HOXB7 and HOXB6

Number of citations of the paper that reports this interaction (PubMedID 7729685)
0

Data Source:
HPRD (in vivo)

		HOXB7	HOXB6
Description		homeobox B7	homeobox B6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Nuclear Body	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Embryonic Skeletal System Morphogenesis Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Erythrocyte Homeostasis Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development
Pathways
Drugs
Diseases
GWAS		Hypertension ( 27618447) LDL cholesterol levels ( 32203549) Mean arterial pressure ( 30487518) Pulse pressure ( 27618447 28135244) Systolic blood pressure ( 27618447 30487518)	Childhood body mass index ( 26604143) Hemoglobin ( 32888494)
Interacting Genes		13 interacting genes: APP CLK3 CREBBP CSNK2A1 EP300 GMNN HOXB6 IRAK3 NFKBIA PARP1 PBX1 PKNOX1 XRCC6	17 interacting genes: ALX4 CLK3 CREBBP CSNK2B EP300 GYS1 HOXB7 KRT15 NEK6 NTAQ1 PKNOX1 PLSCR1 SAT1 SRPK2 TCEAL1 TCF21 TEKT5
Entrez ID		3217	3216
HPRD ID		00850	00849
Ensembl ID		ENSG00000260027	ENSG00000108511
Uniprot IDs		P09629	P17509
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Regulator Complex Regulation Of Innate Immune Response Regulation Of Gene Expression Immune System Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Protein Localization To Nucleus Damaged DNA Binding Activation Of Innate Immune Response Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Defense Response Histone H3K27 Acetyltransferase Activity Regulation Of Transcription By RNA Polymerase II Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Defense Response Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Innate Immune Response Regulation Of Immune Response Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Recombinational Repair Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Protein-DNA Complex Negative Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Cellular Response To Radiation Positive Regulation Of DNA-templated Transcription Hemopoiesis Innate Immune Response-activating Signaling Pathway DNA-binding Transcription Factor Binding Activation Of Immune Response Canonical NF-kappaB Signal Transduction Positive Regulation Of RNA Metabolic Process Response To Radiation Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Double-strand Break Repair Innate Immune Response Activating Cell Surface Receptor Signaling Pathway	Transcription Regulator Complex Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K27 Acetyltransferase Activity Chromatin Peptide Lactyltransferase (CoA-dependent) Activity Nucleus Negative Regulation Of Viral Process N-terminal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Regulation Of Cellular Response To Heat Positive Regulation Of Transcription By RNA Polymerase II Acetyltransferase Activity Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Viral Life Cycle Angiogenesis Histone Acetyltransferase Complex Embryonic Organ Morphogenesis Nucleoplasm Anatomical Structure Morphogenesis Protein-lysine-acetyltransferase Activity Nuclear Androgen Receptor Binding Protein Phosphorylation Regulation Of Viral Process Acyltransferase Activity Phosphorylation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Activity Protein Acetylation Regulation Of Androgen Receptor Signaling Pathway Protein Modification Process Protein Serine/threonine Kinase Activity Anterior/posterior Pattern Specification Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transferase Activity Embryonic Morphogenesis RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding Tau Protein Binding Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity
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