HOXB7 and PKNOX1

Number of citations of the paper that reports this interaction (PMID 9366523)
4

Data Source:
HPRD (in vivo)

		HOXB7	PKNOX1
Gene Name		homeobox B7	PBX/knotted 1 homeobox 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Transcription Factor Complex Cytoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding	Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Anterior/posterior Pattern Specification Myeloid Cell Differentiation Embryonic Skeletal System Morphogenesis Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis	Angiogenesis Transcription From RNA Polymerase II Promoter T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS			Biochemical measures ( 19260141) Cognitive performance ( 20125193) Information processing speed ( 21130836)
Protein-Protein Interactions		13 interactors: APP CLK3 CREBBP CSNK2A1 EP300 GMNN HOXB6 IRAK3 NFKBIA PARP1 PBX1 PKNOX1 XRCC6	15 interactors: APP HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 MEIS1 PAX6 PBX1 PBX2 POU2F1 RFX3 TLX1 VPS37C ZBTB3
Entrez ID		3217	5316
HPRD ID		00850	03653
Ensembl ID		ENSG00000260027	ENSG00000160199
Uniprot IDs		P09629	E7EPN6 P55347 Q6PKH2 Q96I87
PDB IDs			1X2N
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Immune System Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Type I Interferon Production Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Type I Interferon Production Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process N-terminal Peptidyl-lysine Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Metabolic Process Regulation Of Cytokine Production RNA Biosynthetic Process Regulation Of Binding Anatomical Structure Morphogenesis Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Multicellular Organismal Development N-terminal Protein Amino Acid Acetylation Anatomical Structure Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cytokine Production Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Homeostatic Process Organ Development Innate Immune Response Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Notch Signaling Pathway System Development Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Cell Cycle N-terminal Protein Amino Acid Modification Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Heat Regulation Of Cellular Process Response To Temperature Stimulus Viral Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process	Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Pattern Specification Process Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Embryonic Morphogenesis Organ Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organ Development Anterior/posterior Pattern Specification Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Embryonic Skeletal System Development Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Anatomical Structure Development Cellular Nitrogen Compound Metabolic Process Embryo Development System Development Embryonic Organ Development Developmental Process Nitrogen Compound Metabolic Process Cell Differentiation Positive Regulation Of Metabolic Process Skeletal System Development Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Skeletal System Morphogenesis Regulation Of Metabolic Process Embryonic Organ Morphogenesis Proximal/distal Pattern Formation Cell Development Chordate Embryonic Development Negative Regulation Of Neuron Differentiation Embryo Development Ending In Birth Or Egg Hatching Transcription From RNA Polymerase II Promoter Rhombomere Development
Tagcloud ?		acquisition autonomous beta2 depleted dramatically emt knockdown luciferase m2 macrophage mb mda mesenchymal metastasis mmtv neu overexpressing pharmacologic phenotypes promoted promotes relevance reversed smad3 tam tams tgf transgenic	219a 5p aberration amongst confer consortium dys effectors enrichment epha4 epigenetic esr1 hsa ipa mcic microrna micrornas mind neuropsychological predicted psychiatric ranked respective schizophrenia searched sets strengthened thousands transcriptionally
Tagcloud (Difference) ?		acquisition autonomous beta2 depleted dramatically emt knockdown luciferase m2 macrophage mb mda mesenchymal metastasis mmtv neu overexpressing pharmacologic phenotypes promoted promotes relevance reversed smad3 tam tams tgf transgenic	219a 5p aberration amongst confer consortium dys effectors enrichment epha4 epigenetic esr1 hsa ipa mcic microrna micrornas mind neuropsychological predicted psychiatric ranked respective schizophrenia searched sets strengthened thousands transcriptionally
Tagcloud (Intersection) ?