PML and SIRT1

  • Number of citations of the paper that reports this interaction (PMID 12006491)
  • 186
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

PML

SIRT1

Gene Name promyelocytic leukemia sirtuin 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 101 interactors: ADH1B ANKRD2 ARID3A ARNT ATF2 ATXN1 AURKA AXIN1 BANP BCL2 BCL6 CASP8AP2 CCNT1 CDK1 CDK2 CDK6 CHFR CREBBP CSNK2A1 DAXX EGFR EIF4E ELF4 EP300 FOS GATA2 HDAC1 HDAC2 HDAC3 HHEX HIPK2 HTT KAT5 KAT6A MAPK11 MAPK14 MDM2 MED7 MXD1 MYB MYC NCOA2 NCOR1 NCOR2 NFKB1 NR3C1 NR4A1 PAWR PAXIP1 PCBD2 PIAS1 PIAS2 PIN1 PLAGL1 PLSCR1 POLR2E PPARG PSMA3 RARA RB1 RBX1 RELA RNF111 RNF125 RNF4 RPL11 RXRA SENP2 SH3GL1 SIAH2 SIN3A SIRT1 SKI SMAD3 SP1 SP100 SRF STAT3 SUMO1 SUMO2 SUMO3 SUV39H1 SYNE2 TDG TERF2IP TGFBR1 TGFBR2 TGIF1 THRA TOPBP1 TP53 TP63 TP73 TRIM24 TRIM27 TRIM69 UBE2I UBE2U UBE3A ZBTB16 ZFYVE9 47 interactors: AKT1 ARNTL BCL11A BHLHE41 CDK6 CSNK2B CTTN EP300 ESRRA FOS FOXO1 FOXO3 GAPDH HES1 HEY2 HIC1 HIST1H1B HIST1H3A HNF4A IRS2 MAPK8 MAPT MYCN NBN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARGC1A PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SNW1 SREBF1 STK11 STK4 TP53 UBE2I VDR
Entrez ID 5371 23411
HPRD ID 00023 08381
Ensembl ID ENSG00000140464 ENSG00000096717
Uniprot IDs P29590 A8K128 B0QZ35 E9PC49 Q96EB6
PDB IDs 1BOR 4I5I
Enriched GO Terms of Interacting Partners?
Tagcloud ?
anthracycline  apl  approaches  appropriately  arsenic  corepressors  curable  cure  deacetylase  effectiveness  explain  explains  incorporation  minority  oncogenes  pathogenetic  plzf  progranulocytic  promoters  ra  rar  recruit  refinement  relapsed  repression  safe  timed  trioxide  vast 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Difference) ?
anthracycline  apl  approaches  appropriately  arsenic  corepressors  curable  cure  effectiveness  explain  explains  incorporation  minority  oncogenes  pathogenetic  plzf  progranulocytic  promoters  ra  rar  recruit  refinement  relapsed  repression  safe  timed  trioxide  vast 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Intersection) ?
deacetylase