PIM1 and SKP2

  • Number of citations of the paper that reports this interaction (PMID 20663873)
  • 5
  • Data Source:
  • BioGRID (affinity chromatography technology, enzymatic study)

PIM1

SKP2

Gene Name Pim-1 proto-oncogene, serine/threonine kinase S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 29 interactors: ABCB1 APP BAD BANP BEND7 CBX1 CBX3 CDC20 CDC25A CDKN1A EPHA3 FH FXR2 HEXIM2 HIST2H3C HIST3H3 HSP90AA1 MARK3 NFATC1 NHLH1 NUMA1 PPP2R4 PTPRO SHMT1 SKP2 SND1 SNX6 TFPT ZBTB1 54 interactors: AKT1 BTG1 BTG2 CCNA2 CCNE1 CCNT1 CDC14B CDC34 CDH1 CDK2 CDK9 CDKN1A CDKN1B CDKN1C CDT1 CEBPA CHKA CKS1B CKS1BP7 CUL1 CUL4A DDB1 DUSP1 E2F1 ELF4 ESR1 FZR1 GPS1 KPNA1 KPNA6 MYB MYBL2 MYC NLK ORC1 PFDN1 PIM1 PSMD9 RAG2 RB1 RBL2 RND3 SIRT4 SIRT6 SKP1 SMAD4 TAL1 TCF3 TRIM21 UBB VHL WEE1 YWHAB YY1
Entrez ID 5292 6502
HPRD ID 01292 03256
Ensembl ID ENSG00000137193 ENSG00000145604
Uniprot IDs P11309 Q13309
PDB IDs 1XQZ 1XR1 1XWS 1YHS 1YI3 1YI4 1YWV 1YXS 1YXT 1YXU 1YXV 1YXX 2BIK 2BIL 2BZH 2BZI 2BZJ 2BZK 2C3I 2J2I 2O3P 2O63 2O64 2O65 2OBJ 2OI4 2XIX 2XIY 2XIZ 2XJ0 2XJ1 2XJ2 3A99 3BGP 3BGQ 3BGZ 3BWF 3C4E 3CXW 3CY2 3CY3 3DCV 3F2A 3JPV 3JXW 3JY0 3JYA 3MA3 3QF9 3R00 3R01 3R02 3R04 3T9I 3UIX 3UMW 3UMX 3VBQ 3VBT 3VBV 3VBW 3VBX 3VBY 3VC4 4A7C 4ALU 4ALV 4ALW 4AS0 4DTK 4ENX 4ENY 4GW8 4JX3 4JX7 4K0Y 4K18 4K1B 4MBI 1FQV 1FS1 1FS2 1LDK 2ASS 2AST
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bm6  bx1  chimera  construct  ectopic  ectopically  effectors  epo  erb1  erythropoietin  fdc2  fdcp1  gata  interactive  kit  mitogenesis  mitogenic  mo7e  notion  opposing  presently  progenitor  responsiveness  scf  subdomain  subline  synergy  ways 
antisense  box  cdc53  cdk2  cip1  complex  cul  cullin  deregulation  e3  g1  hallmark  kip1  ligase  lived  member  oligodeoxynucleotides  oligonucleotides  p19  p21  p27  p45  proteolysis  raises  scf  skp1  transformed  ubiquitin  waf1 
Tagcloud (Difference) ?
bm6  bx1  chimera  construct  ectopic  ectopically  effectors  epo  erb1  erythropoietin  fdc2  fdcp1  gata  interactive  kit  mitogenesis  mitogenic  mo7e  notion  opposing  presently  progenitor  responsiveness  subdomain  subline  synergy  ways 
antisense  box  cdc53  cdk2  cip1  complex  cul  cullin  deregulation  e3  g1  hallmark  kip1  ligase  lived  member  oligodeoxynucleotides  oligonucleotides  p19  p21  p27  p45  proteolysis  raises  skp1  transformed  ubiquitin  waf1 
Tagcloud (Intersection) ?
scf