POLR2A and ITCH

  • Number of citations of the paper that reports this interaction (PMID 16055720)
  • 52
  • Data Source:
  • HPRD (in vitro, in vivo)

POLR2A

ITCH

Gene Name polymerase (RNA) II (DNA directed) polypeptide A, 220kDa itchy E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 100 interactors: ABL1 ACTB ACTL6A ATM BARD1 BRCA1 CASP10 CCNH CCNK CCNL2 CCNT1 CDC14A CDK12 CDK7 CDK8 CDK9 CPSF1 CPSF2 CPSF3 CREBBP CSH2 CSNK2A1 CSTF1 CSTF2 CTCF CTD CTDP1 CTDSP1 CTDSP2 DHX9 ELL ERCC5 ERCC6 ERG FCP1 FUS GRB2 GTF2B GTF2E1 GTF2H4 HIST1H1C HNRNPF HNRNPU HTATSF1 ITCH IWS1 KAT2B KLK2 KMT2D LEO1 MCM3 MED21 MNAT1 MYC NEDD4 NELFA NONO NR0B2 PCIF1 PHF8 PIN1 POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2K POLR2L PPIG PPP1CA PQBP1 PRPF19 RECQL5 SAFB SETD2 SMN1 SMN2 SMURF1 SND1 SUB1 SUPT5H TAF10 TBP TCEA1 TCEB3 TCERG1 TRAK1 TRAM2 U2AF2 UBC UBE2L3 UPF1 WAC WWP2 XAB2 XRCC5 ZNF74 80 interactors: ARID1A ARRB2 ARRDC1 ARRDC3 ATN1 BECN1 CBL CBLC CDC34 CPSF6 CPSF7 CSNK2A1 CXCR4 CYLD DAZAP1 DTX1 DTX3L DVL2 ERBB4 EWSR1 FYN GNAI2 HNRNPL HNRNPUL1 JUN LAPTM5 LATS1 LITAF MAP2K4 MAPK8 MLANA N4BP1 NDFIP2 NEDD9 NFE2 NOTCH1 NUDT21 NUMB PABPC1 POLR2A POLR2B POLR2C POLR2E POU5F1 PRKACA RIPK1 RNF11 RPAP2 RPAP3 SCNN1A SCNN1B SF1 SGK3 SH3GL2 SMAD2 SMAD3 SMARCC1 SMARCC2 SMARCE1 SNX9 SPG20 STAM2 TP73 TRPC4 TRPV1 TRPV4 TXNIP UBAP2 UBAP2L UBC UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2G1 UBE2J2 UBE2K UBE2L3 URI1 WBP2
Entrez ID 5430 83737
HPRD ID 08916 07565
Ensembl ID ENSG00000181222 ENSG00000078747
Uniprot IDs P24928 Q96J02
PDB IDs 2GHQ 2GHT 2LTO 3D9K 3D9L 3D9M 3D9N 3D9O 3D9P 2DMV 2KYK 2NQ3 2P4R 2YSF 3TUG
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actb  appropriately  benchmark  chosen  confounding  gapdh  hormonal  hprt1  hyperglycemia  hyperglycemic  lean  myocardium  normalization  normalized  obesity  ppia  predisposition  reference  reproducibility  rpl13a  scrutiny  sdha  select  stably  tbp  tfrc  underline  ywhag  zucker 
ascertain  benzoin  biweekly  break  clearance  clinic  convenience  eradicating  erosions  ethanol  individual  irritation  ns  paint  pb  pe  penile  penis  podophyllin  regimens  resin  sequentially  superficial  supervised  tincture  treated  wart  warts  week 
Tagcloud (Difference) ?
actb  appropriately  benchmark  chosen  confounding  gapdh  hormonal  hprt1  hyperglycemia  hyperglycemic  lean  myocardium  normalization  normalized  obesity  ppia  predisposition  reference  reproducibility  rpl13a  scrutiny  sdha  select  stably  tbp  tfrc  underline  ywhag  zucker 
ascertain  benzoin  biweekly  break  clearance  clinic  convenience  eradicating  erosions  ethanol  individual  irritation  ns  paint  pb  pe  penile  penis  podophyllin  regimens  resin  sequentially  superficial  supervised  tincture  treated  wart  warts  week 
Tagcloud (Intersection) ?