PGR and POU2F2

Number of citations of the paper that reports this interaction (PMID 10480874)
15

Data Source:
BioGRID (pull down)

		PGR	POU2F2
Gene Name		progesterone receptor	POU class 2 homeobox 2
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrial Outer Membrane	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Receptor Binding Steroid Binding Protein Binding Zinc Ion Binding Enzyme Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Domain Specific Binding Sequence-specific DNA Binding
	Biological Process	Ovulation From Ovarian Follicle Epithelial Cell Maturation Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Cell-cell Signaling Gene Expression Negative Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Epithelial Cell Proliferation Progesterone Receptor Signaling Pathway Tertiary Branching Involved In Mammary Gland Duct Morphogenesis	Mature B Cell Differentiation Immunoglobulin Secretion Involved In Immune Response Transcription From RNA Polymerase II Promoter Humoral Immune Response Positive Regulation Of Transcription, DNA-templated Cell Maturation
Pathways		Nuclear signaling by ERBB4 Generic Transcription Pathway Nuclear Receptor transcription pathway Signaling by ERBB4
Drugs		Etonogestrel Desogestrel Megestrol Levonorgestrel Dydrogesterone Progesterone Fluticasone Propionate Medroxyprogesterone Norethindrone Ethynodiol Diacetate Mifepristone Norgestimate Drospirenone Danazol Allylestrenol Methyltrienolone Tanaproget Norelgestromin
Diseases
GWAS
Protein-Protein Interactions		49 interactors: ANP32A APEX2 ARID1A BATF3 BCAS2 BRCA1 CCNA1 CCNA2 CDC25B CDK2 COPS5 CSNK2A1 CUEDC2 DAP3 DDX54 ESR1 FKBP5 HMGB1 HMGB2 JDP2 KAT2B KLF9 NCOA1 NCOA3 NR0B1 PIAS1 PIAS2 PIAS3 POU2F1 POU2F2 PRKDC PRMT2 RBM23 RBM39 RELA RNF4 SMARCD1 SMARCE1 SNW1 SORBS1 SRC TAF1B TDG TRIM24 UBE3A UBR5 XRCC5 XRCC6 ZBTB17	13 interactors: AR ESR1 GAPDH HMGA1 HMGB2 MNAT1 NR3C1 PGR POU2AF1 RXRA TBP TXNRD1 XRCC6
Entrez ID		5241	5452
HPRD ID		07077	01251
Ensembl ID		ENSG00000082175	ENSG00000028277
Uniprot IDs		P06401 Q8TDS3	B5ME60 E9PNC9 P09086
PDB IDs		1A28 1E3K 1SQN 1SR7 1ZUC 2C7A 2OVH 2OVM 2W8Y 3D90 3G8O 3HQ5 3KBA 3ZR7 3ZRA 3ZRB 4A2J 4APU	1HDP
Enriched GO Terms of Interacting Partners?		Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Androgen Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Hormone Chromosome Organization Regulation Of Cellular Process Chromatin Modification Cellular Response To Stimulus Response To Stimulus Chromatin Organization Cellular Response To Hormone Stimulus Regulation Of Cell Cycle Response To Steroid Hormone Organelle Organization Cellular Response To Organic Substance Intracellular Estrogen Receptor Signaling Pathway	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Cellular Response To Steroid Hormone Stimulus RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Lipid Intracellular Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Response To Steroid Hormone Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Reproductive Process Multicellular Organismal Reproductive Process Negative Regulation Of Biosynthetic Process Response To Lipid Multicellular Organism Reproduction Response To Organic Cyclic Compound Gland Development Reproductive Structure Development Reproductive System Development Mammary Gland Duct Morphogenesis Response To Hormone Prostate Gland Development
Tagcloud ?		antiperoxidase automatic automatically bauds computerized cutting dab get haemathoxyline immunocytochemistry immunoquantification immunoscore isc obtaining pixel plot recurrences reproducible robustness scene segmentation semilogarithmic simplicity sum summarizes telemedicine telequantification thresholds videophones	aberrations aggregate arid1a broaden carries constitutes deregulation disomy dnmt3b evolving exclusive exome fl follicular hist1h1 hodgkin implicating irf8 linker massively mutated mutually oct2 profiling recurrently stably substantially transduced uniparental
Tagcloud (Difference) ?		antiperoxidase automatic automatically bauds computerized cutting dab get haemathoxyline immunocytochemistry immunoquantification immunoscore isc obtaining pixel plot recurrences reproducible robustness scene segmentation semilogarithmic simplicity sum summarizes telemedicine telequantification thresholds videophones	aberrations aggregate arid1a broaden carries constitutes deregulation disomy dnmt3b evolving exclusive exome fl follicular hist1h1 hodgkin implicating irf8 linker massively mutated mutually oct2 profiling recurrently stably substantially transduced uniparental
Tagcloud (Intersection) ?