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PGR and BATF3
Number of citations of the paper that reports this interaction (PubMedID
12101239
)
66
Data Source:
BioGRID
(two hybrid, pull down)
HPRD
(two hybrid, in vitro)
PGR
BATF3
Description
progesterone receptor
basic leucine zipper ATF-like transcription factor 3
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Plasma Membrane
Membrane
Chromatin
Nucleus
Nucleoplasm
Nucleolus
Cytosol
RNA Polymerase II Transcription Regulator Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Coactivator Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Nuclear Steroid Receptor Activity
Nuclear Receptor Activity
Signaling Receptor Binding
Steroid Binding
Protein Binding
Zinc Ion Binding
Lipid Binding
Enzyme Binding
Estrogen Response Element Binding
Identical Protein Binding
Sequence-specific DNA Binding
Metal Ion Binding
ATPase Binding
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Ovulation From Ovarian Follicle
Epithelial Cell Maturation
Glandular Epithelial Cell Maturation
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Signal Transduction
Cell-cell Signaling
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Mammary Gland Development
Paracrine Signaling
Steroid Hormone Receptor Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Lung Alveolus Development
Regulation Of Epithelial Cell Proliferation
Progesterone Receptor Signaling Pathway
Maintenance Of Protein Location In Nucleus
Tertiary Branching Involved In Mammary Gland Duct Morphogenesis
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Response To Virus
Myeloid Dendritic Cell Differentiation
Dendritic Cell Differentiation
Integrated Stress Response Signaling
Pathways
Nuclear signaling by ERBB4
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors
Estrogen-dependent gene expression
Developmental Lineage of Mammary Gland Luminal Epithelial Cells
Developmental Lineage of Mammary Gland Alveolar Cells
Drugs
Etonogestrel
Desogestrel
Megestrol acetate
Levonorgestrel
Dydrogesterone
Progesterone
Spironolactone
Lindane
Fluticasone propionate
Medroxyprogesterone acetate
Mitotane
Norethisterone
Mometasone
Ethynodiol diacetate
Mifepristone
Norgestimate
Drospirenone
Danazol
Oxybenzone
Allylestrenol
Phthalic Acid
Metribolone
Tanaproget
Telapristone acetate
Asoprisnil
Norelgestromin
Gestodene
Hydroxyprogesterone caproate
Ulipristal
Fluticasone furoate
Dienogest
Medrogestone
Norgestrel
Homosalate
Enzacamene
Gestrinone
Darolutamide
Demegestone
Fluticasone
Mometasone furoate
Segesterone acetate
Diseases
GWAS
Diastolic blood pressure (
30224653
)
Length of menstrual cycle (
30202859
)
Menarche (age at onset) (
25231870
)
Severity of nausea and vomiting of pregnancy (
29563502
)
Asthma (
32296059
)
Leprosy (
25642632
)
Multiple sclerosis (
31604244
)
Thiopurine-induced leukopenia in inflammatory bowel disease (conditioned on rs116855232) (
29923122
)
Type 1 diabetes (
34012112
)
Interacting Genes
55 interacting genes:
ANP32A
APEX2
ARID1A
BATF3
BCAS2
BMI1
BRCA1
CCNA1
CCNA2
CDC25B
CDK2
COPS5
CSNK2A1
CUEDC2
DAP3
DDX54
DNAJA1
DNAJC7
ESR1
FKBP5
HMGB1
HMGB2
HSP90AB1
HSPA1A
JDP2
KAT2B
KLF9
NCOA1
NCOA3
NR0B1
PIAS1
PIAS2
PIAS3
POU2F1
POU2F2
PRKDC
PRMT2
RBM23
RBM39
RELA
RNF4
SGTA
SMARCD1
SMARCE1
SNW1
SORBS1
SRC
TAF1B
TDG
TRIM24
UBE3A
UBR5
XRCC5
XRCC6
ZBTB17
21 interacting genes:
AGXT
APPL1
ATF3
ATF4
BACH2
BATF
CEBPA
CEBPE
CEBPG
CRK
DBP
DDIT3
EPAS1
FOSL1
GPATCH2L
MAFF
MAFG
NFATC2IP
PGR
RHOXF2
STAT3
Entrez ID
5241
55509
HPRD ID
07077
18081
Ensembl ID
ENSG00000082175
ENSG00000123685
Uniprot IDs
P06401
Q9NR55
PDB IDs
1A28
1E3K
1SQN
1SR7
1ZUC
2C7A
2OVH
2OVM
2W8Y
3D90
3G8O
3HQ5
3KBA
3ZR7
3ZRA
3ZRB
4A2J
4APU
4OAR
5CC0
Enriched GO Terms of Interacting Partners
?
Nucleoplasm
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Transcription Coactivator Activity
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Metabolic Process
Chromatin Organization
Chromatin
Chromatin Remodeling
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleic Acid Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Cellular Response To Stress
Cellular Response To Hormone Stimulus
Response To Hormone
Nuclear Receptor Binding
Macromolecule Metabolic Process
Double-strand Break Repair Via Nonhomologous End Joining
Nucleobase-containing Compound Metabolic Process
Hormone-mediated Signaling Pathway
Regulation Of Cellular Response To Stress
Nuclear Receptor-mediated Signaling Pathway
Cellular Response To Oxygen-containing Compound
Protein-containing Complex
DNA Binding
Cellular Response To Lipid
Intracellular Receptor Signaling Pathway
DNA Recombination
Regulation Of DNA Metabolic Process
RNA Polymerase II Transcription Regulator Complex
DNA-binding Transcription Factor Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Integrated Stress Response Signaling
Chromatin
Sequence-specific Double-stranded DNA Binding
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
DNA Binding
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Metabolic Process
Nucleus
Regulation Of Macromolecule Metabolic Process
Sequence-specific DNA Binding
Regulation Of Primary Metabolic Process
Identical Protein Binding
Regulation Of Metabolic Process
CHOP-ATF3 Complex
CHOP-ATF4 Complex
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Epithelial Cell Maturation
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Intracellular Signaling Cassette
CHOP-C/EBP Complex
Transcription Regulator Complex
DNA-templated Transcription
Negative Regulation Of Transcription By RNA Polymerase II
Myeloid Cell Differentiation
Transcription Cis-regulatory Region Binding
Developmental Process
GDF15-GFRAL Signaling Pathway
Intracellular Signal Transduction
Positive Regulation Of Cytokine Production
MRNA Transcription By RNA Polymerase II
Cellular Developmental Process
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Tagcloud (Intersection)
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