PGR and DDX54

Number of citations of the paper that reports this interaction (PMID 12466272)
14

Data Source:
HPRD (in vitro)

		PGR	DDX54
Gene Name		progesterone receptor	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrial Outer Membrane	Nucleus Nucleolus Membrane
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Receptor Binding Steroid Binding Protein Binding Zinc Ion Binding Enzyme Binding	Transcription Corepressor Activity ATP-dependent RNA Helicase Activity Receptor Binding ATP Binding Estrogen Receptor Binding Poly(A) RNA Binding
	Biological Process	Ovulation From Ovarian Follicle Epithelial Cell Maturation Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Cell-cell Signaling Gene Expression Negative Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Epithelial Cell Proliferation Progesterone Receptor Signaling Pathway Tertiary Branching Involved In Mammary Gland Duct Morphogenesis	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing RNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		Nuclear signaling by ERBB4 Generic Transcription Pathway Nuclear Receptor transcription pathway Signaling by ERBB4
Drugs		Etonogestrel Desogestrel Megestrol Levonorgestrel Dydrogesterone Progesterone Fluticasone Propionate Medroxyprogesterone Norethindrone Ethynodiol Diacetate Mifepristone Norgestimate Drospirenone Danazol Allylestrenol Methyltrienolone Tanaproget Norelgestromin
Diseases
GWAS			Response to fenofibrate (adiponectin levels) ( 23149075)
Protein-Protein Interactions		49 interactors: ANP32A APEX2 ARID1A BATF3 BCAS2 BRCA1 CCNA1 CCNA2 CDC25B CDK2 COPS5 CSNK2A1 CUEDC2 DAP3 DDX54 ESR1 FKBP5 HMGB1 HMGB2 JDP2 KAT2B KLF9 NCOA1 NCOA3 NR0B1 PIAS1 PIAS2 PIAS3 POU2F1 POU2F2 PRKDC PRMT2 RBM23 RBM39 RELA RNF4 SMARCD1 SMARCE1 SNW1 SORBS1 SRC TAF1B TDG TRIM24 UBE3A UBR5 XRCC5 XRCC6 ZBTB17	11 interactors: APP CSNK2A1 ESR1 ESR2 NEDD4 NEDD4L NR3C1 PGR POLR2G SEMA4A TMED9
Entrez ID		5241	79039
HPRD ID		07077	13129
Ensembl ID		ENSG00000082175	ENSG00000123064
Uniprot IDs		P06401 Q8TDS3	Q8TDD1
PDB IDs		1A28 1E3K 1SQN 1SR7 1ZUC 2C7A 2OVH 2OVM 2W8Y 3D90 3G8O 3HQ5 3KBA 3ZR7 3ZRA 3ZRB 4A2J 4APU
Enriched GO Terms of Interacting Partners?		Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Androgen Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Hormone Chromosome Organization Regulation Of Cellular Process Chromatin Modification Cellular Response To Stimulus Response To Stimulus Chromatin Organization Cellular Response To Hormone Stimulus Regulation Of Cell Cycle Response To Steroid Hormone Organelle Organization Cellular Response To Organic Substance Intracellular Estrogen Receptor Signaling Pathway	Transcription Initiation From RNA Polymerase II Promoter Intracellular Steroid Hormone Receptor Signaling Pathway Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Steroid Hormone Mediated Signaling Pathway Cell Development Hormone-mediated Signaling Pathway Gland Morphogenesis Cellular Response To Steroid Hormone Stimulus Transcription From RNA Polymerase II Promoter Anatomical Structure Morphogenesis Progesterone Receptor Signaling Pathway Mammary Gland Duct Morphogenesis Glucocorticoid Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Mammary Gland Branching Involved In Pregnancy Mammary Gland Morphogenesis Rhythmic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of Sodium Ion Transport Mammary Gland Epithelium Development Ovulation Cycle Process Regulation Of RNA Metabolic Process RNA Metabolic Process Female Gonad Development Vagina Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Transcription, DNA-templated Uterus Development Cell Differentiation Positive Regulation Of Metabolic Process Cellular Response To Organic Cyclic Compound Gene Expression Cellular Response To Stimulus RNA Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Cellular Response To Lipid Regulation Of Nitrogen Compound Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Cell Maturation Epithelial Cell Maturation Female Genitalia Development Response To Steroid Hormone Signal Transduction Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Organ Morphogenesis Gland Development Mammary Gland Development
Tagcloud ?		antiperoxidase automatic automatically bauds computerized cutting dab get haemathoxyline immunocytochemistry immunoquantification immunoscore isc obtaining pixel plot recurrences reproducible robustness scene segmentation semilogarithmic simplicity sum summarizes telemedicine telequantification thresholds videophones	abundantly acidic adaptor analyzing comprehensive consists cysteine dead dimer eap30 ell epsilon glial hek293 immobilized interacting interactors isoforms keratin krt18 mapkapk2 microarray partners polypeptide powerful sh3 stac unreported verified
Tagcloud (Difference) ?		antiperoxidase automatic automatically bauds computerized cutting dab get haemathoxyline immunocytochemistry immunoquantification immunoscore isc obtaining pixel plot recurrences reproducible robustness scene segmentation semilogarithmic simplicity sum summarizes telemedicine telequantification thresholds videophones	abundantly acidic adaptor analyzing comprehensive consists cysteine dead dimer eap30 ell epsilon glial hek293 immobilized interacting interactors isoforms keratin krt18 mapkapk2 microarray partners polypeptide powerful sh3 stac unreported verified
Tagcloud (Intersection) ?