of Interacting Partners?		Cell Division Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Lysosome Organization Positive Regulation Of Cell Cycle Phase Transition Cysteine Biosynthetic Process From Serine Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Homocysteine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Negative Regulation Of Cell Differentiation Organelle Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Synaptic Growth At Neuromuscular Junction Mast Cell Secretory Granule Organization Transsulfuration Regulation Of Mitotic Cell Cycle Vacuole Organization Collateral Sprouting In Absence Of Injury Cysteine Biosynthetic Process L-cysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Positive Regulation Of Mitotic Cell Cycle L-serine Catabolic Process Pentose-phosphate Shunt, Non-oxidative Branch Regulation Of Cell Cycle Process Positive Regulation Of NK T Cell Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Hydrogen Sulfide Metabolic Process Positive Regulation Of Peptidase Activity Endosome Transport Via Multivesicular Body Sorting Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Male Germ-line Stem Cell Asymmetric Division Regulation Of Cellular Protein Metabolic Process Axon Choice Point Recognition Protein Ubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cysteine Metabolic Process Secretion Of Lysosomal Enzymes Positive Regulation Of Cell Death Protein Modification By Small Protein Conjugation Regulation Of Response To Osmotic Stress Regulation Of Mitotic Spindle Assembly Regulation Of Signaling Homocysteine Metabolic Process Phospholipid Homeostasis Neuron Remodeling	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Mitochondrion Organization Protein Targeting Alternative MRNA Splicing, Via Spliceosome Regulation Of Mitochondrion Organization Centriole Replication Membrane Organization Gene Expression Protein Transport Centriole Assembly Establishment Of Protein Localization Epidermal Growth Factor Receptor Signaling Pathway Multicellular Organismal Development Centrosome Duplication ERBB Signaling Pathway Positive Regulation Of Transport Substantia Nigra Development Regulation Of Intracellular Transport Intrinsic Apoptotic Signaling Pathway Nervous System Development Positive Regulation Of Apoptotic Signaling Pathway MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Neural Nucleus Development Intracellular Protein Transport Centrosome Cycle Protein Localization Positive Regulation Of Intracellular Transport Apoptotic Process Establishment Of Localization In Cell Developmental Process Mitochondrial Translational Elongation Mitochondrial Translational Initiation Mitochondrial Translational Termination Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Programmed Cell Death Intracellular Transport Regulation Of Cellular Localization Cell Death Death Anatomical Structure Development Mitochondrial Translation System Development Midbrain Development Golgi Reassembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity RNA Splicing
Tagcloud ?		abscission atpase budding carboxyl cofactor compensatory coordinating cytokinesis endosomal enveloped escrt escrts helices hydrolysis input intergenic lip5 modulates multivesicular oligomer oligomerization rational sbp sorting stimulatory uncovered vps4 vse vsl	ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?		abscission atpase budding carboxyl cofactor compensatory coordinating cytokinesis endosomal enveloped escrt escrts helices hydrolysis input intergenic lip5 modulates multivesicular oligomer oligomerization rational sbp sorting stimulatory uncovered vps4 vse vsl	ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?