PI4KB and MYCBP2

Number of citations of the paper that reports this interaction (PubMedID 21653829)
54

Data Source:
BioGRID (two hybrid)

		PI4KB	MYCBP2
Description		phosphatidylinositol 4-kinase beta	MYC binding protein 2
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Membrane Rough Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Axon Cell Projection
	Molecular Function	Nucleotide Binding 1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity 14-3-3 Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Transferase Activity Small GTPase Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Receptor-mediated Endocytosis Lysosome Organization Signal Transduction Phosphatidylinositol Phosphate Biosynthetic Process Phosphatidylinositol-mediated Signaling Inner Ear Development	Axon Guidance Motor Neuron Axon Guidance Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Rhythmic Process Cell Morphogenesis Involved In Neuron Differentiation Neuromuscular Process Regulation Of Cytoskeleton Organization Axon Development Protein K48-linked Ubiquitination Regulation Of Axon Guidance
Pathways		Synthesis of PIPs at the Golgi membrane
Drugs		Fostamatinib
Diseases
GWAS		Body mass index ( 26426971) Gut microbiota (functional units) ( 27694959)	Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		5 interacting genes: MYCBP2 NCS1 YWHAB YWHAG YWHAQ	50 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 BTG3 CALM1 CD81 CEBPA CFL1 CUEDC2 DHRS4L2 DSCR9 DYRK1A ERBB3 FHL3 FSCN1 HSP90AB1 HUNK IGFBP6 LCOR LDHB LSM14A MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 RSPH1 SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ
Entrez ID		5298	23077
HPRD ID		11805	10104
Ensembl ID		ENSG00000143393	ENSG00000005810
Uniprot IDs		A0A0B4J1S8 Q9UBF8	O75592
PDB IDs		2N73 4D0L 4D0M 4WAE 4WAG 5C46 5C4G 5EUQ 5FBL 5FBQ 5FBR 5FBV 5FBW 5LX2 5NAS 6GL3 8Q6F 8Q6G 8Q6H 8VOF	5O6C 6T7F
Enriched GO Terms of Interacting Partners?		Protein Domain Specific Binding Protein Targeting Protein Sequestering Activity Focal Adhesion Identical Protein Binding Protein Kinase C Inhibitor Activity	Cytoplasm Intracellular Signal Transduction
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