PGR and KLF9

Number of citations of the paper that reports this interaction (PMID 12672823)
21

Data Source:
HPRD (in vivo, in vitro)

		PGR	KLF9
Gene Name		progesterone receptor	Kruppel-like factor 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrial Outer Membrane	Nucleus Nucleoplasm Cytoplasm Plasma Membrane
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Receptor Binding Steroid Binding Protein Binding Zinc Ion Binding Enzyme Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Ovulation From Ovarian Follicle Epithelial Cell Maturation Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Cell-cell Signaling Gene Expression Negative Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Epithelial Cell Proliferation Progesterone Receptor Signaling Pathway Tertiary Branching Involved In Mammary Gland Duct Morphogenesis	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Embryo Implantation Circadian Rhythm Negative Regulation Of Keratinocyte Proliferation Progesterone Receptor Signaling Pathway Cellular Response To Cortisol Stimulus Cellular Response To Thyroid Hormone Stimulus
Pathways		Nuclear signaling by ERBB4 Generic Transcription Pathway Nuclear Receptor transcription pathway Signaling by ERBB4
Drugs		Etonogestrel Desogestrel Megestrol Levonorgestrel Dydrogesterone Progesterone Fluticasone Propionate Medroxyprogesterone Norethindrone Ethynodiol Diacetate Mifepristone Norgestimate Drospirenone Danazol Allylestrenol Methyltrienolone Tanaproget Norelgestromin
Diseases
GWAS			Body mass index ( 22344221)
Protein-Protein Interactions		49 interactors: ANP32A APEX2 ARID1A BATF3 BCAS2 BRCA1 CCNA1 CCNA2 CDC25B CDK2 COPS5 CSNK2A1 CUEDC2 DAP3 DDX54 ESR1 FKBP5 HMGB1 HMGB2 JDP2 KAT2B KLF9 NCOA1 NCOA3 NR0B1 PIAS1 PIAS2 PIAS3 POU2F1 POU2F2 PRKDC PRMT2 RBM23 RBM39 RELA RNF4 SMARCD1 SMARCE1 SNW1 SORBS1 SRC TAF1B TDG TRIM24 UBE3A UBR5 XRCC5 XRCC6 ZBTB17	2 interactors: PGR SIN3A
Entrez ID		5241	687
HPRD ID		07077	04211
Ensembl ID		ENSG00000082175	ENSG00000119138
Uniprot IDs		P06401 Q8TDS3	Q13886
PDB IDs		1A28 1E3K 1SQN 1SR7 1ZUC 2C7A 2OVH 2OVM 2W8Y 3D90 3G8O 3HQ5 3KBA 3ZR7 3ZRA 3ZRB 4A2J 4APU
Enriched GO Terms of Interacting Partners?		Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Androgen Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Hormone Chromosome Organization Regulation Of Cellular Process Chromatin Modification Cellular Response To Stimulus Response To Stimulus Chromatin Organization Cellular Response To Hormone Stimulus Regulation Of Cell Cycle Response To Steroid Hormone Organelle Organization Cellular Response To Organic Substance Intracellular Estrogen Receptor Signaling Pathway	Response To Methylglyoxal Negative Regulation Of Histone H3-K27 Acetylation Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Rhythmic Process Positive Regulation Of Chromatin Silencing Progesterone Receptor Signaling Pathway Mammary Gland Branching Involved In Pregnancy Ovulation From Ovarian Follicle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Defense Response To Virus By Host Transcription From RNA Polymerase II Promoter Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Histone Acetylation Epithelial Cell Maturation Ovulation Regulation Of Gene Silencing Negative Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Acetylation Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Defense Response To Virus By Host Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of DNA Binding Regulation Of Histone Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Glucose Stimulus Mammary Gland Duct Morphogenesis Histone Deacetylation Protein Deacetylation Cellular Glucose Homeostasis Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Carbohydrate Stimulus Negative Regulation Of Gene Expression, Epigenetic Cellular Response To Organic Substance Maternal Process Involved In Female Pregnancy Regulation Of Defense Response To Virus Negative Regulation Of Protein Localization To Nucleus
Tagcloud ?		antiperoxidase automatic automatically bauds computerized cutting dab get haemathoxyline immunocytochemistry immunoquantification immunoscore isc obtaining pixel plot recurrences reproducible robustness scene segmentation semilogarithmic simplicity sum summarizes telemedicine telequantification thresholds videophones	boxes colorectal cycloheximide delay directly downregulated ectopic gc glioblastoma hcc hep1 hepatocellular hepg2 kruppel onset pharmacological plays positively promote proximal remarkably restoration significance sk stability sufficient suppressor tumors unclear
Tagcloud (Difference) ?		antiperoxidase automatic automatically bauds computerized cutting dab get haemathoxyline immunocytochemistry immunoquantification immunoscore isc obtaining pixel plot recurrences reproducible robustness scene segmentation semilogarithmic simplicity sum summarizes telemedicine telequantification thresholds videophones	boxes colorectal cycloheximide delay directly downregulated ectopic gc glioblastoma hcc hep1 hepatocellular hepg2 kruppel onset pharmacological plays positively promote proximal remarkably restoration significance sk stability sufficient suppressor tumors unclear
Tagcloud (Intersection) ?