POU2F2 and POU2AF1

Number of citations of the paper that reports this interaction (PMID 9819426)
17

Data Source:
HPRD (in vitro, in vivo)

		POU2F2	POU2AF1
Gene Name		POU class 2 homeobox 2	POU class 2 associating factor 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Domain Specific Binding Sequence-specific DNA Binding	DNA Binding Transcription Cofactor Activity Transcription Coactivator Activity Protein Binding
	Biological Process	Mature B Cell Differentiation Immunoglobulin Secretion Involved In Immune Response Transcription From RNA Polymerase II Promoter Humoral Immune Response Positive Regulation Of Transcription, DNA-templated Cell Maturation	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Humoral Immune Response
Pathways
Drugs
Diseases
GWAS			Corneal structure ( 23291589) Primary biliary cirrhosis ( 23000144)
Protein-Protein Interactions		13 interactors: AR ESR1 GAPDH HMGA1 HMGB2 MNAT1 NR3C1 PGR POU2AF1 RXRA TBP TXNRD1 XRCC6	16 interactors: GATA2 GTF2H1 GTF2I MSX2 NAB1 PAX8 POU2F1 POU2F2 RHOXF2 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK
Entrez ID		5452	5450
HPRD ID		01251	03126
Ensembl ID		ENSG00000028277	ENSG00000110777
Uniprot IDs		B5ME60 E9PNC9 P09086	Q16633
PDB IDs		1HDP	1CQT
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Cellular Response To Steroid Hormone Stimulus RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Lipid Intracellular Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Response To Steroid Hormone Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Reproductive Process Multicellular Organismal Reproductive Process Negative Regulation Of Biosynthetic Process Response To Lipid Multicellular Organism Reproduction Response To Organic Cyclic Compound Gland Development Reproductive Structure Development Reproductive System Development Mammary Gland Duct Morphogenesis Response To Hormone Prostate Gland Development	Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Organ Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Regulation Of Metabolic Process Anatomical Structure Morphogenesis RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Cell Differentiation Ammonium Transport Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Morphogenesis Negative Regulation Of Nucleic Acid-templated Transcription Quaternary Ammonium Group Transport Negative Regulation Of RNA Biosynthetic Process System Development Cell Development Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Monoamine Transport Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Response To Stimulus Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Differentiation Transcription Initiation From RNA Polymerase II Promoter Drug Transmembrane Transport Signal Transduction Involved In Regulation Of Gene Expression Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Secretion By Cell Organ Development Positive Regulation Of BMP Signaling Pathway Anatomical Structure Development Ammonium Transmembrane Transport
Tagcloud ?		aberrations aggregate arid1a broaden carries constitutes deregulation disomy dnmt3b evolving exclusive exome fl follicular hist1h1 hodgkin implicating irf8 linker massively mutated mutually oct2 profiling recurrently stably substantially transduced uniparental
Tagcloud (Difference) ?		aberrations aggregate arid1a broaden carries constitutes deregulation disomy dnmt3b evolving exclusive exome fl follicular hist1h1 hodgkin implicating irf8 linker massively mutated mutually oct2 profiling recurrently stably substantially transduced uniparental
Tagcloud (Intersection) ?