RBMX and CNNM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBMX	CNNM3
Description		RNA binding motif protein X-linked	cyclin and CBS domain divalent metal cation transport mediator 3
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GO Annotations	Cellular Component	Euchromatin Extracellular Space Nucleus Nucleoplasm Spliceosomal Complex Membrane Protein-containing Complex Organelle Supraspliceosomal Complex Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Plasma Membrane Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding Chromatin Binding RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Identical Protein Binding	Protein Binding Transmembrane Transporter Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation Transcription By RNA Polymerase II MRNA Processing Membrane Protein Ectodomain Proteolysis RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Homooligomerization Cellular Response To Interleukin-1	Monoatomic Ion Transport Magnesium Ion Homeostasis Transmembrane Transport
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Pediatric autoimmune diseases ( 26301688)	Bipolar disorder ( 31043756) Birth weight ( 31043758) Erectile dysfunction and prostate cancer treatment ( 20932654) Offspring birth weight ( 31043758)
Interacting Genes		51 interacting genes: APOBEC3C CCDC33 CEBPA CIRBP CLK1 CLK3 CMTM6 CNNM3 CSNK2A1 FOXP1 FXR2 HNRNPK IL7R ITSN2 JAK2 KHDRBS2 KHDRBS3 LINC01232 LNX1 MAGOHB MYPOP NABP1 NEIL3 NFE2L2 NXF1 NYX OGT PCBP2 PCDHB14 PRPF31 PRR3 PSMF1 PWARSN RAMAC RBM3 RBM7 RBMY1A1 RBMY1E RBMY1F RBMY1J ROBO3 SF1 SNRPA SOCS3 SORBS3 SREK1 SRPK2 STAT5A TRA2B XRN1 ZNF490	71 interacting genes: ACTN2 AGR2 AGR3 AKAP8L CALCOCO2 CARD10 CBY2 CCNDBP1 COG6 CYSRT1 EFEMP2 EXOSC8 FHL3 FHL5 GOLGA6L9 HNRNPK HOXA1 HSF2BP KHDRBS2 KHDRBS3 KPRP KRT31 KRT33B KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LZTS2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA P4HB PM20D2 PNMA1 PNMA2 PNMA3 PTP4A2 RBMX RBMY1F RBMY1J RBPMS RELA SRSF3 SSC4D TGM1 TNS2 TRIM27 UBE2G2 UBQLN2 USHBP1 VWC2 WWOX ZNF330 ZRANB1
Entrez ID		27316	26505
HPRD ID		02186	07419
Ensembl ID		ENSG00000147274	ENSG00000168763
Uniprot IDs		P38159	Q8NE01
PDB IDs		2MB0 2MKS	5K22 5K23 5K25 5TSR 6DFD 6MN6 6WUR
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Nucleic Acid Binding Spliceosomal Complex RNA Binding Regulation Of MRNA Metabolic Process MRNA Metabolic Process RNA Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing Positive Regulation Of RNA Splicing Nucleic Acid Metabolic Process RNA Processing Positive Regulation Of MRNA Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Nucleoplasm Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of RNA Metabolic Process Nucleus Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process Interleukin-6-mediated Signaling Pathway MRNA Splicing, Via Spliceosome Identical Protein Binding RNA Splicing, Via Transesterification Reactions Regulation Of Metabolic Process Interleukin-5-mediated Signaling Pathway Cytoplasmic Stress Granule Thrombopoietin-mediated Signaling Pathway Interleukin-3-mediated Signaling Pathway Interleukin-7-mediated Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Biosynthetic Process Response To Tumor Necrosis Factor Mammary Gland Epithelium Development Protein Domain Specific Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Leukocyte Apoptotic Process Negative Regulation Of Proteasomal Protein Catabolic Process Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Via JAK-STAT	Intermediate Filament Keratin Filament Identical Protein Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Protein Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Structural Constituent Of Skin Epidermis Nucleic Acid Binding Cytosol Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing
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