PGR and ZBTB17

Number of citations of the paper that reports this interaction (PMID 11117529)
28

Data Source:
HPRD (in vitro)

		PGR	ZBTB17
Gene Name		progesterone receptor	zinc finger and BTB domain containing 17
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrial Outer Membrane	Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Receptor Binding Steroid Binding Protein Binding Zinc Ion Binding Enzyme Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Ovulation From Ovarian Follicle Epithelial Cell Maturation Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Cell-cell Signaling Gene Expression Negative Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Epithelial Cell Proliferation Progesterone Receptor Signaling Pathway Tertiary Branching Involved In Mammary Gland Duct Morphogenesis	Gastrulation With Mouth Forming Second Transcription, DNA-templated Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Ectoderm Development Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated
Pathways		Nuclear signaling by ERBB4 Generic Transcription Pathway Nuclear Receptor transcription pathway Signaling by ERBB4	IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs		Etonogestrel Desogestrel Megestrol Levonorgestrel Dydrogesterone Progesterone Fluticasone Propionate Medroxyprogesterone Norethindrone Ethynodiol Diacetate Mifepristone Norgestimate Drospirenone Danazol Allylestrenol Methyltrienolone Tanaproget Norelgestromin
Diseases
GWAS			Dilated cardiomyopathy ( 21459883)
Protein-Protein Interactions		49 interactors: ANP32A APEX2 ARID1A BATF3 BCAS2 BRCA1 CCNA1 CCNA2 CDC25B CDK2 COPS5 CSNK2A1 CUEDC2 DAP3 DDX54 ESR1 FKBP5 HMGB1 HMGB2 JDP2 KAT2B KLF9 NCOA1 NCOA3 NR0B1 PIAS1 PIAS2 PIAS3 POU2F1 POU2F2 PRKDC PRMT2 RBM23 RBM39 RELA RNF4 SMARCD1 SMARCE1 SNW1 SORBS1 SRC TAF1B TDG TRIM24 UBE3A UBR5 XRCC5 XRCC6 ZBTB17	19 interactors: CDKN2B CREBBP DIS3 DNMT3A EP300 ESR1 ESR2 GTF2I HCFC1 HK2 HK3 IRF8 ITGB5 MAX MSX2 MYC PGR TMPRSS11A TOPBP1
Entrez ID		5241	7709
HPRD ID		07077	04968
Ensembl ID		ENSG00000082175	ENSG00000116809
Uniprot IDs		P06401 Q8TDS3	Q13105
PDB IDs		1A28 1E3K 1SQN 1SR7 1ZUC 2C7A 2OVH 2OVM 2W8Y 3D90 3G8O 3HQ5 3KBA 3ZR7 3ZRA 3ZRB 4A2J 4APU	2LVR 2LVT 2LVU 2M0D 2M0E 2M0F 2Q81 3M52
Enriched GO Terms of Interacting Partners?		Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Androgen Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Hormone Chromosome Organization Regulation Of Cellular Process Chromatin Modification Cellular Response To Stimulus Response To Stimulus Chromatin Organization Cellular Response To Hormone Stimulus Regulation Of Cell Cycle Response To Steroid Hormone Organelle Organization Cellular Response To Organic Substance Intracellular Estrogen Receptor Signaling Pathway	Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Negative Regulation Of Gene Expression Gene Expression Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Response To Organic Substance Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gland Development N-terminal Peptidyl-lysine Acetylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Rhythmic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Chromatin Modification Multicellular Organismal Development Gland Morphogenesis Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Gene Expression Anatomical Structure Development Mammary Gland Development Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Chromatin Organization Cellular Response To Lipid Positive Regulation Of Cellular Biosynthetic Process Mammary Gland Duct Morphogenesis Branching Morphogenesis Of An Epithelial Tube Mammary Gland Branching Involved In Pregnancy
Tagcloud ?		antiperoxidase automatic automatically bauds computerized cutting dab get haemathoxyline immunocytochemistry immunoquantification immunoscore isc obtaining pixel plot recurrences reproducible robustness scene segmentation semilogarithmic simplicity sum summarizes telemedicine telequantification thresholds videophones	10k 1p35 1p36 aboriginal affymetrix annotated arrangements cataract descent dysmorphism encompasses epha2 ephb2 erythematous harbour lod merlin monosomy overlaps pedigree penetrant positional rash rs1441834 rs966321 ruled segregating spans volkmann
Tagcloud (Difference) ?		antiperoxidase automatic automatically bauds computerized cutting dab get haemathoxyline immunocytochemistry immunoquantification immunoscore isc obtaining pixel plot recurrences reproducible robustness scene segmentation semilogarithmic simplicity sum summarizes telemedicine telequantification thresholds videophones	10k 1p35 1p36 aboriginal affymetrix annotated arrangements cataract descent dysmorphism encompasses epha2 ephb2 erythematous harbour lod merlin monosomy overlaps pedigree penetrant positional rash rs1441834 rs966321 ruled segregating spans volkmann
Tagcloud (Intersection) ?