PIM1 and CDKN1A

  • Number of citations of the paper that reports this interaction (PMID 12431783)
  • 46
  • Data Source:
  • HPRD (in vivo, in vitro)

PIM1

CDKN1A

Gene Name Pim-1 proto-oncogene, serine/threonine kinase cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 29 interactors: ABCB1 APP BAD BANP BEND7 CBX1 CBX3 CDC20 CDC25A CDKN1A EPHA3 FH FXR2 HEXIM2 HIST2H3C HIST3H3 HSP90AA1 MARK3 NFATC1 NHLH1 NUMA1 PPP2R4 PTPRO SHMT1 SKP2 SND1 SNX6 TFPT ZBTB1 176 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 AKT1 ALAS1 ANGPT2 APLP1 APP ATP5B ATP6V1A ATXN3 BAD BAG6 BCCIP C1orf123 CASP3 CCDC85B CCNA1 CCNA2 CCNB1 CCNB2 CCND1 CCND2 CCND3 CCNE1 CCNE2 CCT7 CDC42 CDC45 CDC5L CDC6 CDC7 CDK1 CDK14 CDK2 CDK3 CDK4 CDK6 CEBPA CELF3 CENPB CHGB CIZ1 CLEC3B COL4A5 COPS6 CPNE2 CPNE6 CSAD CSNK2A1 CSNK2B CTSB DAPK3 DDAH2 DEAF1 DOCK7 DYNC1I1 EEF1A1 EP300 ESR1 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GADD45A GADD45B GADD45G GAPDH GCKR GDF9 GET4 GMNN GNB2 GNB2L1 GNB5 HADHB HDAC1 HDAC11 HDAC2 HDAC4 HDAC6 HERC5 HIST1H1B HMGXB3 HNRNPK HOXD8 HPD IKBKG IKZF3 ING5 INPP5K KLHL23 KMT2B KRT31 LATS2 LRIF1 MAP3K5 MAPK8 MCM10 MED31 MSH2 NGFR NKD2 NMRK2 NOV NPM1 NPRL2 NR1H2 NRBP1 OTUB1 PARP1 PCNA PDE4DIP PDHB PIM1 PKM POLD2 PSMA3 QARS RAB1A RAI1 RB1 RBBP4 RBM48 RNF126 RNF144B RPL18 RPL35 RPS2 S100A8 SDF4 SET SETDB1 SIPA1 SKP2 SLC25A11 SP110 SPRED1 STAT3 SUMO3 TAF5L TCF4 TEX11 TK1 TLE1 TMSB4X TNIP1 TNIP2 TRAF1 TRIM54 TRMT2A TSG101 TTLL5 TUBA1A TUBB2B TUBB3 TXN TXNDC11 UBC UBE2D1 UNC119 USP4 VIM VPS51 WDR73 WIZ XRCC6 YWHAQ ZBTB16 ZBTB48 ZNF135 ZNF431
Entrez ID 5292 1026
HPRD ID 01292 00298
Ensembl ID ENSG00000137193 ENSG00000124762
Uniprot IDs P11309 J3KQV0 P38936
PDB IDs 1XQZ 1XR1 1XWS 1YHS 1YI3 1YI4 1YWV 1YXS 1YXT 1YXU 1YXV 1YXX 2BIK 2BIL 2BZH 2BZI 2BZJ 2BZK 2C3I 2J2I 2O3P 2O63 2O64 2O65 2OBJ 2OI4 2XIX 2XIY 2XIZ 2XJ0 2XJ1 2XJ2 3A99 3BGP 3BGQ 3BGZ 3BWF 3C4E 3CXW 3CY2 3CY3 3DCV 3F2A 3JPV 3JXW 3JY0 3JYA 3MA3 3QF9 3R00 3R01 3R02 3R04 3T9I 3UIX 3UMW 3UMX 3VBQ 3VBT 3VBV 3VBW 3VBX 3VBY 3VC4 4A7C 4ALU 4ALV 4ALW 4AS0 4DTK 4ENX 4ENY 4GW8 4JX3 4JX7 4K0Y 4K18 4K1B 4MBI 1AXC 2ZVV 2ZVW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bm6  bx1  chimera  construct  ectopic  ectopically  effectors  epo  erb1  erythropoietin  fdc2  fdcp1  gata  interactive  kit  mitogenesis  mitogenic  mo7e  notion  opposing  presently  progenitor  responsiveness  scf  subdomain  subline  synergy  ways 
antigen  arf  cd24  competitively  context  e6  glioma  hairpin  inactivation  mdm2  mutated  mutates  nearly  npm  oncogenes  overexpressed  p21  papilloma  prevents  prostate  retard  reveal  shrna  silencing  silico  somatic  sv40  tp53  viral 
Tagcloud (Difference) ?
bm6  bx1  chimera  construct  ectopic  ectopically  effectors  epo  erb1  erythropoietin  fdc2  fdcp1  gata  interactive  kit  mitogenesis  mitogenic  mo7e  notion  opposing  presently  progenitor  responsiveness  scf  subdomain  subline  synergy  ways 
antigen  arf  cd24  competitively  context  e6  glioma  hairpin  inactivation  mdm2  mutated  mutates  nearly  npm  oncogenes  overexpressed  p21  papilloma  prevents  prostate  retard  reveal  shrna  silencing  silico  somatic  sv40  tp53  viral 
Tagcloud (Intersection) ?